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Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…
We study a machine learning (ML) technique for refining images acquired during in situ observation using liquid-cell transmission electron microscopy (LC-TEM). Our model is constructed using a U-Net architecture and a ResNet encoder. For…
Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…
Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…
Estimating what would be an individual's potential response to varying levels of exposure to a treatment is of high practical relevance for several important fields, such as healthcare, economics and public policy. However, existing methods…
Simulating the dynamics of ions near polarizable nanoparticles (NPs) using coarse-grained models is extremely challenging due to the need to solve the Poisson equation at every simulation timestep. Recently, a molecular dynamics (MD) method…
Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…
Background:Convolutional Neural Networks(CNN) and Vision Transformers(ViT) are the main techniques used in Medical image segmentation. However, CNN is limited to local contextual information, and ViT's quadratic complexity results in…
Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…
We study the propagation of nucleons and nuclei in tissue-like media within a Monte Carlo Model for Heavy-ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.2). The model takes into account fragmentation of projectile nuclei and…
Estimating the uncertainty of deep learning models in a reliable and efficient way has remained an open problem, where many different solutions have been proposed in the literature. Most common methods are based on Bayesian approximations,…
Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…
Convolutional neural networks (CNNs) and Transformer-based models are being widely applied in medical image segmentation thanks to their ability to extract high-level features and capture important aspects of the image. However, there is…
To accurately study chemical reactions in the condensed phase or within enzymes, both a quantum-mechanical description and sufficient configurational sampling is required to reach converged estimates. Here, quantum mechanics/molecular…
Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at…
Background. Absorbed radiation dose to the mandible is an important risk factor in the development of mandibular osteoradionecrosis (ORN) in head and neck cancer (HNC) patients treated with radiotherapy (RT). The prediction of mandibular…
We address the degree to which machine learning can be used to accurately and transferably predict post-Hartree-Fock correlation energies. Refined strategies for feature design and selection are presented, and the molecular-orbital-based…
We used the GEANT4 Monte Carlo MC Toolkit to simulate carbon ion beams incident on water, tissue, and bone, taking into account nuclear fragmentation reactions. Upon increasing the energy of the primary beam, the position of the Bragg-Peak…
Cardiac magnetic resonance (CMR) imaging is widely used to visualise cardiac motion and diagnose heart disease. However, standard CMR imaging requires patients to lie still in a confined space inside a loud machine for 40-60 min, which…
Radio-frequency dosimetry is an important process in human safety and for compliance of related products. Recently, computational human models generated from medical images have often been used for such assessment, especially to consider…