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Purpose: We aim to develop a robust 4D MRI method for large FOVs enabling the extraction of irregular respiratory motion that is readily usable with all MRI machines and thus applicable to support a wide range of interventional settings.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Gino Gulamhussene , Fabian Joeres , Marko Rak , Maciej Pech , Christian Hansen

Background: Respiratory-resolved four-dimensional magnetic resonance imaging (4D-MRI) provides essential motion information for accurate radiation treatments of mobile tumors. However, obtaining high-quality 4D-MRI suffers from long…

Medical Physics · Physics 2023-08-04 Maarten Terpstra , Matteo Maspero , Joost Verhoeff , Cornelis van den Berg

Accurately estimating and correcting the motion artifacts are crucial for 3D image reconstruction of the abdominal and in-utero magnetic resonance imaging (MRI). The state-of-art methods are based on slice-to-volume registration (SVR) where…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Tong Zhang , Laurence H. Jackson , Alena Uus , James R. Clough , Lisa Story , Mary A. Rutherford , Joseph V. Hajnal , Maria Deprez

Reconstructing dynamic, time-varying scenes with computed tomography (4D-CT) is a challenging and ill-posed problem common to industrial and medical settings. Existing 4D-CT reconstructions are designed for sparse sampling schemes that…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Albert W. Reed , Hyojin Kim , Rushil Anirudh , K. Aditya Mohan , Kyle Champley , Jingu Kang , Suren Jayasuriya

Motion information from 4D medical imaging offers critical insights into dynamic changes in patient anatomy for clinical assessments and radiotherapy planning and, thereby, enhances the capabilities of 3D image analysis. However, inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xia Li , Runzhao Yang , Xiangtai Li , Antony Lomax , Ye Zhang , Joachim Buhmann

Intra-frame motion blurring, as a major challenge in free-breathing dynamic MRI, can be reduced if high temporal resolution can be achieved. To address this challenge, this work proposes a highly-accelerated 4D (3D+time) real-time MRI…

Medical Physics · Physics 2022-08-12 Li Feng

This study presents an unsupervised, motion-resolved reconstruction framework for high-resolution, free-breathing pulmonary magnetic resonance imaging (MRI), utilizing a three-dimensional Gaussian representation (3DGS). The proposed method…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Tengya Peng , Ruyi Zha , Qing Zou

Organ motion poses an unresolved challenge in image-guided interventions. In the pursuit of solving this problem, the research field of time-resolved volumetric magnetic resonance imaging (4D MRI) has evolved. However, current techniques…

Image and Video Processing · Electrical Eng. & Systems 2023-01-20 Gino Gulamhussene , Anneke Meyer , Marko Rak , Oleksii Bashkanov , Jazan Omari , Maciej Pech , Christian Hansen

4D Computed Tomography (4DCT) is widely used for many clinical applications such as radiotherapy treatment planning, PET and ventilation imaging. However, common 4DCT methods reconstruct multiple breath cycles into a single, arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Yuliang Huang , Bjoern Eiben , Kris Thielemans , Jamie R. McClelland

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

Medical Physics · Physics 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke

Resting-state functional Magnetic Resonance Imaging (fMRI) is a powerful imaging technique for studying functional development of the brain in utero. However, unpredictable and excessive movement of fetuses have limited its clinical…

Radiation therapy presents a need for dynamic tracking of a target tumor volume. Fiducial markers such as implanted gold seeds have been used to gate radiation delivery but the markers are invasive and gating significantly increases…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Markus D. Foote , Blake E. Zimmerman , Amit Sawant , Sarang Joshi

4D time-space reconstruction of dynamic events or deforming objects using X-ray computed tomography (CT) is an important inverse problem in non-destructive evaluation. Conventional back-projection based reconstruction methods assume that…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 K. Aditya Mohan , Massimiliano Ferrucci , Chuck Divin , Garrett A. Stevenson , Hyojin Kim

We propose an unsupervised deep learning algorithm for the motion-compensated reconstruction of 5D cardiac MRI data from 3D radial acquisitions. Ungated free-breathing 5D MRI simplifies the scan planning, improves patient comfort, and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Joseph Kettelkamp , Ludovica Romanin , Davide Piccini , Sarv Priya , Mathews Jacob

Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis

Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Simone Garzia , Patryk Rygiel , Sven Dummer , Filippo Cademartiri , Simona Celi , Jelmer M. Wolterink

Intrafraction motion can play a pivotal role in the success of abdominal and thoracic radiation therapy. Hybrid magnetic resonance-guided radiotherapy systems have the potential to control for intrafraction motion. Recently, we introduced…

The reconstruction of 3D cine-MRI is challenged by highly undersampled k-space data in each cine frame, due to the slow speed of MR signal acquisition. We proposed a machine learning-based framework, spatial and temporal implicit neural…

Medical Physics · Physics 2023-08-22 Hua-Chieh Shao , Tielige Mengke , Jie Deng , You Zhang

This paper introduces a deep neural network based method, i.e., DeepOrganNet, to generate and visualize high-fidelity 3D / 4D organ geometric models from single-view medical image in real time. Traditional 3D / 4D medical image…

Graphics · Computer Science 2019-07-23 Yifan Wang , Zichun Zhong , Jing Hua
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