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In scanning microscopy based imaging techniques, there is a need to develop novel data acquisition schemes that can reduce the time for data acquisition and minimize sample exposure to the probing radiation. Sparse sampling schemes are…

Signal Processing · Electrical Eng. & Systems 2018-03-09 Yan Zhang , G. M. Dilshan Godaliyadda , Nicola Ferrier , Emine B. Gulsoy , Charles A. Bouman , Charudatta Phatak

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Low dose CT is of great interest in these days. Dose reduction raises noise level in projections and decrease image quality in reconstructions. Model based image reconstruction can combine statistical noise model together with prior…

Medical Physics · Physics 2019-10-16 Kaichao Liang , Li Zhang , Yirong Yang , HongKai Yang , Yuxiang Xing

Computed tomography (CT) has played a vital role in medical diagnosis, assessment, and therapy planning, etc. In clinical practice, concerns about the increase of X-ray radiation exposure attract more and more attention. To lower the X-ray…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhicheng Zhang , Xiaokun Liang , Wei Zhao , Lei Xing

Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired…

Parametric imaging of nuclear medicine data exploits dynamic functional images in order to reconstruct maps of kinetic parameters related to the metabolism of a specific tracer injected in the biological tissue. From a computational…

Numerical Analysis · Mathematics 2019-08-30 Serena Crisci , Michele Piana , Valeria Ruggiero , Mara Scussolini

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Radiation exposure in positron emission tomography (PET) imaging limits its usage in the studies of radiation-sensitive populations, e.g., pregnant women, children, and adults that require longitudinal imaging. Reducing the PET radiotracer…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Viswanath P. Sudarshan , Uddeshya Upadhyay , Gary F. Egan , Zhaolin Chen , Suyash P. Awate

Deep neural networks (DNNs) have shown to provide superb performance in many real life applications, but their large computation cost and storage requirement have prevented them from being deployed to many edge and internet-of-things (IoT)…

Neural and Evolutionary Computing · Computer Science 2021-12-22 Minghai Qin , Tianyun Zhang , Fei Sun , Yen-Kuang Chen , Makan Fardad , Yanzhi Wang , Yuan Xie

K-SVD algorithm has been successfully applied to image denoising tasks dozens of years but the big bottleneck in speed and accuracy still needs attention to break. For the sparse coding stage in K-SVD, which involves $\ell_{0}$ constraint,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Quan Xiao , Canhong Wen , Zirui Yan

Deep neural networks have been proved efficient for medical image denoising. Current training methods require both noisy and clean images. However, clean images cannot be acquired for many practical medical applications due to naturally…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Dufan Wu , Kuang Gong , Kyungsang Kim , Quanzheng Li

In image denoising networks, feature scaling is widely used to enlarge the receptive field size and reduce computational costs. This practice, however, also leads to the loss of high-frequency information and fails to consider within-scale…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Hao Shen , Zhong-Qiu Zhao , Wandi Zhang

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Autonomous systems need to process large-scale, sparse, and irregular point clouds with limited compute resources. Consequently, it is essential to develop LiDAR perception methods that are both efficient and effective. Although naively…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Tuo Feng , Wenguan Wang , Fan Ma , Yi Yang

Deep learning based solutions are being succesfully implemented for a wide variety of applications. Most notably, clinical use-cases have gained an increased interest and have been the main driver behind some of the cutting-edge data-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Theodor Cheslerean-Boghiu , Felix C. Hofmann , Manuel Schultheiß , Franz Pfeiffer , Daniela Pfeiffer , Tobias Lasser

A major challenge in computed tomography (CT) is how to minimize patient radiation exposure without compromising image quality and diagnostic performance. The use of deep convolutional (Conv) neural networks for noise reduction in Low-Dose…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Chenyu You , Linfeng Yang , Yi Zhang , Ge Wang

We present a technique for jointly denoising bursts of images taken from a handheld camera. In particular, we propose a convolutional neural network architecture for predicting spatially varying kernels that can both align and denoise…

Computer Vision and Pattern Recognition · Computer Science 2018-03-30 Ben Mildenhall , Jonathan T. Barron , Jiawen Chen , Dillon Sharlet , Ren Ng , Robert Carroll

We present a novel kernel-based machine learning algorithm for identifying the low-dimensional geometry of the effective dynamics of high-dimensional multiscale stochastic systems. Recently, the authors developed a mathematical framework…

Dynamical Systems · Mathematics 2020-02-04 Andreas Bittracher , Stefan Klus , Boumediene Hamzi , Péter Koltai , Christof Schütte
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