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Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

In this work, we introduce a fast and accurate method for unsupervised 3D medical image registration. This work is built on top of a recent algorithm SAM, which is capable of computing dense anatomical/semantic correspondences between two…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Fengze Liu , Ke Yan , Adam Harrison , Dazhou Guo , Le Lu , Alan Yuille , Lingyun Huang , Guotong Xie , Jing Xiao , Xianghua Ye , Dakai Jin

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Image registration is a fundamental medical image analysis task. Ideally, registration should focus on aligning semantically corresponding voxels, i.e., the same anatomical locations. However, existing methods often optimize similarity…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Lin Tian , Zi Li , Fengze Liu , Xiaoyu Bai , Jia Ge , Le Lu , Marc Niethammer , Xianghua Ye , Ke Yan , Daikai Jin

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu

Medical images like CT and MRI provide detailed information about the internal structure of the body, and identifying key anatomical structures from these images plays a crucial role in clinical workflows. Current methods treat it as a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xiaoyu Bai , Yong Xia

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Image registration is an essential step in many medical image analysis tasks. Traditional methods for image registration are primarily optimization-driven, finding the optimal deformations that maximize the similarity between two images.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Shanlin Sun , Kun Han , Chenyu You , Hao Tang , Deying Kong , Junayed Naushad , Xiangyi Yan , Haoyu Ma , Pooya Khosravi , James S. Duncan , Xiaohui Xie

The Segment Anything Model (SAM) is the first foundation model for general image segmentation. It has achieved impressive results on various natural image segmentation tasks. However, medical image segmentation (MIS) is more challenging…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Yuhao Huang , Xin Yang , Lian Liu , Han Zhou , Ao Chang , Xinrui Zhou , Rusi Chen , Junxuan Yu , Jiongquan Chen , Chaoyu Chen , Sijing Liu , Haozhe Chi , Xindi Hu , Kejuan Yue , Lei Li , Vicente Grau , Deng-Ping Fan , Fajin Dong , Dong Ni

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have shown strong performance in various vision tasks, particularly image segmentation, due to their impressive zero-shot segmentation capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Pengfei Gu , Haoteng Tang , Islam A. Ebeid , Jose A. Nunez , Fabian Vazquez , Diego Adame , Marcus Zhan , Huimin Li , Bin Fu , Danny Z. Chen

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Shreyank N Gowda , David A. Clifton

Image segmentation remains a pivotal component in medical image analysis, aiding in the extraction of critical information for precise diagnostic practices. With the advent of deep learning, automated image segmentation methods have risen…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Nhat-Tan Bui , Dinh-Hieu Hoang , Minh-Triet Tran , Gianfranco Doretto , Donald Adjeroh , Brijesh Patel , Arabinda Choudhary , Ngan Le

Summary: SAMRI is an MRI-specialized adaptation of the Segment Anything Model achieving superior whole-body MRI segmentation, particularly for small and clinically critical structures, through box and point prompts for rapid annotation.…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhao Wang , Wei Dai , Thuy Thanh Dao , Steffen Bollmann , Hongfu Sun , Craig Engstrom , Shekhar S. Chandra

One-shot medical image segmentation (MIS) is crucial for medical analysis due to the burden of medical experts on manual annotation. The recent emergence of the segment anything model (SAM) has demonstrated remarkable adaptation in MIS but…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Jia Wang , Yunan Mei , Jiarui Liu , Xin Fan

The Segment Anything Model (SAM), a foundation model for general image segmentation, has demonstrated impressive zero-shot performance across numerous natural image segmentation tasks. However, SAM's performance significantly declines when…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Cheng Chen , Juzheng Miao , Dufan Wu , Zhiling Yan , Sekeun Kim , Jiang Hu , Aoxiao Zhong , Zhengliang Liu , Lichao Sun , Xiang Li , Tianming Liu , Pheng-Ann Heng , Quanzheng Li

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou
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