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Scientific data management is at a critical juncture, driven by exponential data growth, increasing cross-domain dependencies, and a severe reproducibility crisis in modern research. Traditional centralized data management approaches are…

Databases · Computer Science 2025-04-30 Sebastian Beyvers , Jannis Hochmuth , Lukas Brehm , Maria Hansen , Alexander Goesmann , Frank Förster

Infrastructure shapes societies and scientific discovery. Traditional scientific infrastructure, often static and fragmented, leads to issues like data silos, lack of interoperability and reproducibility, and unsustainable short-lived…

Neurons and Cognition · Quantitative Biology 2025-08-15 Satrajit S. Ghosh

Modern tools for biological research, especially microscopy, have rapidly advanced in recent years, which has led to the generation of increasingly large amounts of data on a regular basis. The result is that scientists desperately need…

Other Quantitative Biology · Quantitative Biology 2021-08-18 Andrey Andreev , Tom Morrell , Kristin Briney , Sandra Gesing , Uri Manor

The most pressing problems in science are neither empirical nor theoretical, but infrastructural. Scientific practice is defined by coproductive, mutually reinforcing infrastructural deficits and incentive systems that everywhere constrain…

General Literature · Computer Science 2022-09-16 Jonny L. Saunders

Data is the most powerful decision-making tool at our disposal. However, despite the exponentially growing volumes of data generated in the world, putting it to effective use still presents many challenges. Relevant data seems to be never…

Databases · Computer Science 2021-11-12 Sergii Mikhtoniuk , Ozge Nilay Yalcin

For AI technology to fulfill its full promises, we must have effective means to ensure Responsible AI behavior and curtail potential irresponsible use, e.g., in areas of privacy protection, human autonomy, robustness, and prevention of…

Computers and Society · Computer Science 2022-05-13 Wenjing Chu

Scientific communities naturally tend to organize around data ecosystems created by the combination of their observational devices, their data repositories, and the workflows essential to carry their research from observation to discovery.…

Networking and Internet Architecture · Computer Science 2021-06-30 Mark Asch , François Bodin , Micah Beck , Terry Moore , Michela Taufer , Martin Swany , Jean-Pierre Vilotte

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

In the current paradigm of digital personalized services, the centralized management of personal data raises significant privacy concerns, security vulnerabilities, and diminished individual autonomy over sensitive information. Despite…

Cryptography and Security · Computer Science 2025-09-12 Osama Zafar , Mina Namazi , Yuqiao Xu , Youngjin Yoo , Erman Ayday

This is a thought piece on data-intensive science requirements for databases and science centers. It argues that peta-scale datasets will be housed by science centers that provide substantial storage and processing for scientists who access…

Databases · Computer Science 2007-05-23 Jim Gray , David T. Liu , Maria Nieto-Santisteban , Alexander S. Szalay , David DeWitt , Gerd Heber

The Hybrid Technology Hub and many other research centers work in cross-functional teams whose workflow is not necessarily linear and where in many cases technology advances are done through parallel work. The lack of proper tools and…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-18 Pavel Vazquez , Kayoko Shoji , Steffen Novik , Stefan Krauss , Simon Rayner

The Web is a ubiquitous economic, educational, and collaborative space. However, it also serves as a haven for personal information harvesting. Existing decentralised Web-based ecosystems, such as Solid, aim to combat personal data…

Databases · Computer Science 2020-08-17 Ruben Taelman , Simon Steyskal , Sabrina Kirrane

The rapid advancement of ML models in critical sectors such as healthcare, finance, and security has intensified the need for robust data security, model integrity, and reliable outputs. Large multimodal foundational models, while crucial…

Cryptography and Security · Computer Science 2024-12-13 Hongyang Zhang , Yue Zhao , Claudio Angione , Harry Yang , James Buban , Ahmad Farhan , Fielding Johnston , Patrick Colangelo

The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

With the shifting focus of organizations and governments towards digitization of academic and technical documents, there has been an increasing need to use this reserve of scholarly documents for developing applications that can facilitate…

Digital Libraries · Computer Science 2016-06-07 Samiya Khan , Kashish A. Shakil , Mansaf Alam

Scientific research increasingly depends on robust and scalable IT infrastructures to support complex computational workflows. With the proliferation of services provided by research infrastructures, NRENs, and commercial cloud providers,…

The increasingly collaborative, globalized nature of scientific research combined with the need to share data and the explosion in data volumes present an urgent need for a scientific data management system (SDMS). An SDMS presents a…

Databases · Computer Science 2020-04-09 Dale Stansberry , Suhas Somnath , Jessica Breet , Gregory Shutt , Mallikarjun Shankar

Storing data is easy, but finding and using data is not. It is desirable that the data is stored in a structured format, which can be preserved and retrieved in future. Creating Metadata for the data is one way of creating structured data…

Information Theory · Computer Science 2011-01-04 Ranjeet Devarakonda , Giri Palanisamy , Jim Green

Making available and archiving scientific results is for the most part still considered the task of classical publishing companies, despite the fact that classical forms of publishing centered around printed narrative articles no longer…

Digital Libraries · Computer Science 2015-07-23 Tobias Kuhn , Christine Chichester , Michael Krauthammer , Michel Dumontier
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