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Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

A pivotal advancement in the progress of large language models (LLMs) is the emergence of the Mixture-of-Experts (MoE) LLMs. Compared to traditional LLMs, MoE LLMs can achieve higher performance with fewer parameters, but it is still hard…

Computation and Language · Computer Science 2024-05-31 Xudong Lu , Qi Liu , Yuhui Xu , Aojun Zhou , Siyuan Huang , Bo Zhang , Junchi Yan , Hongsheng Li

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

The transformative impact of large language models (LLMs) like LLaMA and GPT on natural language processing is countered by their prohibitive computational demands. Pruning has emerged as a pivotal compression strategy, introducing sparsity…

Computation and Language · Computer Science 2024-11-04 Guangji Bai , Yijiang Li , Chen Ling , Kibaek Kim , Liang Zhao

Large language models (LLMs) have achieved remarkable success across various tasks but face deployment challenges due to their massive computational demands. While post-training pruning methods like SparseGPT and Wanda can effectively…

Artificial Intelligence · Computer Science 2026-04-21 Qiao Xiao , Alan Ansell , Boqian Wu , Lu Yin , Mykola Pechenizkiy , Shiwei Liu , Decebal Constantin Mocanu

Sparse Mixture of Experts (MoE) large language models (LLMs) are gradually becoming the mainstream approach for ultra-large-scale models. Existing optimization efforts for MoE models have focused primarily on coarse-grained MoE…

Computation and Language · Computer Science 2025-05-07 Haoqi Yang , Luohe Shi , Qiwei Li , Zuchao Li , Ping Wang , Bo Du , Mengjia Shen , Hai Zhao

Fine-tuning LLMs is both computationally and memory-intensive. While parameter-efficient fine-tuning methods, such as QLoRA and DoRA, reduce the number of trainable parameters and lower memory usage, they do not decrease computational cost.…

With the remarkable success of large language models (LLMs) in natural language understanding and generation, multimodal large language models (MLLMs) have rapidly advanced in their ability to process data across multiple modalities. While…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Jingrui Zhang , Feng Liang , Yong Zhang , Wei Wang , Runhao Zeng , Xiping Hu

Due to the cost-prohibitive nature of training Large Language Models (LLMs), fine-tuning has emerged as an attractive alternative for specializing LLMs for specific tasks using limited compute resources in a cost-effective manner. In this…

Computation and Language · Computer Science 2024-08-15 Yuchen Xia , Jiho Kim , Yuhan Chen , Haojie Ye , Souvik Kundu , Cong Hao , Nishil Talati

Communication-efficient distributed training algorithms have received considerable interest recently due to their benefits for training Large Language Models (LLMs) in bandwidth-constrained settings, such as across datacenters and over the…

Machine Learning · Computer Science 2025-11-07 Amir Sarfi , Benjamin Thérien , Joel Lidin , Eugene Belilovsky

Large language models (LLMs) have demonstrated proficiency across various natural language processing (NLP) tasks but often require additional training, such as continual pre-training and supervised fine-tuning. However, the costs…

Computation and Language · Computer Science 2024-06-07 Da Ma , Lu Chen , Pengyu Wang , Hongshen Xu , Hanqi Li , Liangtai Sun , Su Zhu , Shuai Fan , Kai Yu

Existing low-rank adaptation (LoRA) methods face challenges on sparse large language models (LLMs) due to the inability to maintain sparsity. Recent works introduced methods that maintain sparsity by augmenting LoRA techniques with…

Computation and Language · Computer Science 2025-01-16 Yuxuan Hu , Jing Zhang , Xiaodong Chen , Zhe Zhao , Cuiping Li , Hong Chen

The entry of large language models (LLMs) into research and commercial spaces has led to a trend of ever-larger models, with initial promises of generalisability, followed by a widespread desire to downsize and create specialised models…

Computation and Language · Computer Science 2024-02-19 Niall Taylor , Upamanyu Ghose , Omid Rohanian , Mohammadmahdi Nouriborji , Andrey Kormilitzin , David Clifton , Alejo Nevado-Holgado

The recent surge in Large Language Models (LLMs) has garnered significant attention across numerous fields. Fine-tuning is often required to fit general LLMs for a specific domain, like the web-based healthcare system. However, two problems…

Computation and Language · Computer Science 2024-06-03 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Derong Xu , Feng Tian , Yefeng Zheng

Adapting medical Large Language Models to local languages can reduce barriers to accessing healthcare services, but data scarcity remains a significant challenge, particularly for low-resource languages. To address this, we first construct…

Computation and Language · Computer Science 2025-02-11 Guorui Zheng , Xidong Wang , Juhao Liang , Nuo Chen , Yuping Zheng , Benyou Wang

Vision-Language Models (VLMs) integrate information from multiple modalities and have shown remarkable success across various tasks. However, deploying large-scale VLMs in resource-constrained scenarios is challenging. Pruning followed by…

Machine Learning · Computer Science 2024-06-26 Shwai He , Ang Li , Tianlong Chen

Recently, inspired by the concept of sparsity, Mixture-of-Experts (MoE) models have gained increasing popularity for scaling model size while keeping the number of activated parameters constant. In this study, we thoroughly investigate the…

Computation and Language · Computer Science 2024-11-26 Xiaoye Qu , Daize Dong , Xuyang Hu , Tong Zhu , Weigao Sun , Yu Cheng

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

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