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Modeling complex spatiotemporal dynamical systems, such as the reaction-diffusion processes, have largely relied on partial differential equations (PDEs). However, due to insufficient prior knowledge on some under-explored dynamical…

Machine Learning · Computer Science 2023-05-23 Chengping Rao , Pu Ren , Qi Wang , Oral Buyukozturk , Hao Sun , Yang Liu

Using neural networks to solve partial differential equations (PDEs) is gaining popularity as an alternative approach in the scientific computing community. Neural networks can integrate different types of information into the loss…

Machine Learning · Computer Science 2024-05-07 Zhiwei Wang , Lulu Zhang , Zhongwang Zhang , Zhi-Qin John Xu

Deriving governing equations in Electromagnetic (EM) environment based on first principles can be quite tough when there are some unknown sources of noise and other uncertainties in the system. For nonlinear multiple-physics electromagnetic…

Computational Physics · Physics 2019-10-31 Bing Xiong , Haiyang Fu , Feng Xu , Yaqiu Jin

We introduce stochastic models of chemotaxis generalizing the deterministic Keller-Segel model. These models include fluctuations which are important in systems with small particle numbers or close to a critical point. Following Dean's…

Statistical Mechanics · Physics 2009-09-01 Pierre-Henri Chavanis

A significant advancement in Neural Network (NN) research is the integration of domain-specific knowledge through custom loss functions. This approach addresses a crucial challenge: how can models utilize physics or mathematical principles…

Machine Learning · Computer Science 2025-03-27 Seyedeh Azadeh Fallah Mortezanejad , Ruochen Wang , Ali Mohammad-Djafari

We develop a neuroevolution-potential (NEP) framework for generating neural network based machine-learning potentials. They are trained using an evolutionary strategy for performing large-scale molecular dynamics (MD) simulations. A…

Computational Physics · Physics 2022-01-25 Zheyong Fan , Zezhu Zeng , Cunzhi Zhang , Yanzhou Wang , Haikuan Dong , Yue Chen , Tapio Ala-Nissila

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

Traditionally, calcium dynamics in neurons are modeled using partial differential equations (PDEs) and ordinary differential equations (ODEs). The PDE component focuses on reaction-diffusion processes, while the ODE component addresses…

Numerical Analysis · Mathematics 2024-07-23 Abel Gurung , Qingguang Guan

The characterization of dynamical processes in living systems provides important clues for their mechanistic interpretation and link to biological functions. Thanks to recent advances in microscopy techniques, it is now possible to…

Data Analysis, Statistics and Probability · Physics 2023-11-29 Jesús Pineda , Benjamin Midtvedt , Harshith Bachimanchi , Sergio Noé , Daniel Midtvedt , Giovanni Volpe , Carlo Manzo

Partial differential equations often contain unknown functions that are difficult or impossible to measure directly, hampering our ability to derive predictions from the model. Workflows for recovering scalar PDE parameters from data are…

Machine Learning · Computer Science 2026-02-16 Torkel E. Loman , Yurij Salmaniw , Antonio Leon Villares , Jose A. Carrillo , Ruth E. Baker

In this work, we explore modeling change points in time-series data using neural stochastic differential equations (neural SDEs). We propose a novel model formulation and training procedure based on the variational autoencoder (VAE)…

Machine Learning · Computer Science 2025-06-16 Yousef El-Laham , Zhongchang Sun , Haibei Zhu , Tucker Balch , Svitlana Vyetrenko

We propose a neural network-based meta-learning method to efficiently solve partial differential equation (PDE) problems. The proposed method is designed to meta-learn how to solve a wide variety of PDE problems, and uses the knowledge for…

Machine Learning · Statistics 2023-10-23 Tomoharu Iwata , Yusuke Tanaka , Naonori Ueda

Partial differential equations (PDEs) underpin the modeling of many natural and engineered systems. It can be convenient to express such models as neural PDEs rather than using traditional numerical PDE solvers by replacing part or all of…

Machine Learning · Computer Science 2025-09-26 Sanket Jantre , Deepak Akhare , Zhiyuan Wang , Xiaoning Qian , Nathan M. Urban

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

We derive a mesoscopic modeling and simulation technique that is very close to the technique known as dissipative particle dynamics. The model is derived from molecular dynamics by means of a systematic coarse-graining procedure. Thus the…

Soft Condensed Matter · Physics 2009-10-31 Eirik G. Flekkoy , Peter V. Coveney , Gianni De Fabritiis

We present Neural Spectral Methods, a technique to solve parametric Partial Differential Equations (PDEs), grounded in classical spectral methods. Our method uses orthogonal bases to learn PDE solutions as mappings between spectral…

Machine Learning · Computer Science 2024-01-22 Yiheng Du , Nithin Chalapathi , Aditi Krishnapriyan

Learning the evolutionary dynamics of Partial Differential Equations (PDEs) is critical in understanding dynamic systems, yet current methods insufficiently learn their representations. This is largely due to the multi-scale nature of the…

Machine Learning · Computer Science 2024-10-16 Aoming Liang , Zhaoyang Mu , Pengxiao Lin , Cong Wang , Mingming Ge , Ling Shao , Dixia Fan , Hao Tang

Lipid nanoparticles (LNPs) are precisely engineered drug delivery carriers commonly produced through controlled mixing processes, such as nanoprecipitation. Since their delivery efficacy greatly depends on particle size, numerous studies…

Transfer learning for partial differential equations (PDEs) is to develop a pre-trained neural network that can be used to solve a wide class of PDEs. Existing transfer learning approaches require much information of the target PDEs such as…

Numerical Analysis · Mathematics 2023-01-30 Zezhong Zhang , Feng Bao , Lili Ju , Guannan Zhang

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru