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Modern imaging instruments can produce terabytes to petabytes of data for a single experiment. The biggest barrier to processing big image datasets has been computational, where image analysis algorithms often lack the efficiency needed to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Nicholas Schaub , Andriy Kharchenko , Hamdah Abbasi , Sameeul Samee , Hythem Sidky , Nathan Hotaling

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

The random walker method for image segmentation is a popular tool for semi-automatic image segmentation, especially in the biomedical field. However, its linear asymptotic run time and memory requirements make application to 3D datasets of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Dominik Drees , Florian Eilers , Xiaoyi Jiang

We propose a software platform that integrates methods and tools for multi-objective parameter auto- tuning in tissue image segmentation workflows. The goal of our work is to provide an approach for improving the accuracy of nucleus/cell…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-09 Luis F. R. Taveira , Tahsin Kurc , Alba C. M. A. Melo , Jun Kong , Erich Bremer , Joel H. Saltz , George Teodoro

High-speed imaging of cells in flow is essential for probing cellular heterogeneity in large populations. Existing imaging approaches based on single-pixel detection and spatio-temporal encoding provide exceptional speed, but typically rely…

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

Image sensing often relies on a high-quality machine vision system with a large field of view and high resolution. It requires fine imaging optics, has high computational costs, and requires a large communication bandwidth between image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Xinrui Zhan , Xuyang Chang , Daoyu Li , Rong Yan , Yinuo Zhang , Liheng Bian

The open-source PyNX toolkit [Favre-Nicolin et al (2011) arXiv:1010.2641, Mandula et al (2016)] has been extended to provide tools for coherent X-ray imaging data analysis and simulation. All calculations can be executed on graphical…

Delineating and classifying individual cells in microscopy tissue images is inherently challenging yet remains essential for advancements in medical and neuroscientific research. In this work, we propose a new deep learning framework,…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Valentina Vadori , Jean-Marie Graïc , Antonella Peruffo , Giulia Vadori , Livio Finos , Enrico Grisan

Biomedical image segmentation is critical for precise structure delineation and downstream analysis. Traditional methods often struggle with noisy data, while deep learning models such as U-Net have set new benchmarks in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Shuo Zhao , Yu Zhou , Jianxu Chen

Label scarcity remains a major challenge in deep learning-based medical image segmentation. Recent studies use strong-weak pseudo supervision to leverage unlabeled data. However, performance is often hindered by inconsistencies between…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Zhiqiang Shen , Peng Cao , Xiaoli Liu , Jinzhu Yang , Osmar R. Zaiane

Many essential cellular functions depend on the viscoelastic properties of the cytoplasm. While techniques such as optical tweezers and atomic force microscopy can measure these properties, their reliance on localized probes prevents…

We present an end-to-end automated workflow that uses large-scale remote compute resources and an embedded GPU platform at the edge to enable AI/ML-accelerated real-time analysis of data collected for x-ray ptychography. Ptychography is a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Anakha V Babu , Tekin Bicer , Saugat Kandel , Tao Zhou , Daniel J. Ching , Steven Henke , Siniša Veseli , Ryan Chard , Antonino Miceli , Mathew Joseph Cherukara

The phase-field method has become a useful tool for the simulation of classical metallurgical phase transformations as well as other phenomena related to materials science. The thermodynamic consistency that forms the basis of these…

Cell image segmentation is usually implemented using fully supervised deep learning methods, which heavily rely on extensive annotated training data. Yet, due to the complexity of cell morphology and the requirement for specialized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Yu Zhu , Qiang Yang , Li Xu

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

The challenge of labeling large example datasets for computer vision continues to limit the availability and scope of image repositories. This research provides a new method for automated data collection, curation, labeling, and iterative…

Machine Learning · Computer Science 2023-01-20 Grant Rosario , David Noever , Matt Ciolino

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Deep learning models for pulmonary disease screening from Computed Tomography (CT) scans promise to alleviate the immense workload on radiologists. Still, their high computational cost, stemming from processing entire 3D volumes, remains a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Qian Shao , Bang Du , Yixuan Wu , Zepeng Li , Qiyuan Chen , Qianqian Tang , Jian Wu , Jintai Chen , Hongxia Xu

In recent years, an enormous amount of fluorescence microscopy images were collected in high-throughput lab settings. Analyzing and extracting relevant information from all images in a short time is almost impossible. Detecting tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Asmaa Haja , Lambert R. B. Schomaker