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Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

The advent of multimodal large language models (MLLMs) has sparked interest in their application to electrocardiogram (ECG) analysis. However, existing ECG-focused MLLMs primarily focus on report generation tasks, often limited to single…

Computation and Language · Computer Science 2025-11-13 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

ECG-Language Models (ELMs) extend recent progress in Multimodal Large Language Models (MLLMs) to automated ECG interpretation. However, most ELMs follow Vision-Language Model (VLM) designs and depend on pretrained ECG encoders, adding…

Large Language Models (LLMs) have demonstrated exceptional versatility across domains, including applications to electrocardiograms (ECGs). A growing body of work focuses on generating text from multi-channeled ECG signals and corresponding…

Computation and Language · Computer Science 2025-07-31 William Han , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Recent advances have increasingly applied large language models (LLMs) to electrocardiogram (ECG) interpretation, giving rise to Electrocardiogram-Language Models (ELMs). Conditioned on an ECG and a textual query, an ELM autoregressively…

Artificial Intelligence · Computer Science 2025-05-27 William Han , Chaojing Duan , Zhepeng Cen , Yihang Yao , Xiaoyu Song , Atharva Mhaskar , Dylan Leong , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Automated interpretation of electrocardiograms (ECG) has garnered significant attention with the advancements in machine learning methodologies. Despite the growing interest, most current studies focus solely on classification or regression…

Signal Processing · Electrical Eng. & Systems 2023-11-07 Jielin Qiu , Jiacheng Zhu , Shiqi Liu , William Han , Jingqi Zhang , Chaojing Duan , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

Recent advancements in Large Language Models (LLMs) have drawn increasing attention since the learned embeddings pretrained on large-scale datasets have shown powerful ability in various downstream applications. However, whether the learned…

Computation and Language · Computer Science 2023-02-07 Jielin Qiu , William Han , Jiacheng Zhu , Mengdi Xu , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

Electrocardiogram (ECG) monitoring is one of the most powerful technique of cardiovascular disease (CVD) early identification, and the introduction of intelligent wearable ECG devices has enabled daily monitoring. However, due to the need…

Signal Processing · Electrical Eng. & Systems 2024-03-08 Hongxiang Gao , Xingyao Wang , Zhenghua Chen , Min Wu , Jianqing Li , Chengyu Liu

Electrocardiography (ECG) serves as an indispensable diagnostic tool in clinical practice, yet existing multimodal large language models (MLLMs) remain unreliable for ECG interpretation, often producing plausible but clinically incorrect…

Computation and Language · Computer Science 2026-05-26 Jiarui Jin , Haoyu Wang , Xingliang Wu , Xiaocheng Fang , Xiang Lan , Zihan Wang , Deyun Zhang , Bo Liu , Yingying Zhang , Xian Wu , Hongyan Li , Shenda Hong

Multimodal large language models (MLLMs) are increasingly being applied in the medical field, particularly in medical imaging. However, developing MLLMs for ECG signals, which are crucial in clinical settings, has been a significant…

Computation and Language · Computer Science 2024-11-25 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

The success of Multimodal Large Language Models (MLLMs) in the medical auxiliary field shows great potential, allowing patients to engage in conversations using physiological signal data. However, general MLLMs perform poorly in cardiac…

Signal Processing · Electrical Eng. & Systems 2025-04-17 Yubao Zhao , Jiaju Kang , Tian Zhang , Puyu Han , Tong Chen

The emergence of deep learning has significantly enhanced the analysis of electrocardiograms (ECGs), a non-invasive method that is essential for assessing heart health. Despite the complexity of ECG interpretation, advanced deep learning…

Machine Learning · Computer Science 2023-06-05 Zibin Zhao

The growing convergence between Large Language Models (LLMs) and electroencephalography (EEG) research is enabling new directions in neural decoding, brain-computer interfaces (BCIs), and affective computing. This survey offers a systematic…

Signal Processing · Electrical Eng. & Systems 2025-06-11 Naseem Babu , Jimson Mathew , A. P. Vinod

Electrocardiogram (ECG) foundation models represent a paradigm shift from task-specific pipelines to generalizable architectures pre-trained on large-scale unlabeled waveform data. This survey presents a unified and deployment-aware review…

Signal Processing · Electrical Eng. & Systems 2026-04-06 Mudassir Hasan Khan , Ahmad Nayfeh , Mudassir Masood , Ali Ahmad Al-Shaikhi , Muhammad Mahboob Ur Rahman , Tareq Y. Al-Naffouri

Electrocardiography (ECG) plays a central role in cardiovascular diagnostics, yet existing automated approaches often struggle to generalize across clinical tasks and offer limited support for open-ended reasoning. We present HeartLLM, a…

Artificial Intelligence · Computer Science 2026-01-27 Jinning Yang , Wenjie Sun , Wen Shi

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

Conventional augmentative and alternative communication (AAC) systems and language-learning platforms often fail to adapt in real time to the user's cognitive and linguistic needs, especially in neurological conditions such as post-stroke…

Human-Computer Interaction · Computer Science 2025-08-01 Ismail Hossain , Mridul Banik

Electroencephalography provides a non-invasive window into brain activity, offering valuable insights for neurological research, brain-computer interfaces, and clinical diagnostics. However, the development of robust machine learning models…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Chi-Sheng Chen , Ying-Jung Chen , Aidan Hung-Wen Tsai

Interpreting electrocardiograms (ECGs) and generating comprehensive reports remain challenging tasks in cardiology, often requiring specialized expertise and significant time investment. To address these critical issues, we propose…

Machine Learning · Computer Science 2024-09-16 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed
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