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Robust perception and reasoning require consistency across sensory modalities. Yet current multimodal models often violate this principle, yielding contradictory predictions for visual and textual representations of the same concept. Rather…

Artificial Intelligence · Computer Science 2026-03-27 Zirui Zhang , Haoyu Dong , Kexin Pei , Chengzhi Mao

DNA Language Models, such as GROVER, DNABERT2 and the Nucleotide Transformer, operate on DNA sequences that inherently contain sequencing errors, mutations, and laboratory-induced noise, which may significantly impact model performance.…

Computation and Language · Computer Science 2025-03-04 Hyunwoo Yoo , Haebin Shin , Kaidi Xu , Gail Rosen

In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the…

Information Theory · Computer Science 2023-11-17 Huawei Wu

This paper introduces a new solution to DNA storage that integrates all three steps of retrieval, namely clustering, reconstruction, and error correction. DNA-correcting codes are presented as a unique solution to the problem of ensuring…

Information Theory · Computer Science 2024-07-02 Avital Boruchovsky , Daniella Bar-Lev , Eitan Yaakobi

This paper presents a novel approach to advancing artificial intelligence (AI) through the development of the Complex Recurrent Spectral Network ($\mathbb{C}$-RSN), an innovative variant of the Recurrent Spectral Network (RSN) model. The…

Machine Learning · Computer Science 2023-12-13 Lorenzo Chicchi , Lorenzo Giambagli , Lorenzo Buffoni , Raffaele Marino , Duccio Fanelli

Lifelong person re-identification (LReID) exhibits a contradictory relationship between intra-domain discrimination and inter-domain gaps when learning from continuous data. Intra-domain discrimination focuses on individual nuances (i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Shiben Liu , Huijie Fan , Qiang Wang , Weihong Ren , Yandong Tang , Yang Cong

DNA sequence encoding is fundamental to gene function prediction, protein synthesis, and diverse downstream biological tasks. Despite the substantial progress achieved by large-scale DNA sequence pretraining, existing studies have…

Machine Learning · Computer Science 2026-04-21 Zhijiang Tang , Jiaxin Qi , Yan Cui , Jinli Ou , Yuhua Zheng , Jianqiang Huang

Recurrent convolution (RC) shares the same convolutional kernels and unrolls them multiple steps, which is originally proposed to model time-space signals. We argue that RC can be viewed as a model compression strategy for deep…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Zhendong Zhang , Cheolkon Jung

We propose rectified factor networks (RFNs) to efficiently construct very sparse, non-linear, high-dimensional representations of the input. RFN models identify rare and small events in the input, have a low interference between code units,…

Machine Learning · Computer Science 2018-01-31 Djork-Arné Clevert , Andreas Mayr , Thomas Unterthiner , Sepp Hochreiter

Existing facial image super-resolution (SR) methods focus mostly on improving artificially down-sampled low-resolution (LR) imagery. Such SR models, although strong at handling artificial LR images, often suffer from significant performance…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Zhiyi Cheng , Xiatian Zhu , Shaogang Gong

Contrastive Learning (CL) enhances the training of sequential recommendation (SR) models through informative self-supervision signals. Existing methods often rely on data augmentation strategies to create positive samples and promote…

Information Retrieval · Computer Science 2026-04-06 Zhikai Wang , Yanyan Shen , Zexi Zhang , Li He , Yichun Li , Hao Gu , Yinghua Zhang

The inverse design of RNA three-dimensional (3D) structures is crucial for engineering functional RNAs in synthetic biology and therapeutics. While recent deep learning approaches have advanced this field, they are typically optimized and…

Machine Learning · Computer Science 2026-05-11 Tianmeng Hu , Yongzheng Cui , Biao Luo , Ke Li

Motivation: Next generation methods of DNA sequencing produce relatively high rate of reading errors, which interfere with de novo genome assembly of newly sequenced organisms and particularly affect the quality of SNP detection important…

Genomics · Quantitative Biology 2019-07-31 Oleg Fokin , Anastasia Bakulina , Igor Seledtsov , Victor Solovyev

Contrastive representation learning seeks to acquire useful representations by estimating the shared information between multiple views of data. Here, the choice of data augmentation is sensitive to the quality of learned representations:…

Machine Learning · Statistics 2023-01-18 Kyungmin Lee , Jinwoo Shin

Multi-objective preference alignment in language models often encounters a challenging trade-off: optimizing for one human preference (e.g., helpfulness) frequently compromises others (e.g., harmlessness) due to the inherent conflicts…

Computation and Language · Computer Science 2025-04-16 Zhihao Xu , Yongqi Tong , Xin Zhang , Jun Zhou , Xiting Wang

We introduce a novel neural network module that adeptly handles recursive data flow in neural network architectures. At its core, this module employs a self-consistent approach where a set of recursive equations is solved iteratively,…

Computation and Language · Computer Science 2024-10-07 Konstantin Kolokolov , Pavel Pekichev , Karthik Raghunathan

Pre-trained large language models demonstrate potential in extracting information from DNA sequences, yet adapting to a variety of tasks and data modalities remains a challenge. To address this, we propose DNAGPT, a generalized DNA…

Genomics · Quantitative Biology 2023-09-01 Daoan Zhang , Weitong Zhang , Yu Zhao , Jianguo Zhang , Bing He , Chenchen Qin , Jianhua Yao

Pretrained language models such as BERT, GPT have shown great effectiveness in language understanding. The auxiliary predictive tasks in existing pretraining approaches are mostly defined on tokens, thus may not be able to capture…

Computation and Language · Computer Science 2020-06-19 Hongchao Fang , Sicheng Wang , Meng Zhou , Jiayuan Ding , Pengtao Xie

RNA inverse sequence design has broad biological and engineering applications, but computational methods for practical design queries remain limited. Such queries may impose several constraints at once, including target folds or motifs,…

Quantitative Methods · Quantitative Biology 2026-05-11 Michael Lindsey

Language models contain ranking-based knowledge and are powerful solvers of in-context ranking tasks. For instance, they may have parametric knowledge about the ordering of countries by size or may be able to rank product reviews by…

Machine Learning · Computer Science 2024-02-06 Niklas Stoehr , Pengxiang Cheng , Jing Wang , Daniel Preotiuc-Pietro , Rajarshi Bhowmik
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