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The ability to extrapolate gene expression dynamics in living single cells requires robust cell segmentation, and one of the challenges is the amorphous or irregularly shaped cell boundaries. To address this issue, we modified the U-Net…

Quantitative Methods · Quantitative Biology 2020-01-17 Nanyan Zhu , Chen Liu , Zakary S. Singer , Tal Danino , Andrew F. Laine , Jia Guo

Identifying biomarkers in medical images is vital for a wide range of biotech applications. However, recent Transformer and CNN based methods often struggle with variations in morphology and staining, which limits their feature extraction…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Saad Wazir , Daeyoung Kim

The U-net architecture has significantly impacted deep learning-based segmentation of medical images. Through the integration of long-range skip connections, it facilitated the preservation of high-resolution features. Out-of-distribution…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Frauke Wilm , Jonas Ammeling , Mathias Öttl , Rutger H. J. Fick , Marc Aubreville , Katharina Breininger

When some application scenarios need to use semantic segmentation technology, like automatic driving, the primary concern comes to real-time performance rather than extremely high segmentation accuracy. To achieve a good trade-off between…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Liang Liao , Liang Wan , Mingsheng Liu , Shusheng Li

Inner Retinal neurons are a most essential part of the retina and they are supplied with blood via retinal vessels. This paper primarily focuses on the segmentation of retinal vessels using a triple preprocessing approach. DRIVE database…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Mahendra Kumar Gourisaria , Vinayak Singh , Manoj Sahni

Retinal artery/vein (A/V) classification plays a critical role in the clinical biomarker study of how various systemic and cardiovascular diseases affect the retinal vessels. Conventional methods of automated A/V classification are…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Wenao Ma , Shuang Yu , Kai Ma , Jiexiang Wang , Xinghao Ding , Yefeng Zheng

Automated detection of curvilinear structures, e.g., blood vessels or nerve fibres, from medical and biomedical images is a crucial early step in automatic image interpretation associated to the management of many diseases. Precise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Lei Mou , Yitian Zhao , Huazhu Fu , Yonghuai Liu , Jun Cheng , Yalin Zheng , Pan Su , Jianlong Yang , Li Chen , Alejandro F Frang , Masahiro Akiba , Jiang Liu

In recent years, U-Net and its variants have been widely used in pathology image segmentation tasks. One of the key designs of U-Net is the use of skip connections between the encoder and decoder, which helps to recover detailed information…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Zongyi Li , Hongbing Lyu , Jun Wang

Accurate medical image segmentation requires effective modeling of both long-range dependencies and fine-grained boundary details. While transformers mitigate the issue of insufficient semantic information arising from the limited receptive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yanxin Li , Hui Wan , Libin Lan

This paper proposes a novel attention model for semantic segmentation, which aggregates multi-scale and context features to refine prediction. Specifically, the skeleton convolutional neural network framework takes in multiple different…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Shiqi Yang , Gang Peng

Recently, some pioneering works have preferred applying more complex modules to improve segmentation performances. However, it is not friendly for actual clinical environments due to limited computing resources. To address this challenge,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Jiacheng Ruan , Suncheng Xiang , Mingye Xie , Ting Liu , Yuzhuo Fu

Manually inspecting polyps from a colonoscopy for colorectal cancer or performing a biopsy on skin lesions for skin cancer are time-consuming, laborious, and complex procedures. Automatic medical image segmentation aims to expedite this…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Akib Mohammed Khan , Alif Ashrafee , Fahim Shahriar Khan , Md. Bakhtiar Hasan , Md. Hasanul Kabir

In medical imaging, there are clinically relevant segmentation tasks where the output mask is a projection to a subset of input image dimensions. In this work, we propose a novel convolutional neural network architecture that can…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Dmitrii Lachinov , Philipp Seeboeck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Semantic segmentation is a fundamental task in computer vision that involves dense pixel-wise classification for scene understanding. Despite significant progress, achieving high accuracy while maintaining real-time performance remains a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Abhinav Sagar

We propose a novel and flexible attention based U-Net architecture referred to as "Voxels-Intersecting Along Orthogonal Levels Attention U-Net" (viola-Unet), for intracranial hemorrhage (ICH) segmentation task in the INSTANCE 2022 Data…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Qinghui Liu , Bradley J MacIntosh , Till Schellhorn , Karoline Skogen , KyrreEeg Emblem , Atle Bjørnerud

In this paper we propose a novel deep learning-based algorithm for biomedical image segmentation which uses a sequential attention mechanism able to shift the focus of attention across the image in a selective way, allowing subareas which…

Computer Vision and Pattern Recognition · Computer Science 2019-09-30 Shohei Hayashi , Bisser Raytchev , Toru Tamaki , Kazufumi Kaneda

The accurate detection of lesion attributes is meaningful for both the computeraid diagnosis system and dermatologists decisions. However, unlike lesion segmentation and melenoma classification, there are few deep learning methods and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Xinzi He , Baiying Lei , Tianfu Wang

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Xiang He , Weiye Song , Yiming Wang , Fabio Poiesi , Ji Yi , Manishi Desai , Quanqing Xu , Kongzheng Yang , Yi Wan

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Convolutional neural networks like U-Net excel in medical image segmentation, while attention mechanisms and KAN enhance feature extraction. Meta's SAM 2 uses Vision Transformers for prompt-based segmentation without fine-tuning. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Mengyuan Liu , Yixiao Chen , Anning Tian , Xinmeng Wu , Mozhi Shen , Tianchou Gong , Jeongkyu Lee