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Recent advancements in Mixed Integer Optimization (MIO) algorithms, paired with hardware enhancements, have led to significant speedups in resolving MIO problems. These strategies have been utilized for optimal subset selection,…

Methodology · Statistics 2024-03-27 Madhav Sankaranarayanan , Intekhab Hossain , Tom Chen

Observations consisting of measurements on relationships for pairs of objects arise in many settings, such as protein interaction and gene regulatory networks, collections of author-recipient email, and social networks. Analyzing such data…

Methodology · Statistics 2010-02-22 Edoardo M Airoldi , David M Blei , Stephen E Fienberg , Eric P Xing

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

Co-clustering is a data mining technique used to extract the underlying block structure between the rows and columns of a data matrix. Many approaches have been studied and have shown their capacity to extract such structures in continuous,…

Machine Learning · Computer Science 2022-12-23 Aichetou Bouchareb , Marc Boullé , Fabrice Clérot , Fabrice Rossi

Cluster-Weighted Modeling (CWM) is a flexible mixture approach for modeling the joint probability of data coming from a heterogeneous population as a weighted sum of the products of marginal distributions and conditional distributions. In…

Methodology · Statistics 2012-12-20 Salvatore Ingrassia , Simona C. Minotti , Antonio Punzo , Giorgio Vittadini

Matrix valued data has become increasingly prevalent in many applications. Most of the existing clustering methods for this type of data are tailored to the mean model and do not account for the dependence structure of the features, which…

Machine Learning · Statistics 2023-12-07 Inbeom Lee , Siyi Deng , Yang Ning

Clustering methods with dimension reduction have been receiving considerable wide interest in statistics lately and a lot of methods to simultaneously perform clustering and dimension reduction have been proposed. This work presents a novel…

Methodology · Statistics 2014-06-17 Michio Yamamoto , Kenichi Hayashi

Healthcare cost prediction is a challenging task due to the high-dimensionality and high correlation among covariates. Additionally, the skewed, heavy-tailed, and often multi-modal nature of cost data can complicate matters further due to…

Methodology · Statistics 2023-03-13 Zhengxiao Li , Yifan Huang , Yang Cao

We propose a semi-partitioned Generalized Method of Moments (GMM) framework for analyzing longitudinal data with time-dependent covariates, within a marginal modeling paradigm. This approach addresses limitations of both aggregated and…

Methodology · Statistics 2026-03-04 Niloofar Ramezani , Jeffrey R. Wilson

Unimodality constitutes a key property indicating grouping behavior of the data around a single mode of its density. We propose a method that partitions univariate data into unimodal subsets through recursive splitting around valley points…

Machine Learning · Computer Science 2024-12-23 Paraskevi Chasani , Aristidis Likas

We propose a new method for multivariate response regression and covariance estimation when elements of the response vector are of mixed types, for example some continuous and some discrete. Our method is based on a model which assumes the…

Methodology · Statistics 2022-03-04 Karl Oskar Ekvall , Aaron J. Molstad

Latent Class Models (LCMs) are used to cluster multivariate categorical data (e.g. group participants based on survey responses). Traditional LCMs assume a property called conditional independence. This assumption can be restrictive,…

Machine Learning · Statistics 2024-06-19 Jesse Bowers , Steve Culpepper

High-dimensional data of discrete and skewed nature is commonly encountered in high-throughput sequencing studies. Analyzing the network itself or the interplay between genes in this type of data continues to present many challenges. As…

Methodology · Statistics 2017-12-01 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Sanjeena Subedi

Exposure to diverse non-genetic factors, known as the exposome, is a critical determinant of health outcomes. However, analyzing the exposome presents significant methodological challenges, including: high collinearity among exposures, the…

Methodology · Statistics 2025-10-10 Matteo Amestoy , Mark van de Wiel , Jeroen Lakerveld , Wessel van Wieringen

Mixed linear regression (MLR) is a powerful model for characterizing nonlinear relationships by utilizing a mixture of linear regression sub-models. The identification of MLR is a fundamental problem, where most of the existing results…

Machine Learning · Statistics 2023-12-01 Yujing Liu , Zhixin Liu , Lei Guo

Recent years have seen a resurgence in interest in marketing mix models (MMMs), which are aggregate-level models of marketing effectiveness. Often these models incorporate nonlinear effects, and either implicitly or explicitly assume that…

Econometrics · Economics 2024-08-15 Ryan Dew , Nicolas Padilla , Anya Shchetkina

Learning energy-based model (EBM) requires MCMC sampling of the learned model as an inner loop of the learning algorithm. However, MCMC sampling of EBMs in high-dimensional data space is generally not mixing, because the energy function,…

Machine Learning · Statistics 2022-03-17 Erik Nijkamp , Ruiqi Gao , Pavel Sountsov , Srinivas Vasudevan , Bo Pang , Song-Chun Zhu , Ying Nian Wu

Motivated by high-throughput single-cell cytometry data with applications to vaccine development and immunological research, we consider statistical clustering in large-scale data that contain multiple rare clusters. We propose a new…

Methodology · Statistics 2016-06-30 Lin Lin , Jia Li

Handling missing data is a major challenge in model-based clustering, especially when the data exhibit skewness and heavy tails. We address this by extending the finite mixture of scale mixtures of multivariate skew-normal (FMSMSN) family…

Methodology · Statistics 2025-07-29 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

Predicting multiple real-world tasks in a single model often requires a particularly diverse feature space. Multimodal (MM) models aim to extract the synergistic predictive potential of multiple data types to create a shared feature space…

Machine Learning · Computer Science 2023-11-07 Vinitra Swamy , Malika Satayeva , Jibril Frej , Thierry Bossy , Thijs Vogels , Martin Jaggi , Tanja Käser , Mary-Anne Hartley
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