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Recent advancements in AI agents have demonstrated their growing potential to drive and support scientific discovery. In this work, we introduce MLR-Bench, a comprehensive benchmark for evaluating AI agents on open-ended machine learning…

Machine Learning · Computer Science 2025-10-23 Hui Chen , Miao Xiong , Yujie Lu , Wei Han , Ailin Deng , Yufei He , Jiaying Wu , Yibo Li , Yue Liu , Bryan Hooi

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

Academic writing is an indispensable yet laborious part of the research enterprise. This Perspective maps out principles and methods for using generative artificial intelligence (AI), specifically large language models (LLMs), to elevate…

Computers and Society · Computer Science 2026-04-07 Zhicheng Lin

In the age of large language models (LLMs), autonomous agents have emerged as a powerful paradigm for achieving general intelligence. These agents dynamically leverage tools, memory, and reasoning capabilities to accomplish user-defined…

Artificial Intelligence · Computer Science 2025-08-05 Chaojia Yu , Zihan Cheng , Hanwen Cui , Yishuo Gao , Zexu Luo , Yijin Wang , Hangbin Zheng , Yong Zhao

Large-language-model (LLM)-based AI agents have recently showcased impressive versatility by employing dynamic reasoning, an adaptive, multi-step process that coordinates with external tools. This shift from static, single-turn inference to…

Machine Learning · Computer Science 2026-01-08 Jiin Kim , Byeongjun Shin , Jinha Chung , Minsoo Rhu

The rapid advancement of scientific progress requires innovative tools that can accelerate knowledge discovery. Although recent AI methods, particularly large language models (LLMs), have shown promise in tasks such as hypothesis generation…

Artificial Intelligence · Computer Science 2025-05-28 Haoyang Su , Renqi Chen , Shixiang Tang , Zhenfei Yin , Xinzhe Zheng , Jinzhe Li , Biqing Qi , Qi Wu , Hui Li , Wanli Ouyang , Philip Torr , Bowen Zhou , Nanqing Dong

Agentic workflows are composed of sequences of interdependent Large Language Model (LLM) calls, and they have become a dominant workload in modern AI systems. These workflows exhibit extensive redundancy from overlapping prompts and…

Multiagent Systems · Computer Science 2026-03-18 Noppanat Wadlom , Junyi Shen , Yao Lu

For a long time, humanity has pursued artificial intelligence (AI) equivalent to or surpassing the human level, with AI agents considered a promising vehicle for this pursuit. AI agents are artificial entities that sense their environment,…

While Large Language Models (LLMs) offer a solution to the scale-versus-depth dilemma in qualitative analysis, the paradigm of maximizing automation is fundamentally at odds with the interpretive nature of qualitative inquiry. We argue that…

Human-Computer Interaction · Computer Science 2026-05-28 Feng Zhou , Jacqueline Meijer-Irons , Ambar Murillo

Artificial intelligence (AI) is reshaping scientific discovery, evolving from specialized computational tools into autonomous research partners. We position Agentic Science as a pivotal stage within the broader AI for Science paradigm,…

Modern scientific discovery increasingly requires coordinating distributed facilities and heterogeneous resources, forcing researchers to act as manual workflow coordinators rather than scientists. Advances in AI leading to AI agents show…

Artificial Intelligence · Computer Science 2025-09-15 Woong Shin , Renan Souza , Daniel Rosendo , Frédéric Suter , Feiyi Wang , Prasanna Balaprakash , Rafael Ferreira da Silva

Large language models (LLMs), have shown strong potential in scientific discovery, yet existing methods still face substantial challenges in the design of research workflows and multi-role collaboration mechanisms. To mitigate these issues,…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyu Xiong , Yuqi Ren , Deyi Xiong

Peer review remains the central quality-control mechanism of science, yet its ability to fulfill this role is increasingly strained. Empirical studies document serious shortcomings: long publication delays, escalating reviewer burden…

Scientific innovation relies on detailed workflows, which include critical steps such as analyzing literature, generating ideas, validating these ideas, interpreting results, and inspiring follow-up research. However, scientific…

Computation and Language · Computer Science 2024-06-11 Xingjian Zhang , Yutong Xie , Jin Huang , Jinge Ma , Zhaoying Pan , Qijia Liu , Ziyang Xiong , Tolga Ergen , Dongsub Shim , Honglak Lee , Qiaozhu Mei

The professionalism of a human doctor in outpatient service depends on two core abilities: the ability to make accurate medical decisions and the medical consultation skill to conduct strategic, empathetic patient inquiry. Existing Large…

Artificial Intelligence · Computer Science 2026-03-03 Yunghwei Lai , Kaiming Liu , Ziyue Wang , Weizhi Ma , Yang Liu

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

AI-assisted research is crossing a threshold: fully automated systems can now generate research papers for as little as $15, while long-horizon agents can execute experiments, draft manuscripts, and simulate critique with minimal human…

Systematic reviews (SRs) are vital for evidence-based practice in high stakes disciplines, such as healthcare, but are often impeded by intensive labors and lengthy processes that can take months to complete. Due to the high demand for…

Human-Computer Interaction · Computer Science 2025-06-03 Rui Qiu , Shijie Chen , Yu Su , Po-Yin Yen , Han-Wei Shen

Systematic literature review (SLR) is foundational to evidence-based research, enabling scholars to identify, classify, and synthesize existing studies to address specific research questions. Conducting an SLR is, however, largely a manual…