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Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…

Computation and Language · Computer Science 2026-04-28 Yimin Deng , Zhenxi Lin , Yejing Wang , Guoshuai Zhao , Pengyue Jia , Zichuan Fu , Derong Xu , Yefeng Zheng , Xiangyu Zhao , Li Zhu , Xian Wu , Xueming Qian

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Multimodal recommender systems leverage diverse data sources, such as user interactions, content features, and contextual information, to address challenges like cold-start and data sparsity. However, existing methods often suffer from one…

Information Retrieval · Computer Science 2026-02-24 Adamya Shyam , Venkateswara Rao Kagita , Bharti Rana , Vikas Kumar

Purpose High dimensional, multimodal data can nowadays be analyzed by huge deep neural networks with little effort. Several fusion methods for bringing together different modalities have been developed. Given the prevalence of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Christian Gapp , Elias Tappeiner , Martin Welk , Karl Fritscher , Elke Ruth Gizewski , Rainer Schubert

Multimodal clinical prediction faces three challenges: multiple foundation models (FMs) with complementary strengths per modality, pervasive missing modalities at training and test time, and sample-specific variation in modality…

Machine Learning · Computer Science 2026-05-19 Seungik Cho , Anqi Li , Wei Qiu

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Alvaro Lopez Pellicer , Plamen Angelov , Marwan Bukhari , Yi Li , Eduardo Soares , Jemma Kerns

The use of deep neural models for diagnosis prediction from clinical text has shown promising results. However, in clinical practice such models must not only be accurate, but provide doctors with interpretable and helpful results. We…

Medical imaging is a cornerstone of therapy and diagnosis in modern medicine. However, the choice of imaging modality for a particular theranostic task typically involves trade-offs between the feasibility of using a particular modality…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mayur Mallya , Ghassan Hamarneh

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Many healthcare applications are inherently multimodal, involving several physiological signals. As sensors for these signals become more common, improving machine learning methods for multimodal healthcare data is crucial. Pretraining…

Machine Learning · Computer Science 2024-10-23 Ching Fang , Christopher Sandino , Behrooz Mahasseni , Juri Minxha , Hadi Pouransari , Erdrin Azemi , Ali Moin , Ellen Zippi

Simultaneous functional PET/MR (sf-PET/MR) presents a cutting-edge multimodal neuroimaging technique. It provides an unprecedented opportunity for concurrently monitoring and integrating multifaceted brain networks built by spatiotemporally…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Luoyu Wang , Yitian Tao , Qing Yang , Yan Liang , Siwei Liu , Hongcheng Shi , Dinggang Shen , Han Zhang

Recent advances in large vision-language models (LVLMs) have demonstrated strong performance on general-purpose medical tasks. However, their effectiveness in specialized domains such as dentistry remains underexplored. In particular,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Jing Hao , Yuxuan Fan , Yanpeng Sun , Kaixin Guo , Lizhuo Lin , Jinrong Yang , Qi Yong H. Ai , Lun M. Wong , Hao Tang , Kuo Feng Hung

Pneumonia has been one of the fatal diseases and has the potential to result in severe consequences within a short period of time, due to the flow of fluid in lungs, which leads to drowning. If not acted upon by drugs at the right time,…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Can Jozef Saul , Deniz Yagmur Urey , Can Doruk Taktakoglu

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru
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