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Constrained combinatorial optimization problems, which are ubiquitous in industry, can be solved by quantum algorithms such as quantum annealing (QA) and the quantum approximate optimization algorithm (QAOA). In these quantum algorithms,…

Quantum Physics · Physics 2024-12-17 Puya Mirkarimi , Ishaan Shukla , David C. Hoyle , Ross Williams , Nicholas Chancellor

Quantum annealing is a generic algorithm using quantum-mechanical fluctuations to search for the solution of an optimization problem. The present paper first reviews the fundamentals of quantum annealing and then reports on preliminary…

Disordered Systems and Neural Networks · Physics 2010-06-10 Masayuki Ohzeki , Hidetoshi Nishimori

In the quantum optimization paradigm, variational quantum algorithms face challenges with hardware-specific and instance-dependent parameter tuning, which can lead to computational inefficiencies. The promising potential of parameter…

Binary optimisation tasks are ubiquitous in areas ranging from logistics to cryptography. The exponential complexity of such problems means that the performance of traditional computational methods decreases rapidly with increasing problem…

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

We present the mapping of a class of simplified air traffic management (ATM) problems (strategic conflict resolution) to quadratic unconstrained boolean optimization (QUBO) problems. The mapping is performed through an original…

Ising computing provides a new computing paradigm for many hard combinatorial optimization problems. Ising computing essentially tries to solve the quadratic unconstrained binary optimization problem, which is also described by the Ising…

Emerging Technologies · Computer Science 2019-08-02 Chase Cook , Wentian Jin , Sheldon X. -D. Tan

Current quantum annealing (QA) hardware suffers from practical limitations such as finite temperature, sparse connectivity, small qubit numbers, and control error. We propose new algorithms for mapping boolean constraint satisfaction…

Quantum Physics · Physics 2016-03-11 Zhengbing Bian , Fabian Chudak , Robert Israel , Brad Lackey , William G. Macready , Aidan Roy

Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice…

Quantum Physics · Physics 2024-02-15 Anders Irbäck , Lucas Knuthson , Sandipan Mohanty , Carsten Peterson

Transcription factors regulate gene expression, but how these proteins recognize and specifically bind to their DNA targets is still debated. Machine learning models are effective means to reveal interaction mechanisms. Here we studied the…

Quantum Physics · Physics 2018-03-02 Richard Y. Li , Rosa Di Felice , Remo Rohs , Daniel A. Lidar

Optimization or sampling of arbitrary pairwise Ising models, in a quantum annealing protocol of constrained interaction topology, can be enabled by a minor-embedding procedure. The logical problem of interest is transformed to a physical…

Quantum Physics · Physics 2021-05-20 Jack Raymond , Ndiamé Ndiaye , Gautam Rayaprolu , Andrew King

Binary optimization is a central problem in mathematical optimization and its applications are abundant. To solve this problem, we propose a new class of continuous optimization techniques which is based on Mathematical Programming with…

Optimization and Control · Mathematics 2017-12-07 Ganzhao Yuan , Bernard Ghanem

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

Noisy intermediate-scale quantum (NISQ) devices are spearheading the second quantum revolution. Of these, quantum annealers are the only ones currently offering real world, commercial applications on as many as 5000 qubits. The size of…

We develop a heuristic graph coloring approximation algorithm that uses the D-Wave 2X as an independent set sampler and evaluate its performance against a fully classical implementation. A randomly generated set of small but hard graph…

Quantum Physics · Physics 2020-12-09 Julia Kwok , Kristen Pudenz

In this article, we show how to map a sampling of the hardest artificial intelligence problems in space exploration onto equivalent Ising models that then can be attacked using quantum annealing implemented in D-Wave machine. We overview…

We propose a new method for solving binary optimization problems under inequality constraints using a quantum annealer. To deal with inequality constraints, we often use slack variables, as in previous approaches. When we use slack…

Quantum Physics · Physics 2020-12-14 Kouki Yonaga , Masamichi J. Miyama , Masayuki Ohzeki

We introduce two quantum algorithms for solving structured prediction problems. We first show that a stochastic gradient descent that uses the quantum minimum finding algorithm and takes its probabilistic failure into account solves the…

Machine Learning · Computer Science 2021-07-05 Behrooz Sepehry , Ehsan Iranmanesh , Michael P. Friedlander , Pooya Ronagh

Current quantum computing devices have different strengths and weaknesses depending on their architectures. This means that flexible approaches to circuit design are necessary. We address this task by introducing a novel space-efficient…

In this paper, we initiate the study of quantum algorithms in the Graph Drawing research area. We focus on two foundational drawing standards: 2-level drawings and book layouts. Concerning $2$-level drawings, we consider the problems of…

Data Structures and Algorithms · Computer Science 2023-07-18 Susanna Caroppo , Giordano Da Lozzo , Giuseppe Di Battista
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