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Related papers: SHREC 2025: Protein surface shape retrieval includ…

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MIDOG 2025 Track 1 requires mitosis detection in whole-slideimages (WSIs) containing non-tumor, inflamed, and necrotic re-gions. Due to the complicated and heterogeneous context, aswell as possible artifacts, there are often false positives…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Jie Xiao , Mengye Lyu , Shaojun Liu

The rapid growth in the number of experimental and predicted protein structures and more complicated protein structures challenge users in computational biology for utilizing the structural information and protein surface property…

Quantitative Methods · Quantitative Biology 2023-08-08 Junkang Wei , Jin Xiao , Siyuan Chen , Licheng Zong , Xin Gao , Yu Li

A coarse-grained computational procedure based on the Finite Element Method is proposed to calculate the normal modes and mechanical response of proteins and their supramolecular assemblies. Motivated by the elastic network model, proteins…

Biomolecules · Quantitative Biology 2007-05-23 Mark Bathe

The increasing number of protein-based metamaterials demands reliable and efficient theoretical and computational methods to study the physicochemical properties they may display. In this regard, we develop a simulation strategy based on…

Soft Condensed Matter · Physics 2020-06-23 J. A. Campos Gonzalez Angulo , G. Wiesehan , R. F. Ribeiro , J. Yuen-Zhou

This paper presents a iterative optimization method, explicit shape regression, for face pose detection and localization. The regression function is learnt to find out the entire facial shape and minimize the alignment errors. A cascaded…

Computer Vision and Pattern Recognition · Computer Science 2017-09-12 Wenye He

Simulating charged many-body systems has been a computational demanding task due to the long-range nature of electrostatic interaction. For the multi-scale model of electrolytes which combines the strengths of atomistic/continuum…

Computational Physics · Physics 2022-07-22 Jing Fu , Zecheng Gan

We participated in three of the protein-protein interaction subtasks of the Second BioCreative Challenge: classification of abstracts relevant for protein-protein interaction (IAS), discovery of protein pairs (IPS) and text passages…

Determining the 3D structures of proteins is essential in understanding their behavior in the cellular environment. Computational methods of predicting protein structures have advanced, but assessing prediction accuracy remains a challenge.…

Biomolecules · Quantitative Biology 2024-07-29 Musa Azeem , Homayoun Valafar

A generalized computational method for folding proteins with a fully transferable potential and geometrically realistic all-atom model is presented and tested on seven different helix bundle proteins. The protocol, which includes…

Biomolecules · Quantitative Biology 2009-11-11 Isaac A. Hubner , Eric J. Deeds , Eugene I. Shakhnovich

The advent of highly accurate protein structure prediction methods has fueled an exponential expansion of the protein structure database. Consequently, there is a rising demand for rapid and precise structural homolog search. Traditional…

Biomolecules · Quantitative Biology 2023-12-01 Yuan Liu , Hong-Bin Shen

Identifying unique parameters for mathematical models describing biological data can be challenging and often impossible. Parameter identifiability for partial differential equations models in cell biology is especially difficult given that…

Quantitative Methods · Quantitative Biology 2024-03-05 Maria-Veronica Ciocanel , Lee Ding , Lucas Mastromatteo , Sarah Reichheld , Sarah Cabral , Kimberly Mowry , Bjorn Sandstede

We present a model, based on symmetry and geometry, for proteins. Using elementary ideas from mathematics and physics, we derive the geometries of discrete helices and sheets. We postulate a compatible solvent-mediated emergent pairwise…

Soft Condensed Matter · Physics 2023-06-21 Jayanth R. Banavar , Achille Giacometti , Trinh X. Hoang , Amos Maritan , Tatjana Škrbić

We report a 3D structure-based method of predicting protein-protein interaction partners. It involves screening for pairs of tetrahedra representing interacting amino acids at the interface of the protein-protein complex, with one…

Biomolecules · Quantitative Biology 2015-05-06 Vicente M. Reyes

This paper presents a comprehensive study and benchmark on Efficient Perceptual Super-Resolution (EPSR). While significant progress has been made in efficient PSNR-oriented super resolution, approaches focusing on perceptual quality metrics…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Bruno Longarela , Marcos V. Conde , Alvaro Garcia , Radu Timofte

In this paper we present a new methodology for edge detection in digital images. The first originality of the proposed method is to consider image content as a parametric surface. Then, an original parametric local model of this surface…

Image and Video Processing · Electrical Eng. & Systems 2019-04-24 Rémi Cogranne , Rémi Slysz , Laurence Moreau , Houman Borouchaki

We introduce SANDesc, a Streamlined Attention-Based Network for Descriptor extraction that aims to improve on existing architectures for keypoint description. Our descriptor network learns to compute descriptors that improve matching…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Mattia D'Urso , Emanuele Santellani , Christian Sormann , Mattia Rossi , Andreas Kuhn , Friedrich Fraundorfer

Protein structures represent the key to deciphering biological functions. The more detailed form of similarity among these proteins is sometimes overlooked by the conventional structural comparison methods. In contrast, further advanced…

Machine Learning · Computer Science 2026-01-21 Poorya Khajouie , Titli Sarkar , Krishna Rauniyar , Li Chen , Wu Xu , Vijay Raghavan

Scanning transmission electron microscopy (STEM) has been extensively used for imaging complex materials down to atomic resolution. The most commonly employed STEM modality, annular dark-field imaging, produces easily-interpretable…

Proteins are inherently multiscale physical systems whose functional properties emerge from coordinated structural organization across multiple spatial resolutions, ranging from atomic interactions to global fold topology. However, existing…

Machine Learning · Computer Science 2026-05-13 Viet Thanh Duy Nguyen , John K. Johnstone , Truong-Son Hy

Learned representations of scientific documents can serve as valuable input features for downstream tasks without further fine-tuning. However, existing benchmarks for evaluating these representations fail to capture the diversity of…

Computation and Language · Computer Science 2023-11-14 Amanpreet Singh , Mike D'Arcy , Arman Cohan , Doug Downey , Sergey Feldman