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Automatic ICD coding from clinical text is a critical task in medical NLP but remains hindered by the extreme long-tail distribution of diagnostic codes. Thousands of rare and zero-shot ICD codes are severely underrepresented in datasets…

Computation and Language · Computer Science 2025-11-19 Truong Vo , Weiyi Wu , Kaize Ding

Knowledge distillation (KD) represents a vital mechanism to transfer expertise from complex teacher networks to efficient student models. However, in decentralized or secure AI ecosystems, privacy regulations and proprietary interests often…

Machine Learning · Computer Science 2026-04-29 Tri-Nhan Vo , Dang Nguyen , Trung Le , Kien Do , Sunil Gupta

In differential privacy (DP), a challenging problem is to generate synthetic datasets that efficiently capture the useful information in the private data. The synthetic dataset enables any task to be done without privacy concern and…

Cryptography and Security · Computer Science 2021-01-01 Zhikun Zhang , Tianhao Wang , Ninghui Li , Jean Honorio , Michael Backes , Shibo He , Jiming Chen , Yang Zhang

Synthetic Data Generation (SDG) based on Artificial Intelligence (AI) can transform the way clinical medicine is delivered by overcoming privacy barriers that currently render clinical data sharing difficult. This is the key to accelerating…

Simulation is increasingly being used for generating large labelled datasets in many machine learning problems. Recent methods have focused on adjusting simulator parameters with the goal of maximising accuracy on a validation task, usually…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Harkirat Singh Behl , Atılım Güneş Baydin , Ran Gal , Philip H. S. Torr , Vibhav Vineet

There is a growing need for flexible general frameworks that integrate individual-level data with external summary information for improved statistical inference. External information relevant for a risk prediction model may come in…

Methodology · Statistics 2023-04-11 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

We propose dpmm, an open-source library for synthetic data generation with Differentially Private (DP) guarantees. It includes three popular marginal models -- PrivBayes, MST, and AIM -- that achieve superior utility and offer richer…

Cryptography and Security · Computer Science 2025-06-03 Sofiane Mahiou , Amir Dizche , Reza Nazari , Xinmin Wu , Ralph Abbey , Jorge Silva , Georgi Ganev

Currently, it is ever more common to access online services for activities which formerly required physical attendance. From banking operations to visa applications, a significant number of processes have been digitised, especially since…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Daniel Benalcazar , Juan E. Tapia , Sebastian Gonzalez , Christoph Busch

How can we release a massive volume of sensitive data while mitigating privacy risks? Privacy-preserving data synthesis enables the data holder to outsource analytical tasks to an untrusted third party. The state-of-the-art approach for…

Machine Learning · Computer Science 2022-03-08 Shun Takagi , Tsubasa Takahashi , Yang Cao , Masatoshi Yoshikawa

Creation of synthetic data models has represented a significant advancement across diverse scientific fields, but this technology also brings important privacy considerations for users. This work focuses on enhancing a non-parametric…

Data plays a fundamental role in consolidating markets, services, and products in the digital financial ecosystem. However, the use of real data, especially in the financial context, can lead to privacy risks and access restrictions,…

Small longitudinal clinical cohorts, common in maternal health, rare diseases, and early-phase trials, limit computational modeling: too few patients to train reliable models, yet too costly and slow to expand through additional enrollment.…

Machine Learning · Computer Science 2026-04-10 Jeffrey D. Varner , Maria Cristina Bravo , Carole McBride , Thomas Orfeo , Ira Bernstein

When machine learning models are trained on synthetic data and then deployed on real data, there is often a performance drop due to the distribution shift between synthetic and real data. In this paper, we introduce a new ensemble strategy…

Cryptography and Security · Computer Science 2023-10-17 Haoyuan Sun , Navid Azizan , Akash Srivastava , Hao Wang

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

We propose the approach of model-based differentially private synthesis (modips) in the Bayesian framework for releasing individual-level surrogate/synthetic datasets with privacy guarantees given the original data. The modips technique…

Methodology · Statistics 2021-04-27 Fang Liu

Differential privacy (DP) has been accepted as a rigorous criterion for measuring the privacy protection offered by random mechanisms used to obtain statistics or, as we will study here, synthetic datasets from confidential data. Methods to…

Methodology · Statistics 2024-05-09 Leila Nombo , Anne-Sophie Charest

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Protecting user data privacy can be achieved via many methods, from statistical transformations to generative models. However, all of them have critical drawbacks. For example, creating a transformed data set using traditional techniques is…

Machine Learning · Computer Science 2024-04-24 Tânia Carvalho , Nuno Moniz , Luís Antunes , Nitesh Chawla