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Spatial transcriptomics enables genome-wide expression analysis within native tissue context, yet identifying spatial domains remains challenging due to complex gene-spatial interactions. Existing methods typically process spatial and…

Machine Learning · Computer Science 2025-12-19 Jianping Mei , Siqi Ai , Ye Yuan

Masked Image Modeling (MIM) is a promising self-supervised learning approach that enables learning from unlabeled images. Despite its recent success, learning good representations through MIM remains challenging because it requires…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Amir Bar , Florian Bordes , Assaf Shocher , Mahmoud Assran , Pascal Vincent , Nicolas Ballas , Trevor Darrell , Amir Globerson , Yann LeCun

Masked Image Modeling (MIM) has emerged as a promising method for deriving visual representations from unlabeled image data by predicting missing pixels from masked portions of images. It excels in region-aware learning and provides strong…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Yibing Wei , Abhinav Gupta , Pedro Morgado

While supervised learning has enabled great progress in many applications, unsupervised learning has not seen such widespread adoption, and remains an important and challenging endeavor for artificial intelligence. In this work, we propose…

Machine Learning · Computer Science 2019-01-23 Aaron van den Oord , Yazhe Li , Oriol Vinyals

Currently, under supervised learning, a model pretrained by a large-scale nature scene dataset and then fine-tuned on a few specific task labeling data is the paradigm that has dominated the knowledge transfer learning. It has reached the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Tong Zhang , Peng Gao , Hao Dong , Yin Zhuang , Guanqun Wang , Wei Zhang , He Chen

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Temporally aware image representations are crucial for capturing disease progression in 3D volumes of longitudinal medical datasets. However, recent state-of-the-art self-supervised learning approaches like Masked Autoencoding (MAE),…

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Context-aware methods have achieved remarkable advancements in supervised scene text recognition by leveraging semantic priors from words. Considering the heterogeneity of text and background in STR, we propose that such contextual priors…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Tiancheng Lin , Jinglei Zhang , Yi Xu , Kai Chen , Rui Zhang , Chang-Wen Chen

Learning representations through self-supervision on unlabeled data has proven highly effective for understanding diverse images. However, remote sensing images often have complex and densely populated scenes with multiple land objects and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Mingming Zhang , Qingjie Liu , Yunhong Wang

Existing self-supervised learning (SSL) methods primarily learn object-invariant representations but often neglect the spatial structure and relationships among object parts. To address this limitation, we introduce Spatial Prediction (SP),…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yang Shen , Yusen Cai , Weronika Hryniewska-Guzik , Qing Lin , Mengmi Zhang

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Huai Chen , Renzhen Wang , Xiuying Wang , Jieyu Li , Qu Fang , Hui Li , Jianhao Bai , Qing Peng , Deyu Meng , Lisheng Wang

This paper proposes an unsupervised method for learning a unified representation that serves both discriminative and generative purposes. While most existing unsupervised learning approaches focus on a representation for only one of these…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Shengbang Tong , Xili Dai , Yubei Chen , Mingyang Li , Zengyi Li , Brent Yi , Yann LeCun , Yi Ma

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

Applications · Statistics 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Hyperspectral images (HSIs) capture rich spectral signatures that reveal vital material properties, offering broad applicability across various domains. However, the scarcity of labeled HSI data limits the full potential of deep learning,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Shaheer Mohamed , Tharindu Fernando , Sridha Sridharan , Peyman Moghadam , Clinton Fookes

Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Qianying Liu , Xiao Gu , Paul Henderson , Fani Deligianni

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

Recent advancements in text-to-image generation have inspired researchers to generate datasets tailored for perception models using generative models, which prove particularly valuable in scenarios where real-world data is limited. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Minho Park , Sunghyun Park , Jooyeol Yun , Jaegul Choo

"Is it possible to predict expression levels of different genes at a given spatial location in the routine histology image of a tumor section by modeling its stain absorption characteristics?" In this work, we propose a "stain-aware"…

Image and Video Processing · Electrical Eng. & Systems 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas
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