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In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

Numerical Analysis · Mathematics 2022-05-09 Harald Garcke , Dennis Trautwein

In this work, we develop a structure-preserving numerical scheme for a Cahn-Hilliard-Darcy model that describes tumor growth in a fluid-saturated porous medium. First, we derive a physically consistent model from the general framework…

Numerical Analysis · Mathematics 2026-05-22 Daniel Acosta-Soba , Francisco Guillén-González , J. Rafael Rodríguez-Galván

This paper introduces a stabilized finite element scheme for the Cahn--Hilliard cross-diffusion model, which is characterized by strongly coupled mobilities, nonlinear diffusion, and complex cross-diffusion terms. These features pose…

Numerical Analysis · Mathematics 2025-05-08 Boyi Wang , Naresh Kumar , Jinyun Yuan

This paper proposes a finite element scheme, based on the Scalar Auxiliary Variable (SAV) approach, for the Cahn-Hilliard equation--a model that possesses significant physical relevance and a rich mathematical structure. A convergence…

Numerical Analysis · Mathematics 2026-02-26 Na Li , Yongchao Zhao

We introduce a new phase field model for tumour growth where viscoelastic effects are taken into account. The model is derived from basic thermodynamical principles and consists of a convected Cahn--Hilliard equation with source terms for…

Numerical Analysis · Mathematics 2024-06-21 Harald Garcke , Balázs Kovács , Dennis Trautwein

In this paper we present PDE and finite element analyses for a system of partial differential equations (PDEs) consisting of the Darcy equation and the Cahn-Hilliard equation, which arises as a diffuse interface model for the two phase…

Numerical Analysis · Mathematics 2013-04-26 Xiaobing Feng , Steven Wise

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

Analysis of PDEs · Mathematics 2025-10-09 Giulia Cavalleri

The Cahn-Hilliard equation is one of the most common models to describe phase separation processes in mixtures of two materials. For a better description of short-range interactions between the material and the boundary, various dynamic…

Numerical Analysis · Mathematics 2023-01-23 Stefan Metzger

In this work, we propose a structure-preserving discretisation for the recently studied Cahn-Hilliard-Biot system using conforming finite elements in space and problem-adapted explicit-implicit Euler time integration. We prove that the…

Numerical Analysis · Mathematics 2024-07-18 Aaron Brunk , Marvin Fritz

In this paper, we tackle the problem of reconstructing earlier tumour configurations starting from a single spatial measurement at a later time. We describe the tumour evolution through a diffuse interface model coupling a…

Analysis of PDEs · Mathematics 2024-09-25 Abramo Agosti , Elena Beretta , Cecilia Cavaterra , Matteo Fornoni , Elisabetta Rocca

We propose a new type of diffuse interface model describing the evolution of a tumor mass under the effects of a chemical substance (e.g., a nutrient or a drug). The process is described by utilizing the variables $\varphi$, an order…

Analysis of PDEs · Mathematics 2022-02-23 Elisabetta Rocca , Giulio Schimperna , Andrea Signori

We propose a new numerical method to solve the Cahn-Hilliard equation coupled with non-linear wetting boundary conditions. We show that the method is mass-conservative and that the discrete solution satisfies a discrete energy law similar…

Numerical Analysis · Mathematics 2019-10-21 B. Aymard , U. Vaes , M. Pradas , S. Kalliadasis

We consider a diffuse interface model for tumour growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the…

Analysis of PDEs · Mathematics 2016-05-26 Harald Garcke , Kei Fong Lam

The scalar auxiliary variable (SAV) approach of Shen et al. (2018), which presents a novel way to discretize a large class of gradient flows, has been extended and improved by many authors for general dissipative systems. In this work we…

Numerical Analysis · Mathematics 2025-01-16 Kei Fong Lam , Ru Wang

A proof of optimal-order error estimates is given for the full discretization of the bulk--surface Cahn--Hilliard system with dynamic boundary conditions in a smooth domain. The numerical method combines a linear bulk--surface finite…

Numerical Analysis · Mathematics 2025-02-07 Nils Bullerjahn

In this paper, we investigate numerically a diffuse interface model for the Navier-Stokes equation with fluid-fluid interface when the fluids have different densities \cite{Lowengrub1998}. Under minor reformulation of the system, we show…

Mathematical Physics · Physics 2015-06-18 Zhenlin Guo , Ping Lin , John S. Lowengrub

An adaptive implicit-explicit (IMEX) BDF2 scheme is investigated on generalized SAV approach for the Cahn-Hilliard equation by combining with Fourier spectral method in space. It is proved that the modified energy dissipation law is…

Numerical Analysis · Mathematics 2022-11-04 Yifan Wei , Jiwei Zhang , Chengchao Zhao , Yanmin Zhao

In this work, we design and analyze semi/fully-discrete virtual element approximations for the time-dependent Navier--Stokes-Cahn--Hilliard equations, modeling the dynamics of two-phase incompressible fluid flows with diffuse interfaces. A…

Numerical Analysis · Mathematics 2026-01-27 Alberth Silgado , Giuseppe Vacca

We analyze a fully discrete finite element numerical scheme for the Cahn-Hilliard-Stokes-Darcy system that models two-phase flows in coupled free flow and porous media. To avoid a well-known difficulty associated with the coupling between…

Numerical Analysis · Mathematics 2021-06-08 Wenbin Chen , Daozhi Han , Cheng Wang , Shufen Wang , Xiaoming Wang , Yichao Zhang

For a Keller-Segel model for chemotaxis in two spatial dimensions we consider a modification of a positivity preserving fully discrete scheme using a local extremum diminishing flux limiter. We discretize space using piecewise linear finite…

Numerical Analysis · Mathematics 2026-02-20 Panagiotis Chatzipantelidis , Christos Pervolianakis
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