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In clinical data sets we often find static information (e.g. patient gender, blood type, etc.) combined with sequences of data that are recorded during multiple hospital visits (e.g. medications prescribed, tests performed, etc.). Recurrent…

Machine Learning · Computer Science 2016-11-18 Cristóbal Esteban , Oliver Staeck , Yinchong Yang , Volker Tresp

Lymph node (LN) assessment is a critical, indispensable yet very challenging task in the routine clinical workflow of radiology and oncology. Accurate LN analysis is essential for cancer diagnosis, staging, and treatment planning. Finding…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Yirui Wang , Qinji Yu , Ke Yan , Haoshen Li , Dazhou Guo , Li Zhang , Le Lu , Na Shen , Qifeng Wang , Xiaowei Ding , Xianghua Ye , Dakai Jin

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Discriminative features play an important role in image and object classification and also in other fields of research such as semi-supervised learning, fine-grained classification, out of distribution detection. Inspired by Linear…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Mai Lan Ha , Gianni Franchi , Emanuel Aldea , Volker Blanz

As COVID-19 transitions into an endemic disease that remains constantly present in the population at a stable level, monitoring its prevalence without invasive measures becomes increasingly important. In this paper, we present a deep neural…

Quantitative Methods · Quantitative Biology 2025-12-02 Yifei Chen , Eric Liang

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

In routine care, individuals identified a priori as high-risk are usually tested for conditions more frequently. Protected attributes, such as sex or ethnicity may also determine testing frequency. Such heterogeneous detection rates across…

Applications · Statistics 2026-05-08 Jose Benitez-Aurioles , Ricardo Silva , Brian McMillan , Matthew Sperrin

We found that the real time reverse transcription-polymerase chain reaction (RT-PCR) detection of viral RNA from sputum or nasopharyngeal swab has a relatively low positive rate in the early stage to determine COVID-19 (named by the World…

Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring…

We introduce Neural Representation of Distribution (NeRD) technique, a module for convolutional neural networks (CNNs) that can estimate the feature distribution by optimizing an underlying function mapping image coordinates to the feature…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Hang Zhang , Rongguang Wang , Jinwei Zhang , Chao Li , Gufeng Yang , Pascal Spincemaille , Thanh Nguyen , Yi Wang

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Data cleaning consumes about 80% of the time spent on data analysis for clinical research projects. This is a much bigger problem in the era of big data and machine learning in the field of medicine where large volumes of data are being…

Medical Physics · Physics 2018-01-03 Timothy Rozario , Troy Long , Mingli Chen , Weiguo Lu , Steve Jiang

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

Machine Learning · Statistics 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

Computer-aided diagnosis (CAD) is becoming a prominent approach to assist clinicians spanning across multiple fields. These automated systems take advantage of various computer vision (CV) procedures, as well as artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Danilo Avola , Luigi Cinque , Alessio Fagioli , Sebastiano Filetti , Giorgio Grani , Emanuele Rodolà

Understanding the anatomy of renal pathology is crucial for advancing disease diagnostics, treatment evaluation, and clinical research. The complex kidney system comprises various components across multiple levels, including regions…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Ruining Deng , Quan Liu , Can Cui , Tianyuan Yao , Jialin Yue , Juming Xiong , Lining Yu , Yifei Wu , Mengmeng Yin , Yu Wang , Shilin Zhao , Yucheng Tang , Haichun Yang , Yuankai Huo

In response to the pressing challenge of kidney allocation, characterized by growing demands for organs, this research sets out to develop a data-driven solution to this problem, which also incorporates stakeholder values. The primary…

The pandemic of coronavirus disease 2019 (COVID-19) has lead to a global public health crisis spreading hundreds of countries. With the continuous growth of new infections, developing automated tools for COVID-19 identification with CT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Zhao Wang , Quande Liu , Qi Dou

Renal compartment segmentation on CT images targets on extracting the 3D structure of renal compartments from abdominal CTA images and is of great significance to the diagnosis and treatment for kidney diseases. However, due to the unclear…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Song Wang , Yuting He , Youyong Kong , Xiaomei Zhu , Shaobo Zhang , Pengfei Shao , Jean-Louis Dillenseger , Jean-Louis Coatrieux , Shuo Li , Guanyu Yang

An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival…

Machine Learning · Computer Science 2017-05-30 Margaux Luck , Tristan Sylvain , Héloïse Cardinal , Andrea Lodi , Yoshua Bengio