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In general, the rates of infection and removal (whether through recovery or death) are nonlinear functions of the number of infected and susceptible individuals. One of the simplest models for the spread of infectious diseases is the SIR…

Populations and Evolution · Quantitative Biology 2026-05-11 Seong Jun Park , M. Y. Choi

This paper investigates the optimal control of an epidemic governed by a SEIR model with an operational delay in vaccination. We address the mathematical challenge of imposing hard healthcare capacity constraints (e.g., ICU limits) over an…

Optimization and Control · Mathematics 2026-03-16 Behrooz Moosavi Ramezanzadeh

We investigate SIR models with vital dynamics, reinfection, and randomness at the transmission coefficient and recruitment rate. Initially, we conduct an extensive analysis of the autonomous scenario, covering aspects such as local and…

Dynamical Systems · Mathematics 2024-04-22 Javier López-de-la-Cruz , Alexandre N. Oliveira-Sousa

In this work, we use a new approach to study the spread of an infectious disease. Indeed, we study a SIR epidemic model with variable infectivity, where the individuals are distributed over a compact subset $D$ of $\R^d$. We define…

Probability · Mathematics 2025-11-18 Armand Kanga , Etienne Pardoux

Accurate identification of effective epidemic threshold is essential for understanding epidemic dynamics on complex networks. The existing studies on the effective epidemic threshold of the susceptible-infected-removed (SIR) model generally…

Physics and Society · Physics 2016-06-14 Panpan Shu , Wei Wang , Ming Tang , Pengcheng Zhao , Yi-Cheng Zhang

In this paper, we present a discrete-time networked SEIR model using population flow, its derivation, and assumptions under which this model is well defined. We identify properties of the system's equilibria, namely the healthy states. We…

Systems and Control · Electrical Eng. & Systems 2021-04-16 Brooks Butler , Ciyuan Zhang , Ian Walter , Nishant Nair , Raphael Stern , Philip E. Paré

This study develops and analyzes an extended Susceptible, Infected, Hospitalized and Recovered (SIHR) model incorporating time dependent control functions to capture preventive measures (e.g., distancing, mask use) and resource limited…

Populations and Evolution · Quantitative Biology 2025-10-01 Liban Ismail , Yahyeh Souleiman , Saraless Nadarajah , Abdisalam Hassan

Epidemic spreading and cascading failure are two important dynamical processes over complex networks. They have been investigated separately for a long history. But in the real world, these two dynamics sometimes may interact with each…

Physics and Society · Physics 2015-06-19 Lurong Jiang , Xinyu Jin , Yongxiang Xia , Bo Ouyang , Duanpo Wu

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

The Susceptible-Infected-Recovered (SIR) model is studied in multilayer networks with arbitrary number of links across the layers. By following the mapping to bond percolation we give the analytical expression for the epidemic threshold and…

Populations and Evolution · Quantitative Biology 2017-03-09 Ginestra Bianconi

Information spreading in a population can be modeled as an epidemic. Campaigners (e.g. election campaign managers, companies marketing products or movies) are interested in spreading a message by a given deadline, using limited resources.…

Systems and Control · Computer Science 2014-01-28 Kundan Kandhway , Joy Kuri

Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis

Effective containment of spreading processes such as epidemics requires accurate knowledge of several key parameters that govern their dynamics. In this work, we first show that the problem of identifying the underlying parameters of…

Systems and Control · Electrical Eng. & Systems 2023-11-03 Chi Ho Leung , William E. Retnaraj , Ashish R. Hota , Philip E. Paré

We study the Susceptible-Infected-Recovered model of epidemics in the vicinity of the threshold infectivity. We derive the distribution of total outbreak size in the limit of large population size $N$. This is accomplished by mapping the…

Populations and Evolution · Quantitative Biology 2009-11-13 David A. Kessler , Nadav M. Shnerb

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

Optimization and Control · Mathematics 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

In this work, the spread of a contagious disease on a society where the individuals may take precautions is modeled. The primary assumption is that the infected individuals transmit the infection to the susceptible members of the community…

Physics and Society · Physics 2021-03-16 Semra Gunduc

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

Threshold theorem is probably the most important development of mathematical epidemic modelling. Unfortunately, some models may not behave according to the threshold. In this paper, we will focus on the final outcome of SIR model with…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari