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Related papers: EHR-MCP: Real-world Evaluation of Clinical Informa…

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Enhancing clinical decision support (CDS), reducing documentation burdens, and improving patient health literacy remain persistent challenges in digital health. This paper presents an open-source, agent-based framework that integrates Large…

Software Engineering · Computer Science 2025-06-18 Abul Ehtesham , Aditi Singh , Saket Kumar

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large Language Models (LLMs) with tool-calling capabilities have demonstrated remarkable potential in executing complex tasks through external tool integration. The Model Context Protocol (MCP) has emerged as a standardized framework for…

Software Engineering · Computer Science 2026-03-24 Sarat Mudunuri , Jian Wan , Ally Qin , Srinivasan Manoharan

The Model Context Protocol (MCP) enables large language models (LLMs) to access external resources on demand. While commonly assumed to enhance performance, how LLMs actually leverage this capability remains poorly understood. We introduce…

Artificial Intelligence · Computer Science 2025-08-19 Wei Song , Haonan Zhong , Ziqi Ding , Jingling Xue , Yuekang Li

Model Context Protocol (MCP) servers contain a collection of thousands of open-source standardized tools, linking LLMs to external systems; however, existing datasets and benchmarks lack realistic, human-like user queries, remaining a…

Artificial Intelligence · Computer Science 2026-03-02 Shubh Laddha , Lucas Changbencharoen , Win Kuptivej , Surya Shringla , Archana Vaidheeswaran , Yash Bhaskar

The Model Context Protocol has emerged as a transformative standard for connecting large language models to external data sources and tools, rapidly gaining adoption across major AI providers and development platforms. However, existing…

Artificial Intelligence · Computer Science 2025-08-21 Ziyang Luo , Zhiqi Shen , Wenzhuo Yang , Zirui Zhao , Prathyusha Jwalapuram , Amrita Saha , Doyen Sahoo , Silvio Savarese , Caiming Xiong , Junnan Li

Healthcare AI systems have historically faced challenges in merging contextual reasoning, long-term state management, and human-verifiable workflows into a cohesive framework. This paper introduces a completely innovative architecture and…

Artificial Intelligence · Computer Science 2025-12-08 Zag ElSayed , Craig Erickson , Ernest Pedapati

Model Context Protocol (MCP) has recently gained increased attention within the AI community for providing a standardized way for large language models (LLMs) to interact with external tools and services, significantly enhancing their…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-12 Zihao Ding , Mufeng Zhu , Yao Liu

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

LLMs' capabilities are enhanced by using function calls to integrate various data sources or API results into the context window. Typical tools include search, web crawlers, maps, financial data, file systems, and browser usage, etc.…

Artificial Intelligence · Computer Science 2025-08-12 Shiqing Fan , Xichen Ding , Liang Zhang , Linjian Mo

Large Language Models (LLMs) demonstrate strong capabilities in solving complex tasks when integrated with external tools. The Model Context Protocol (MCP) has become a standard interface for enabling such tool-based interactions. However,…

Cryptography and Security · Computer Science 2026-01-23 Jiayi Fu , Yuansen Zhang , Yinggui Wang

As Large Language Models (LLMs) evolve from passive text generators to active reasoning agents capable of interacting with external tools, the Model Context Protocol (MCP) has emerged as a key standardized framework for dynamic tool…

Artificial Intelligence · Computer Science 2025-10-14 Xuanqi Gao , Siyi Xie , Juan Zhai , Shiqing Ma , Chao Shen

The integration of Large Language Models (LLMs) with Internet-of-Things (IoT) systems faces significant challenges in hardware heterogeneity and control complexity. The Model Context Protocol (MCP) emerges as a critical enabler, providing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-03 Ningyuan Yang , Guanliang Lyu , Mingchen Ma , Yiyi Lu , Yiming Li , Zhihui Gao , Hancheng Ye , Jianyi Zhang , Tingjun Chen , Yiran Chen

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Large language model (LLM)-powered agents are increasingly used to plan and execute scientific workflows, yet most research cyberinfrastructure (CI) exposes heterogeneous APIs and implements security models that present barriers for use by…

The Model Context Protocol (MCP) has been proposed as a unifying standard for connecting large language models (LLMs) with external tools and resources, promising the same role for AI integration that HTTP and USB played for the Web and…

Computers and Society · Computer Science 2025-11-18 Hechuan Guo , Yongle Hao , Yue Zhang , Minghui Xu , Peizhuo Lv , Jiezhi Chen , Xiuzhen Cheng

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Explicit modeling of capabilities and skills -- whether based on ontologies, Asset Administration Shells, or other technologies -- requires considerable manual effort and often results in representations that are not easily accessible to…

Software Engineering · Computer Science 2025-12-10 Luis Miguel Vieira da Silva , Aljosha Köcher , Felix Gehlhoff

The Model Context Protocol (MCP) (MCP Community, 2025) has emerged as a widely used framework for enabling LLM-based agents to communicate with external tools and services. The original MCP implementation (Anthropic, 2024) relies on a Large…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-26 Meenakshi Amulya Jayanti , X. Y. Han

Large Language Models (LLMs) increasingly rely on external tools to perform complex, realistic tasks, yet their ability to utilize the rapidly expanding Model Contextual Protocol (MCP) ecosystem remains limited. Existing MCP research covers…

Artificial Intelligence · Computer Science 2026-04-17 Wenhao Wang , Peizhi Niu , Zhao Xu , Zhaoyu Chen , Jian Du , Yaxin Du , Xianghe Pang , Keduan Huang , Yanfeng Wang , Qiang Yan , Siheng Chen
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