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Geo-tagged images are publicly available in large quantities, whereas labels such as object classes are rather scarce and expensive to collect. Meanwhile, contrastive learning has achieved tremendous success in various natural image and…
While image-text representation learning has become very popular in recent years, existing models tend to lack spatial awareness and have limited direct applicability for dense understanding tasks. For this reason, self-supervised…
Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…
Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…
Most existing text recognition methods are trained on large-scale synthetic datasets due to the scarcity of labeled real-world datasets. Synthetic images, however, cannot faithfully reproduce real-world scenarios, such as uneven…
Spatial transcriptomics (ST) maps gene expression within tissue at individual spots, making it a valuable resource for multimodal representation learning. Additionally, ST inherently contains rich hierarchical information both across and…
While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…
Inspired by the great success of language model (LM)-based pre-training, recent studies in visual document understanding have explored LM-based pre-training methods for modeling text within document images. Among them, pre-training that…
In an era where symbolic mathematical equations are indispensable for modeling complex natural phenomena, scientific inquiry often involves collecting observations and translating them into mathematical expressions. Recently, deep learning…
Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…
Spatial transcriptomics offers spatially resolved gene expression profiling within tissue sections, but its cost and limited throughput hinder large-scale deployment. To extend this capability to routine practice, recent computational…
Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to pathological features such as disease subtypes, it may…
With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…
Image pre-training, the current de-facto paradigm for a wide range of visual tasks, is generally less favored in the field of video recognition. By contrast, a common strategy is to directly train with spatiotemporal convolutional neural…
Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when…
A comprehensive understanding of vision and language and their interrelation are crucial to realize the underlying similarities and differences between these modalities and to learn more generalized, meaningful representations. In recent…
Compared to the prosperity of pre-training models in natural image understanding, the research on large-scale pre-training models for facial knowledge learning is still limited. Current approaches mainly rely on manually assembled and…
Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…
Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…
Image-text retrieval is a central problem for understanding the semantic relationship between vision and language, and serves as the basis for various visual and language tasks. Most previous works either simply learn coarse-grained…