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Histopathological diagnoses of tumors in tissue biopsy after Hematoxylin and Eosin (H&E) staining is the gold standard for oncology care. H&E staining is slow and uses dyes, reagents and precious tissue samples that cannot be reused.…

Digital scans of analogue photographic film typically contain artefacts such as dust and scratches. Automated removal of these is an important part of preservation and dissemination of photographs of historical and cultural importance.…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Daniela Ivanova , John Williamson , Paul Henderson

Segmentation from renal pathological images is a key step in automatic analyzing the renal histological characteristics. However, the performance of models varies significantly in different types of stained datasets due to the appearance…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Ke Mei , Chuang Zhu , Lei Jiang , Jun Liu , Yuanyuan Qiao

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Joint analysis of multiple biomarker images and tissue morphology is important for disease diagnosis, treatment planning and drug development. It requires cross-staining comparison among Whole Slide Images (WSIs) of immuno-histochemical and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Abubakr Shafique , Morteza Babaie , Mahjabin Sajadi , Adrian Batten , Soma Skdar , H. R. Tizhoosh

Despite over two decades of progress, imbalanced data is still considered a significant challenge for contemporary machine learning models. Modern advances in deep learning have magnified the importance of the imbalanced data problem. The…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Damien Dablain , Bartosz Krawczyk , Nitesh V. Chawla

Story visualization aims to generate a sequence of images to narrate each sentence in a multi-sentence story, where the images should be realistic and keep global consistency across dynamic scenes and characters. Current works face the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Bowen Li , Thomas Lukasiewicz

Generative AI presents transformative potential across various domains, from creative arts to scientific visualization. However, the utility of AI-generated imagery is often compromised by visual flaws, including anatomical inaccuracies,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhenyu Yu , Chee Seng Chan

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

Tumor spatial heterogeneity analysis requires precise correlation between Hematoxylin and Eosin H&E morphology and immunohistochemical (IHC) biomarker expression, yet current methods suffer from spatial misalignment in consecutive sections,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yizhe Yuan , Bingsen Xue , Bangzheng Pu , Chengxiang Wang , Cheng Jin

Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Jingsong Liu , Xiaofeng Deng , Han Li , Azar Kazemi , Christian Grashei , Gesa Wilkens , Xin You , Tanja Groll , Nassir Navab , Carolin Mogler , Peter J. Schüffler

Online sampling-supported visual analytics is increasingly important, as it allows users to explore large datasets with acceptable approximate answers at interactive rates. However, existing online spatiotemporal sampling techniques are…

This paper introduces a Virtual Immunohistochemistry Multiplex staining (VIMs) model designed to generate multiple immunohistochemistry (IHC) stains from a single hematoxylin and eosin (H&E) stained tissue section. IHC stains are crucial in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Shikha Dubey , Yosep Chong , Beatrice Knudsen , Shireen Y. Elhabian

Precise pose estimation of optical microrobots is essential for enabling high-precision object tracking and autonomous biological studies. However, current methods rely heavily on large, high-quality microscope image datasets, which are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zongcai Tan , Lan Wei , Dandan Zhang

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Hard coatings play a critical role in industry, with ceramic materials offering outstanding hardness and thermal stability for applications that demand superior mechanical performance. However, deploying artificial intelligence (AI) for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Binwei Chen , Huachao Leng , Chi Yeung Mang , Tsz Wai Cheung , Yanhua Chen , Wai Keung Anthony Loh , Chi Ho Wong , Chak Yin Tang

Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Xianxu Hou , Jingxin Liu , Bolei Xu , Bozhi Liu , Xin Chen , Mohammad Ilyas , Ian Ellis , Jon Garibaldi , Guoping Qiu

Texture synthesis is a fundamental task in computer vision, whose goal is to generate visually realistic and structurally coherent textures for a wide range of applications, from graphics to scientific simulations. While traditional methods…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Elahe Salari , Zohreh Azimifar

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

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