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A dynamic treatment regimen (DTR) is a pre-specified sequence of decision rules which maps baseline or time-varying measurements on an individual to a recommended intervention or set of interventions. Sequential multiple assignment…

Methodology · Statistics 2019-10-23 Brook Luers , Min Qian , Inbal Nahum-Shani , Connie Kasari , Daniel Almirall

Online planning in Markov Decision Processes (MDPs) enables agents to make sequential decisions by simulating future trajectories from the current state, making it well-suited for large-scale or dynamic environments. Sample-based methods…

Artificial Intelligence · Computer Science 2025-09-22 Tamir Shazman , Idan Lev-Yehudi , Ron Benchetit , Vadim Indelman

We explore the statistical and economic importance of restrictions on the dynamics of risk compensation from the perspective of a real-time Bayesian learner who predicts bond excess returns using dynamic term structure models (DTSMs). The…

Dynamic data selection aims to accelerate training with lossless performance. However, reducing training data inherently limits data diversity, potentially hindering generalization. While data augmentation is widely used to enhance…

Machine Learning · Computer Science 2025-05-13 Suorong Yang , Peng Ye , Furao Shen , Dongzhan Zhou

Composite endpoints are widely used in cardiovascular clinical trials to improve statistical efficiency while preserving clinical relevance. The Win Ratio (WR) measure and more general frameworks of Win Statistics have emerged as…

Methodology · Statistics 2025-11-24 Yunhan Mou , Fan Li , Denise Esserman , Yuan Huang

Scenario reduction (SR) aims to identify a small yet representative scenario set to depict the underlying uncertainty, which is critical to scenario-based stochastic optimization (SBSO) of power systems. Existing SR techniques commonly aim…

Optimization and Control · Mathematics 2025-06-16 Yingrui Zhuang , Lin Cheng , Ning Qi , Mads R. Almassalkhi , Feng Liu

Optimization-based samplers such as randomize-then-optimize (RTO) [2] provide an efficient and parallellizable approach to solving large-scale Bayesian inverse problems. These methods solve randomly perturbed optimization problems to draw…

Computation · Statistics 2019-10-29 Johnathan Bardsley , Tiangang Cui , Youssef Marzouk , Zheng Wang

Self-supervised representation learning (SSRL) has demonstrated remarkable empirical success, yet its underlying principles remain insufficiently understood. While recent works attempt to unify SSRL methods by examining their…

Machine Learning · Computer Science 2025-10-03 Akhlaqur Rahman Sabby , Yi Sui , Tongzi Wu , Jesse C. Cresswell , Ga Wu

Recent advances in large language models (LLMs) have sparked growing interest in automatic RTL optimization for better performance, power, and area (PPA). However, existing methods are still far from realistic RTL optimization. Their…

Artificial Intelligence · Computer Science 2026-04-28 Wenji Fang , Yao Lu , Shang Liu , Jing Wang , Ziyan Guo , Junxian He , Fengbin Tu , Zhiyao Xie

Effective decision-making in Large Language Models (LLMs) is essential for handling intricate tasks. However, existing approaches prioritize performance but often overlook the balance between effectiveness and computational cost. To address…

Computation and Language · Computer Science 2025-06-03 Jiawei Gu , Shangsong Liang

Conventional deep network training generally optimizes all samples under a largely uniform learning paradigm, without explicitly modeling the heterogeneous competition among them. Such an oversimplified treatment can lead to several…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Ying Zheng , Yiyi Zhang , Yi Wang , Lap-Pui Chau

Computational capability often falls short when confronted with massive data, posing a common challenge in establishing a statistical model or statistical inference method dealing with big data. While subsampling techniques have been…

Methodology · Statistics 2024-10-31 Yixiao Ruan , Zan Li , Zhaohui Li , Dennis K. J. Lin , Qingpei Hu , Dan Yu

Spectral inference provides fast algorithms and provable optimality for latent topic analysis. But for real data these algorithms require additional ad-hoc heuristics, and even then often produce unusable results. We explain this poor…

Machine Learning · Computer Science 2016-11-02 Moontae Lee , David Bindel , David Mimno

Medical decision-making makes frequent use of algorithms that combine risk equations with rules, providing clear and standardized treatment pathways. Symbolic regression (SR) traditionally limits its search space to continuous function…

Computation of sample size is important when designing clinical trials. The presence of competing risks makes the design of clinical trials with time-to-event endpoints cumbersome. A model based on the subdistribution hazard ratio (SHR) is…

Methodology · Statistics 2023-11-22 Xiang Geng , Zhaojin Li , Chengfeng Zhang , Yanjie Wang , Haoning Shen , Zhiheng Huang , Yawen Hou , Zheng Chen

Adaptive radiation therapy (ART) seeks to maintain accurate dose delivery by monitoring anatomical changes during treatment and modifying plans accordingly, yet commonly used approaches for estimating cumulative dose rely on heuristic,…

Medical Physics · Physics 2026-03-03 Robert Boyd , Wolfgang A. Tomé

Large language models (LLMs) suffer from catastrophic forgetting during continual learning. Conventional rehearsal-based methods rely on previous training data to retain the model's ability, which may not be feasible in real-world…

Computation and Language · Computer Science 2024-05-28 Jianheng Huang , Leyang Cui , Ante Wang , Chengyi Yang , Xinting Liao , Linfeng Song , Junfeng Yao , Jinsong Su

Stochastic processes wherein the size of the state space is changing as a function of time offer models for the emergence of scale-invariant features observed in complex systems. I consider such a sample-space reducing (SSR) stochastic…

Statistical Mechanics · Physics 2016-05-04 Avinash Chand Yadav

The scaling of Large Multimodal Models (LMMs) is constrained by the quality-quantity trade-off inherent in synthetic data. Previous approaches, such as LLM-as-a-Judge, have proven their effectiveness in addressing this but suffer from…

Artificial Intelligence · Computer Science 2026-05-11 Jinhao Jing , Qiannian Zhao , Chao Huang , Zhan Su

Sparsity in Deep Neural Networks (DNNs) is studied extensively with the focus of maximizing prediction accuracy given an overall parameter budget. Existing methods rely on uniform or heuristic non-uniform sparsity budgets which have…

Machine Learning · Computer Science 2020-06-24 Aditya Kusupati , Vivek Ramanujan , Raghav Somani , Mitchell Wortsman , Prateek Jain , Sham Kakade , Ali Farhadi
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