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Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this…

Computation and Language · Computer Science 2023-12-21 Yan Cai , Linlin Wang , Ye Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

LLMs have demonstrated impressive performance in answering medical questions, such as achieving passing scores on medical licensing examinations. However, medical board exams or general clinical questions do not capture the complexity of…

Computation and Language · Computer Science 2026-02-19 Hanjie Chen , Zhouxiang Fang , Yash Singla , Mark Dredze

In recent years, pre-trained large language models (LLMs) have achieved tremendous success in the field of Natural Language Processing (NLP). Prior studies have primarily focused on general and generic domains, with relatively less research…

The recent success of large language models (LLMs) and the scaling law has led to a widespread adoption of larger models. Particularly in the healthcare industry, there is an increasing demand for locally operated LLMs due to security…

Computation and Language · Computer Science 2024-09-23 Issey Sukeda

Motivational interviewing (MI) promotes behavioural change in substance use disorders. Its fidelity is measured using the Motivational Interviewing Treatment Integrity (MITI) framework. While large language models (LLMs) can potentially…

Computation and Language · Computer Science 2026-03-05 Aishwariya Jha , Prakrithi Shivaprakash , Lekhansh Shukla , Animesh Mukherjee , Prabhat Chand , Pratima Murthy

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

The performance of Large Language Models (LLMs) on multiple-choice question (MCQ) benchmarks is frequently cited as proof of their medical capabilities. We hypothesized that LLM performance on medical MCQs may in part be illusory and driven…

Since the rise of large language models (LLMs), the domain adaptation has been one of the hot topics in various domains. Many medical LLMs trained with English medical dataset have made public recently. However, Japanese LLMs in medical…

Computation and Language · Computer Science 2024-06-24 Issey Sukeda , Risa Kishikawa , Satoshi Kodera

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Although both Google Gemini (1.5 Flash) and ChatGPT (4o and 4o-mini) give research quality evaluation scores that correlate positively with expert scores in nearly all fields, and more strongly that citations in most, it is not known…

Digital Libraries · Computer Science 2025-08-12 Mike Thelwall

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Large language models (LLMs) have pushed the limits of natural language understanding and exhibited excellent problem-solving ability. Despite the great success, most existing open-source LLMs (e.g., LLaMA-2) are still far away from…

Computation and Language · Computer Science 2024-05-06 Longhui Yu , Weisen Jiang , Han Shi , Jincheng Yu , Zhengying Liu , Yu Zhang , James T. Kwok , Zhenguo Li , Adrian Weller , Weiyang Liu

Our team participated in the BioASQ 2024 Task12b and Synergy tasks to build a system that can answer biomedical questions by retrieving relevant articles and snippets from the PubMed database and generating exact and ideal answers. We…

Computation and Language · Computer Science 2024-07-10 Wenxin Zhou , Thuy Hang Ngo

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

Artificial Intelligence · Computer Science 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber

Legal reasoning tasks present unique challenges for large language models (LLMs) due to the complexity of domain-specific knowledge and reasoning processes. This paper investigates how effectively smaller language models (Llama 2 7B and…

Machine Learning · Computer Science 2025-04-08 Rean Fernandes , André Biedenkapp , Frank Hutter , Noor Awad

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

The proliferation of Large Language Models (LLMs) presents transformative potential for healthcare, yet practical deployment is hindered by the absence of frameworks that assess real-world clinical utility. Existing benchmarks test static…

Large language models (LLMs) have rapidly advanced in clinical decision-making, yet the deployment of proprietary systems is hindered by privacy concerns and reliance on cloud-based infrastructure. Open-source alternatives allow local…

Computation and Language · Computer Science 2026-04-29 Alif Munim , Jun Ma , Omar Ibrahim , Alhusain Abdalla , Shuolin Yin , Leo Chen , Bo Wang
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