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Despite the immense potential of AI-powered medical devices to revolutionize healthcare, concerns regarding their safety in life-critical applications remain. While the European regulatory framework provides a comprehensive approach to…

Software Engineering · Computer Science 2024-09-13 Tuomas Granlund , Vlad Stirbu , Tommi Mikkonen

Autonomous UI agents powered by AI have tremendous potential to boost human productivity by automating routine tasks such as filing taxes and paying bills. However, a major challenge in unlocking their full potential is security, which is…

Cryptography and Security · Computer Science 2025-05-20 Ivan Evtimov , Arman Zharmagambetov , Aaron Grattafiori , Chuan Guo , Kamalika Chaudhuri

UL 4600, the safety standard for autonomous products, mandates the use of Safety Performance Indicators (SPIs) to continuously ensure the validity of safety cases by monitoring and taking action when violations are identified. Despite…

Software Engineering · Computer Science 2024-10-02 Daniel Ratiu , Tihomir Rohlinger , Torben Stolte , Stefan Wagner

A major concern amongst AI safety practitioners is the possibility of loss of control, whereby humans lose the ability to exert control over increasingly advanced AI systems. The range of concerns is wide, spanning current day risks to…

Computers and Society · Computer Science 2026-02-04 Steve Barrett , Anna Bruvere , Sean P. Fillingham , Catherine Rhodes , Stefano Vergani

Humanoid robots are difficult to deploy safely because they have high-dimensional bodies, many collision constraints, and must operate near people and obstacles. Safety filters help by modifying a nominal control action when it may violate…

Robotics · Computer Science 2026-05-20 Saurav Ghosh , Abdou Sow , Luke Zhang

Ensuring the safety and reliability of Automated Driving Systems (ADS) remains a critical challenge, as traditional verification methods such as large-scale on-road testing are prohibitively costly and time-consuming.To address…

Software Engineering · Computer Science 2025-12-18 Ji Zhou , Yongqi Zhao , Yixian Hu , Hexuan Li , Zhengguo Gu , Nan Xu , Arno Eichberger

Autonomous vehicles (AV) depend on the sensors like RADAR and camera for the perception of the environment, path planning, and control. With the increasing autonomy and interactions with the complex environment, there have been growing…

Systems and Control · Computer Science 2021-06-22 Abu Hasnat Mohammad Rubaiyat , Yongming Qin , Homa Alemzadeh

Drivers are becoming increasingly reliant on advanced driver assistance systems (ADAS) as autonomous driving technology becomes more popular and developed with advanced safety features to enhance road safety. However, the increasing…

Cryptography and Security · Computer Science 2025-06-23 Cheng Chen , Grant Xiao , Daehyun Lee , Lishan Yang , Evgenia Smirni , Homa Alemzadeh , Xugui Zhou

The transition to the smart grid introduces complexity to the design and operation of electric power systems. This complexity has the potential to result in safety-related losses that are caused, for example, by unforeseen interactions…

Software Engineering · Computer Science 2023-09-15 Paul Smith , Eva Piatkowska , Edmund Widl , Filip Pröstl Andrén , Thomas I. Strasser

Critical software systems face stringent requirements in safety, security, and reliability due to the circumstances surrounding their operation. Safety and security have progressively gained importance over the years due to the integration…

Software Engineering · Computer Science 2015-12-16 Julio Escribano-Barreno , Marisol García-Valls

Artificial Knowledge (AK) systems are transforming decision-making across critical domains such as healthcare, finance, and criminal justice. However, their growing opacity presents governance challenges that current regulatory approaches,…

Computers and Society · Computer Science 2025-05-29 Dalit Ken-Dror Feldman , Daniel Benoliel

Improving patient care safety is an ultimate objective for medical cyber-physical systems. A recent study shows that the patients' death rate can be significantly reduced by computerizing medical best practice guidelines. To facilitate the…

Software Engineering · Computer Science 2018-11-05 Chunhui Guo , Zhicheng Fu , Zhenyu Zhang , Shangping Ren , Lui Sha

The safety and clinical effectiveness of medical devices are closely associated with their specific use in clinical treatments. Assuring safety and the desired clinical effectiveness is challenging. Different people may react differently to…

Computers and Society · Computer Science 2023-02-17 Spencer Deevy , Tiago de Moraes Machado , Amen Modhafar , Wesley O'Beirne , Richard Paige , Alan Wassyng

The current verification flow of complex systems uses different engines synergistically: virtual prototyping, formal verification, simulation, emulation and FPGA prototyping. However, none is able to verify a complete architecture.…

Logic in Computer Science · Computer Science 2018-02-12 Tomas Grimm , Djones Lettnin , Michael Hübner

We present an overview of recently developed data-driven tools for safety analysis of autonomous vehicles and advanced driver assist systems. The core algorithms combine model-based, hybrid system reachability analysis with sensitivity…

Systems and Control · Computer Science 2017-04-24 Chuchu Fan , Bolun Qi , Sayan Mitra

Autonomous robots deployed in shared human environments, such as agricultural settings, require rigorous safety assurance to meet both functional reliability and regulatory compliance. These systems must operate in dynamic, unstructured…

Robotics · Computer Science 2025-10-16 Mustafa Adam , David A. Anisi , Pedro Ribeiro

Autonomous driving promises safer roads, reduced congestion, and improved mobility, yet validating these systems across diverse conditions remains a major challenge. Real-world testing is expensive, time-consuming, and sometimes unsafe,…

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks.…

Machine Learning · Computer Science 2025-06-10 Yishan Shen , Yuyang Ye , Hui Xiong , Yong Chen

As autonomous systems (AS) increasingly become part of our daily lives, ensuring their trustworthiness is crucial. In order to demonstrate the trustworthiness of an AS, we first need to specify what is required for an AS to be considered…

Verification of complex, safety-critical systems is a significant challenge. Manual testing and simulations are often used, but are only capable of exploring a subset of the system's reachable states. Formal methods are mathematically-based…

Software Engineering · Computer Science 2021-10-19 Matt Luckcuck , Marie Farrell , Oisín Sheridan , Rosemary Monahan