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Detecting novel anomalies in medical imaging is challenging due to the limited availability of labeled data for rare abnormalities, which often display high variability and subtlety. This challenge is further compounded when small abnormal…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Jingkun Chen , Guang Yang , Xiao Zhang , Jingchao Peng , Tianlu Zhang , Jianguo Zhang , Jungong Han , Vicente Grau

Anomaly detection and localization in medical images is a challenging task, especially when the anomaly exhibits a change of existing structures, e.g., brain atrophy or changes in the pleural space due to pleural effusions. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Unsupervised anomaly detection aims to identify anomalies without pixel-level annotations. Synthetic anomaly-based methods exhibit a unique capacity to introduce controllable irregularities with known masks, enabling explicit supervision…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Qinyi Cao , Jianan Fan , Weidong Cai

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Changhee Han , Leonardo Rundo , Kohei Murao , Tomoyuki Noguchi , Yuki Shimahara , Zoltan Adam Milacski , Saori Koshino , Evis Sala , Hideki Nakayama , Shinichi Satoh

Chest radiography is climacteric in identifying different pulmonary diseases, yet radiologist workload and inefficiency can lead to misdiagnoses. Automatic, accurate, and efficient segmentation of lung from X-ray images of chest is…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Sharmin Akter

Fine-grained anomaly detection has recently been dominated by segmentation based approaches. These approaches first classify each element of the sample (e.g., image patch) as normal or anomalous and then classify the entire sample as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Niv Cohen , Issar Tzachor , Yedid Hoshen

Zero-shot anomaly classification and segmentation (AC/AS) aim to detect anomalous samples and regions without any training data, a capability increasingly crucial in industrial inspection and medical imaging. This dissertation aims to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Tai Le-Gia

The essence of unsupervised anomaly detection is to learn the compact distribution of normal samples and detect outliers as anomalies in testing. Meanwhile, the anomalies in real-world are usually subtle and fine-grained in a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Ye Zheng , Xiang Wang , Rui Deng , Tianpeng Bao , Rui Zhao , Liwei Wu

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Segmenting anatomical structures in medical images has been successfully addressed with deep learning methods for a range of applications. However, this success is heavily dependent on the quality of the image that is being segmented. A…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Ilkay Oksuz , James R. Clough , Bram Ruijsink , Esther Puyol Anton , Aurelien Bustin , Gastao Cruz , Claudia Prieto , Andrew P. King , Julia A. Schnabel

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Over the past years, pseudo-healthy reconstruction for unsupervised anomaly detection has gained in popularity. This approach has the great advantage of not requiring tedious pixel-wise data annotation and offers possibility to generalize…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Ravi Hassanaly , Camille Brianceau , Maëlys Solal , Olivier Colliot , Ninon Burgos

Anomaly detection (AD) is a fundamental research problem in machine learning and computer vision, with practical applications in industrial inspection, video surveillance, and medical diagnosis. In medical imaging, AD is especially vital…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Jinan Bao , Hanshi Sun , Hanqiu Deng , Yinsheng He , Zhaoxiang Zhang , Xingyu Li

This paper presents a fast and principled approach for solving the visual anomaly detection and segmentation problem. In this setup, we have access to only anomaly-free training data and want to detect and identify anomalies of an arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Ibrahima Ndiour , Nilesh Ahuja , Utku Genc , Omesh Tickoo

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

One pivot challenge for image anomaly (AD) detection is to learn discriminative information only from normal class training images. Most image reconstruction based AD methods rely on the discriminative capability of reconstruction error.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Dongyun Lin , Yiqun Li , Shudong Xie , Tin Lay Nwe , Sheng Dong

Deep learning models in medical imaging often encounter challenges when adapting to new clinical settings unseen during training. Test-time adaptation offers a promising approach to optimize models for these unseen domains, yet its…

Machine Learning · Computer Science 2024-10-28 Sameer Ambekar , Julia A. Schnabel , Cosmin I. Bercea

We present a system for anomaly detection in histopathological images. In histology, normal samples are usually abundant, whereas anomalous (pathological) cases are scarce or not available. Under such settings, one-class classifiers trained…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Igor Zingman , Birgit Stierstorfer , Charlotte Lempp , Fabian Heinemann

Anomaly detection (AD) in images, identifying significant deviations from normality, is a critical issue in computer vision. This paper introduces a novel approach to dimensionality reduction for AD using pre-trained convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Tetiana Gula , João P C Bertoldo