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Multimodal large language models (MLLMs) show promising performance on medical visual question answering (VQA) and report generation, but these generation and explanation abilities do not reliably transfer to disease-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Li Wang , Xi Chen , XiangWen Deng , HuaHui Yi , ZeKun Jiang , Kang Li , Jian Li

Joint attention is a critical marker of early social-communicative development, yet remains difficult for caregivers to assess without expert guidance. In this work, we explore how multimodal large language models (MLLMs) can be aligned…

Human-Computer Interaction · Computer Science 2026-01-19 Weiyan Shi , Kenny Tsu Wei Choo

This paper explores the effectiveness of Multimodal Large Language models (MLLMs) as assistive technologies for visually impaired individuals. We conduct a user survey to identify adoption patterns and key challenges users face with such…

Adolescent Idiopathic Scoliosis (AIS) is a prevalent spinal deformity whose progression can be mitigated through early detection. Conventional screening methods are often subjective, difficult to scale, and reliant on specialized clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Dong Chen , Zizhuang Wei , Jialei Xu , Xinyang Sun , Zonglin He , Meiru An , Huili Peng , Yong Hu , Kenneth MC Cheung

While multimodal large language models (MLLMs) are increasingly applied in human-centred AI systems, their ability to understand complex social interactions remains uncertain. We present an exploratory study on aligning MLLMs with…

Human-Computer Interaction · Computer Science 2026-03-03 Weiyan Shi , Kenny Tsu Wei Choo

Multimodal large language models (MLLMs) have emerged as a promising paradigm for dental image analysis. However, their ability to capture the multi-level cognitive processes required for radiographic analysis remains unclear. Here, we…

Computation and Language · Computer Science 2026-05-11 Rongyang Wang , Shuang Zhou , Jiashuo Wang , Wenya Xie , Xiaoxia Che

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

Large language models (LLMs) and vision-augmented LLMs (VLMs) have significantly advanced medical informatics, diagnostics, and decision support. However, these models exhibit systematic biases, particularly age bias, compromising their…

Computers and Society · Computer Science 2025-08-28 Adil Bahaj , Oumaima Fadi , Mohamed Chetouani , Mounir Ghogho

Multimodal Large Language Models (MLLMs) have demonstrated robust capabilities in recognizing everyday human activities, yet their potential for analyzing clinically significant involuntary movements in neurological disorders remains…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Lina Zhang , Tonmoy Monsoor , Mehmet Efe Lorasdagi , Prateik Sinha , Chong Han , Peizheng Li , Yuan Wang , Jessica Pasqua , Colin McCrimmon , Rajarshi Mazumder , Vwani Roychowdhury

Adult neurodivergence, including Attention-Deficit/Hyperactivity Disorder (ADHD), high-functioning Autism Spectrum Disorder (ASD), and Cognitive Disengagement Syndrome (CDS), is marked by substantial symptom overlap that limits the…

Neurons and Cognition · Quantitative Biology 2026-01-23 Francesco Chiappone , Davide Marocco , Nicola Milano

Large Language Models (LLMs) have demonstrated remarkable proficiency in human interactions, yet their application within the medical field remains insufficiently explored. Previous works mainly focus on the performance of medical knowledge…

Computation and Language · Computer Science 2024-07-23 Yusheng Liao , Yutong Meng , Yuhao Wang , Hongcheng Liu , Yanfeng Wang , Yu Wang

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

With the rapid progress of large language models (LLMs), advanced multimodal large language models (MLLMs) have demonstrated impressive zero-shot capabilities on vision-language tasks. In the biomedical domain, however, even…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Siyuan Dai , Lunxiao Li , Kun Zhao , Eardi Lila , Paul K. Crane , Heng Huang , Dongkuan Xu , Haoteng Tang , Liang Zhan

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

Based on the foundation of Large Language Models (LLMs), Multilingual LLMs (MLLMs) have been developed to address the challenges faced in multilingual natural language processing, hoping to achieve knowledge transfer from high-resource…

Computation and Language · Computer Science 2024-12-10 Yuemei Xu , Ling Hu , Jiayi Zhao , Zihan Qiu , Kexin XU , Yuqi Ye , Hanwen Gu

In education, the traditional Automatic Short Answer Grading (ASAG) with feedback problem has focused primarily on evaluating text-only responses. However, real-world assessments often include multimodal responses containing both diagrams…

Artificial Intelligence · Computer Science 2026-02-06 Pritam Sil , Pushpak Bhattacharyya , Pawan Goyal , Ganesh Ramakrishnan

Multimodal Large Language Models (MLLMs) are increasingly used to interpret visualizations, yet little is known about why they fail. We present the first systematic analysis of barriers to visualization literacy in MLLMs. Using the…

Human-Computer Interaction · Computer Science 2026-01-21 Mengli , Duan , Yuhe , Jiang , Matthew Varona , Carolina Nobre

Multimodal Large Language Models (MLLMs) are increasingly applied in Personalized Image Aesthetic Assessment (PIAA) as a scalable alternative to expert evaluations. However, their predictions may reflect subtle biases influenced by…

Computation and Language · Computer Science 2025-09-16 Kun Li , Lai-Man Po , Hongzheng Yang , Xuyuan Xu , Kangcheng Liu , Yuzhi Zhao

Multimodal large language models (MLLMs) are changing how Blind and Low Vision (BLV) people access visual information. Unlike traditional visual interpretation tools that only provide descriptions, MLLM-enabled applications offer…

Human-Computer Interaction · Computer Science 2026-02-20 Ricardo E. Gonzalez Penuela , Crescentia Jung , Sharon Y Lin , Ruiying Hu , Shiri Azenkot

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang
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