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Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Viktoria Ehm , Anke Meyer-Baese , Jan C. Peeken , Daniel Rueckert , Benedikt Wiestler

Unsupervised anomaly detection (AD) in medical images aims to identify abnormal regions without relying on pixel-level annotations, which is crucial for scalable and label-efficient diagnostic systems. In this paper, we propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Jiayu Huo , Jingyuan Hong , Liyun Chen

Adnexal mass evaluation via ultrasound is a challenging clinical task, often hindered by subjective interpretation and significant inter-observer variability. While automated segmentation is a foundational step for quantitative risk…

Medical image segmentation is crucial for clinical decision-making, but the scarcity of annotated data presents significant challenges. Few-shot segmentation (FSS) methods show promise but often require training on the target domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Lin Zhao , Xiao Chen , Eric Z. Chen , Yikang Liu , Terrence Chen , Shanhui Sun

Current anomaly detection methods excel with benchmark industrial data but struggle with natural images and medical data due to varying definitions of 'normal' and 'abnormal.' This makes accurate identification of deviations in these fields…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Zeduo Zhang , Yalda Mohsenzadeh

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

Accurate left atrium (LA) segmentation from pre-operative scans is crucial for diagnosing atrial fibrillation, treatment planning, and supporting surgical interventions. While deep learning models are key in medical image segmentation, they…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Bipasha Kundu , Bidur Khanal , Richard Simon , Cristian A. Linte

MRI and CT are essential clinical cross-sectional imaging techniques for diagnosing complex conditions. However, large 3D datasets with annotations for deep learning are scarce. While methods like DINOv2 are encouraging for 2D image…

Image and Video Processing · Electrical Eng. & Systems 2025-07-10 Gustav Müller-Franzes , Firas Khader , Robert Siepmann , Tianyu Han , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

In this work, we leverage informative embeddings from foundational models for unsupervised anomaly detection in medical imaging. For small datasets, a memory-bank of normative features can directly be used for anomaly detection which has…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Nico Schulthess , Ender Konukoglu

Zero-Shot Anomaly Detection (ZSAD) seeks to identify anomalies from arbitrary novel categories, offering a scalable and annotation-efficient solution. Traditionally, most ZSAD works have been based on the CLIP model, which performs anomaly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Jingyi Yuan , Jianxiong Ye , Wenkang Chen , Chenqiang Gao

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

The integration of deep learning systems into healthcare has been hindered by the resource-intensive process of data annotation and the inability of these systems to generalize to different data distributions. Foundation models, which are…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Mohammed Baharoon , Waseem Qureshi , Jiahong Ouyang , Yanwu Xu , Abdulrhman Aljouie , Wei Peng

Timely and accurate diagnosis of appendicitis is critical in clinical settings to prevent serious complications. While CT imaging remains the standard diagnostic tool, the growing number of cases can overwhelm radiologists, potentially…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Chia-Wen Huang , Haw Hwai , Chien-Chang Lee , Pei-Yuan Wu

DINO models provide rich patch-level representations that have recently enabled strong performance in unsupervised anomaly detection (UAD). Most existing methods extract patch embeddings from ``normal'' images and model them independently,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Ertunc Erdil , Nico Schulthess , Guney Tombak , Ender Konukoglu

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Deep neural networks (DNNs) have been widely applied in medical image classification and achieve remarkable classification performance. These achievements heavily depend on large-scale accurately annotated training data. However, label…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Hongyang Jiang , Mengdi Gao , Yan Hu , Qiushi Ren , Zhaoheng Xie , Jiang Liu

The data-intensive nature of supervised classification drives the interest of the researchers towards unsupervised approaches, especially for problems such as medical image segmentation, where labeled data is scarce. Building on the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar
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