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The apparent stochasticity of in-vivo neural circuits has long been hypothesized to represent a signature of ongoing stochastic inference in the brain. More recently, a theoretical framework for neural sampling has been proposed, which…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Ilja Bytschok , Johannes Bill , Johannes Schemmel , Karlheinz Meier

Real-time synthesis of legged locomotion maneuvers in challenging industrial settings is still an open problem, requiring simultaneous determination of footsteps locations several steps ahead while generating whole-body motions close to the…

Increasingly stringent throughput requirements in the industry necessitate the need for lightweight design of high-precision motion systems to allow for high accelerations, while still achieving accurate positioning of the moving-body. The…

Systems and Control · Electrical Eng. & Systems 2022-09-20 Yorick Broens , Hans Butler , Roland Tóth

Deep Brain Stimulation (DBS) is a well-established neurosurgical treatment aiming at symptom alleviation in a range of neurological and psychiatric diseases. Computational models of DBS are widely used to investigate the effects of…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Anna Franziska Frigge , Alexander Medvedev

We introduce a discrete linear lossy system with an embedded "hot spot" (HS), i.e., a site carrying linear gain and complex cubic nonlinearity. The system can be used to model an array of optical or plasmonic waveguides, where selective…

Optics · Physics 2016-11-26 Boris A. Malomed , Edwin Ding , K. W. Chow , S. K. Lai

We consider the problem of sampling transition paths between two given metastable states of a molecular system, e.g. a folded and unfolded protein or products and reactants of a chemical reaction. Due to the existence of high energy…

Biomolecules · Quantitative Biology 2023-07-19 Lars Holdijk , Yuanqi Du , Ferry Hooft , Priyank Jaini , Bernd Ensing , Max Welling

We embed a spiking cerebellar model within an adaptive real-time (RT) control loop that is able to operate a real robotic body (iCub) when performing different vestibulo-ocular reflex (VOR) tasks. The spiking neural network computation,…

Neurons and Cognition · Quantitative Biology 2020-04-01 Francisco Naveros , Niceto R. Luque , Eduardo Ros , Angelo Arleo

The centimeter-scale cyborg insects have a potential advantage for application in narrow environments where humans cannot operate. To realize such tasks, researchers have developed a small printed-circuit-board (PCB) which an insect can…

Robotics · Computer Science 2024-10-11 Kazuki Kai , Le Duc Long , Hirotaka Sato

We introduce the notion of importance sampling under embedded barrier state control, titled Safety Controlled Model Predictive Path Integral Control (SC-MPPI). For robotic systems operating in an environment with multiple constraints, hard…

Systems and Control · Electrical Eng. & Systems 2023-03-08 Manan Gandhi , Hassan Almubarak , Evangelos Theodorou

Accurate modeling of system dynamics holds intriguing potential in broad scientific fields including cytodynamics and fluid mechanics. This task often presents significant challenges when (i) observations are limited to cross-sectional…

Machine Learning · Computer Science 2024-02-19 Yuning You , Ruida Zhou , Yang Shen

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

Neurons and Cognition · Quantitative Biology 2017-10-17 Songting Li , Nan Liu , Xiaohui Zhang , Douglas Zhou , David Cai

Due to the limited connectivity of gate model quantum devices, logical quantum circuits must be compiled to target hardware before they can be executed. Often, this process involves the insertion of SWAP gates into the logical circuit,…

Quantum Physics · Physics 2023-06-16 Kyle E. C. Booth

Seasonal patterns of the incidence, hospital visits, and mortality of ischemic heart disease (IHD) have been widely reported. This study aims to investigate seasonal and periodic patterns of IHD hospitalizations in New York using a novel…

Applications · Statistics 2025-09-05 Yineng Chen , Edward Valachovic

Accurate modeling of power flow behavior is essential for a wide range of power system applications, yet the nonlinear and nonconvex structure of the underlying equations often limits their direct use in large-scale optimization problems.…

Systems and Control · Electrical Eng. & Systems 2026-03-17 Paprapee Buason , Sidhant Misra , Daniel K. Molzahn

Cardiac resynchronization therapy (CRT) is a treatment that is used to compensate for irregularities in the heartbeat. Studies have shown that this treatment is more effective in heart patients with left bundle branch block (LBBB)…

Signal Processing · Electrical Eng. & Systems 2023-06-27 Alireza Sadeghi , Alireza Rezaee , Farshid Hajati

Left ventricular assist devices (LVADs) are mechanical pumps, which can be used to support heart failure (HF) patients as bridge to transplant and destination therapy. To automatically adjust the LVAD speed, a physiological control system…

Systems and Control · Electrical Eng. & Systems 2021-05-04 Masoud Fetanat , Michael Stevens , Christopher Hayward , Nigel H. Lovell

We demonstrate an effective control of nonlinear interactions of lasing modes in a semiconductor microdisk cavity by shaping the pump profile. A target mode is selected at the expense of its competing modes either by increasing their lasing…

Optics · Physics 2016-02-18 Seng Fatt Liew , Li Ge , Brandon Redding , Glenn S. Solomon , Hui Cao

This paper introduces a learning-based control framework for a soft robotic actuator system designed to modulate intracranial pressure (ICP) waveforms, which is essential for studying cerebrospinal fluid dynamics and pathological processes…

Probabilistic shaping (PS) has attracted significant attention in intensity-modulation and direct-detection (IM-DD) systems. However, due to the unique system model and inherent constraints, the effective application of the PS technique is…

Signal Processing · Electrical Eng. & Systems 2025-07-25 Dongdong Zou , Wei Wang , Jiawen Yao , Zhongxing Tian , Zeyu Feng , Huan Huang , Fan Li , Gordon Ning Liu , Gangxiang Shen , Yi Cai

We study the inverse problem of tuning interaction parameters between charged colloidal particles interacting with a hard-core repulsive Yukawa potential, so that they assemble into specified crystal structures. Here, we target the…

Soft Condensed Matter · Physics 2019-10-02 Rajneesh Kumar , Gabriele M. Coli , Marjolein Dijkstra , Srikanth Sastry