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Gene regulation is central to understanding cellular processes and development, potentially leading to the discovery of new treatments for diseases and personalized medicine. Inferring gene regulatory networks (GRNs) from single-cell RNA…

Computational Engineering, Finance, and Science · Computer Science 2025-06-17 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

The Kolmogorov-Arnold Network (KAN) is a new network architecture known for its high accuracy in several tasks such as function fitting and PDE solving. The superior expressive capability of KAN arises from the Kolmogorov-Arnold…

Machine Learning · Computer Science 2024-12-19 Ruichen Qiu , Yibo Miao , Shiwen Wang , Lijia Yu , Yifan Zhu , Xiao-Shan Gao

Machine learning for scientific discovery is increasingly becoming popular because of its ability to extract and recognize the nonlinear characteristics from the data. The black-box nature of deep learning methods poses difficulties in…

Computational Physics · Physics 2024-11-19 Ashish Pal , Satish Nagarajaiah

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Survival analysis aims to model how covariates and time jointly shape the time-to-event distribution under right censoring. Classical methods such as the Cox model and generalised additive models (GAMs) require interactions and time-varying…

Machine Learning · Statistics 2026-05-26 Stelios Boulitsakis Logothetis , Angela Wood , Pietro Liò

For many real-world applications, understanding feature-outcome relationships is as crucial as achieving high predictive accuracy. While traditional neural networks excel at prediction, their black-box nature obscures underlying functional…

Machine Learning · Computer Science 2025-10-03 Wangxuan Fan , Ching Wang , Siqi Li , Nan Liu

Kolmogorov-Arnold Networks (KANs) represent an innovation in neural network architectures, offering a compelling alternative to Multi-Layer Perceptrons (MLPs) in models such as Convolutional Neural Networks (CNNs), Recurrent Neural Networks…

Machine Learning · Computer Science 2025-02-12 Hoang-Thang Ta , Duy-Quy Thai , Anh Tran , Grigori Sidorov , Alexander Gelbukh

Interpretable representations are the backbone of many explainers that target black-box predictive systems based on artificial intelligence and machine learning algorithms. They translate the low-level data representation necessary for good…

Machine Learning · Computer Science 2024-04-29 Kacper Sokol , Peter Flach

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Image-to-Image translation in Generative Artificial Intelligence (Generative AI) has been a central focus of research, with applications spanning healthcare, remote sensing, physics, chemistry, photography, and more. Among the numerous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Arpan Mahara , Naphtali D. Rishe , Liangdong Deng

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Hyperspectral image classification is a crucial but challenging task due to the high dimensionality and complex spatial-spectral correlations inherent in hyperspectral data. This paper employs Wavelet-based Kolmogorov-Arnold Network…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Seyd Teymoor Seydi , Zavareh Bozorgasl , Hao Chen

The demand for open and trustworthy AI models points towards widespread publishing of model weights. Consumers of these model weights must be able to act accordingly with the information provided. That said, one of the simplest AI…

Machine Learning · Computer Science 2024-06-21 Danial Dervovic , Freddy Lécué , Nicolás Marchesotti , Daniele Magazzeni

Kolmogorov-Arnold Networks (KANs) have emerged as a promising alternative to Multi-layer Perceptrons (MLPs) due to their superior function-fitting abilities in data-driven modeling. In this paper, we propose a novel framework, DAE-KAN, for…

Machine Learning · Computer Science 2025-04-24 Kai Luo , Juan Tang , Mingchao Cai , Xiaoqing Zeng , Manqi Xie , Ming Yan

Credit scoring is a high-stakes task in financial services, where model decisions directly impact individuals' access to credit and are subject to strict regulatory scrutiny. While Quantum Machine Learning (QML) offers new computational…

Machine Learning · Computer Science 2026-02-12 Abdul Samad Khan , Nouhaila Innan , Aeysha Khalique , Muhammad Shafique

Graph contrastive learning (GCL) has demonstrated great promise for learning generalizable graph representations from unlabeled data. However, conventional GCL approaches face two critical limitations: (1) the restricted expressive capacity…

Machine Learning · Computer Science 2025-08-11 Zihu Wang , Boxun Xu , Hejia Geng , Peng Li

The Kolmogorov-Arnold Network (KAN) is a novel multi-layer network model recognized for its efficiency in neuromorphic computing, where synapses between neurons are trained linearly. Computations in KAN are performed by generating a…

Quantum Physics · Physics 2025-12-19 Hikaru Wakaura , Rahmat Mulyawan , Andriyan B. Suksmono

Interpretability of learning-to-rank models is a crucial yet relatively under-examined research area. Recent progress on interpretable ranking models largely focuses on generating post-hoc explanations for existing black-box ranking models,…

Prediction of survival in patients diagnosed with a brain tumour is challenging because of heterogeneous tumour behaviours and responses to treatment. Better estimations of prognosis would support treatment planning and patient support.…

Machine Learning · Computer Science 2021-06-18 Colleen E. Charlton , Michael Tin Chung Poon , Paul M. Brennan , Jacques D. Fleuriot

Modern machine learning, grounded in the Universal Approximation Theorem, has achieved significant success in the study of phase transitions in both equilibrium and non-equilibrium systems. However, identifying the critical points of…

Statistical Mechanics · Physics 2025-03-25 Dian Xu , Shanshan Wang , Wei Li , Weibing Deng , Feng Gao , Jianmin Shen
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