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Hero-class HPC simulations rely on Adaptive Mesh Refinement (AMR) to reduce compute and memory demands while maintaining accuracy. This work analyzes the performance of Parthenon, a block-structured AMR benchmark, on CPU-GPU systems. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-25 Akash Poptani , Alireza Khadem , Scott Mahlke , Jonah Miller , Joshua Dolence , Reetuparna Das

In this paper we present a Bayesian reinforcement learning framework that allows robotic manipulators to adaptively recover from random mechanical failures autonomously, hence being survivable. To this end, we formulate the framework of…

Robotics · Computer Science 2020-10-21 Sayyed Jaffar Ali Raza , Apan Dastider , Mingjie Lin

Following a recent surge in using history-based methods for resolving perceptual aliasing in reinforcement learning, we introduce an algorithm based on the feature reinforcement learning framework called PhiMDP. To create a practical…

Artificial Intelligence · Computer Science 2011-08-19 Phuong Nguyen , Peter Sunehag , Marcus Hutter

We developed an adaptive structure learning method of Restricted Boltzmann Machine (RBM) which can generate/annihilate neurons by self-organizing learning method according to input patterns. Moreover, the adaptive Deep Belief Network (DBN)…

Neural and Evolutionary Computing · Computer Science 2018-07-12 Shin Kamada , Takumi Ichimura

Large language models (LLMs) are vulnerable to adversarial attacks that can elicit harmful responses. Defending against such attacks remains challenging due to the opacity of jailbreaking mechanisms and the high computational cost of…

Machine Learning · Computer Science 2025-03-21 Lei Yu , Virginie Do , Karen Hambardzumyan , Nicola Cancedda

Large Language Models (LLMs) are increasingly embedded in autonomous systems and public-facing environments, yet they remain susceptible to jailbreak vulnerabilities that may undermine their security and trustworthiness. Adversarial…

Machine Learning · Computer Science 2025-05-15 David Khachaturov , Robert Mullins

We propose new methodologies for both unlearning random set of samples and class unlearning and show that they outperform existing methods. The main driver of our unlearning methods is the similarity of predictions to a retrained model on…

Machine Learning · Computer Science 2025-12-09 Ali Ebrahimpour-Boroojeny

The escalating threat of adversarial attacks on deep learning models, particularly in security-critical fields, has underscored the need for robust deep learning systems. Conventional robustness evaluations have relied on adversarial…

Cryptography and Security · Computer Science 2024-11-19 Ping Guo , Cheng Gong , Xi Lin , Zhiyuan Yang , Qingfu Zhang

Deep learning has emerged as a leading approach for Automatic Modulation Classification (AMC), demonstrating superior performance over traditional methods. However, vulnerability to adversarial attacks and susceptibility to data…

Machine Learning · Computer Science 2025-11-04 Ali Owfi , Amirmohammad Bamdad , Tolunay Seyfi , Fatemeh Afghah

Experience replay is an essential component in deep reinforcement learning (DRL), which stores the experiences and generates experiences for the agent to learn in real time. Recently, prioritized experience replay (PER) has been proven to…

Hardware Architecture · Computer Science 2024-03-06 Mengyuan Li , Arman Kazemi , Ann Franchesca Laguna , X. Sharon Hu

Finite element discretizations of problems in computational physics often rely on adaptive mesh refinement (AMR) to preferentially resolve regions containing important features during simulation. However, these spatial refinement strategies…

Computational Engineering, Finance, and Science · Computer Science 2022-09-27 Corbin Foucart , Aaron Charous , Pierre F. J. Lermusiaux

Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…

Quantitative Methods · Quantitative Biology 2022-10-25 Shengjia Chen , Nikunj Gupta , Woodward B. Galbraith , Valay Shah , Jacopo Cirrone

Machine learning and deep learning have gained popularity and achieved immense success in Drug discovery in recent decades. Historically, machine learning and deep learning models were trained on either structural data or chemical…

Machine Learning · Statistics 2019-09-18 Huy Ngoc Pham , Trung Hoang Le

AI-based in silico methods have improved protein structure prediction but often struggle with large protein complexes (PCs) involving multiple interacting proteins due to missing 3D spatial cues. Experimental techniques like Cryo-EM are…

Model-based reinforcement learning has attracted much attention due to its high sample efficiency and is expected to be applied to real-world robotic applications. In the real world, as unobservable disturbances can lead to unexpected…

Robotics · Computer Science 2025-05-26 Taisuke Kobayashi

RL-based medical questionnaire systems have shown great potential in medical scenarios. However, their safety and robustness remain unresolved. This study performs a comprehensive evaluation on adversarial attack methods to identify and…

Cryptography and Security · Computer Science 2025-08-11 Peizhuo Liu

Machine learning algorithms can be fooled by small well-designed adversarial perturbations. This is reminiscent of cellular decision-making where ligands (called antagonists) prevent correct signalling, like in early immune recognition. We…

Biological Physics · Physics 2019-07-31 Thomas J. Rademaker , Emmanuel Bengio , Paul François

Alzheimer's disease (AD) is the fifth-leading cause of death among Americans aged 65 and older. Screening and early detection of AD and related dementias (ADRD) are critical for timely intervention and for identifying clinical trial…

Artificial Intelligence · Computer Science 2024-05-29 Jiankun Wang , Sumyeong Ahn , Taykhoom Dalal , Xiaodan Zhang , Weishen Pan , Qiannan Zhang , Bin Chen , Hiroko H. Dodge , Fei Wang , Jiayu Zhou

Large-scale finite element simulations of complex physical systems governed by partial differential equations (PDE) crucially depend on adaptive mesh refinement (AMR) to allocate computational budget to regions where higher resolution is…

Peptide classification tasks, such as predicting toxicity and HIV inhibition, are fundamental to bioinformatics and drug discovery. Traditional approaches rely heavily on handcrafted encodings of one-dimensional (1D) peptide sequences,…

Artificial Intelligence · Computer Science 2025-11-14 Vincent Schilling , Akshat Dubey , Georges Hattab