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Parameter estimation remains a challenging task across many areas of engineering. Because data acquisition can often be costly, limited, or prone to inaccuracies (noise, uncertainty) it is crucial to identify sensor configurations that…

Machine Learning · Statistics 2025-11-20 Georgios Venianakis , Constantinos Theodoropoulos , Michail Kavousanakis

One of the main goals of developmental biology is to reveal the gene regulatory networks (GRNs) underlying the robust differentiation of multipotent progenitors into precisely specified cell types. Most existing methods to infer GRNs from…

Quantitative Methods · Quantitative Biology 2024-01-23 Maria Mircea , Diego Garlaschelli , Stefan Semrau

Deep learning has been shown to be an effective tool in solving partial differential equations (PDEs) through physics-informed neural networks (PINNs). PINNs embed the PDE residual into the loss function of the neural network, and have been…

Machine Learning · Computer Science 2022-04-06 Jeremy Yu , Lu Lu , Xuhui Meng , George Em Karniadakis

Successfully training Physics Informed Neural Networks (PINNs) for highly nonlinear PDEs on complex 3D domains remains a challenging task. In this paper, PINNs are employed to solve the 3D incompressible Navier-Stokes (NS) equations at…

Computational Engineering, Finance, and Science · Computer Science 2024-08-23 Saakaar Bhatnagar , Andrew Comerford , Araz Banaeizadeh

Physics-informed neural networks (PINNs) constitute a flexible approach to both finding solutions and identifying parameters of partial differential equations. Most works on the topic assume noiseless data, or data contaminated with weak…

Machine Learning · Statistics 2024-06-21 Philipp Pilar , Niklas Wahlström

Engineering components must meet increasing technological demands in ever shorter development cycles. To face these challenges, a holistic approach is essential that allows for the concurrent development of part design, material system and…

Machine Learning · Computer Science 2024-07-31 Tobias Würth , Niklas Freymuth , Clemens Zimmerling , Gerhard Neumann , Luise Kärger

Accurate prediction of rarefied gas dynamics is crucial for optimizing flows through microelectromechanical systems, air filtration devices, and shale gas extraction. Traditional methods, such as discrete velocity and direct simulation…

Computational Physics · Physics 2025-01-24 Jean-Michel Tucny , Marco Lauricella , Mihir Durve , Gianmarco Guglielmo , Andrea Montessori , Sauro Succi

As a typical application of deep learning, physics-informed neural network (PINN) {has been} successfully used to find numerical solutions of partial differential equations (PDEs), but how to improve the limited accuracy is still a great…

Machine Learning · Computer Science 2022-08-09 Zhi-Yong Zhang , Hui Zhang , Li-Sheng Zhang , Lei-Lei Guo

Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

Physics-Informed Neural Networks (PINNs) have emerged as a powerful framework for solving partial differential equations (PDEs) by embedding physical laws into neural network training. However, traditional PINN models are typically designed…

Machine Learning · Computer Science 2025-05-05 Keon Vin Park

In the recent years, Physics Informed Neural Networks (PINNs) have received strong interest as a method to solve PDE driven systems, in particular for data assimilation purpose. This method is still in its infancy, with many shortcomings…

Machine Learning · Computer Science 2025-03-20 Nilo Schwencke , Cyril Furtlehner

Physics-informed neural networks (PINNs) are trained using physical equations and can also incorporate unmodeled effects by learning from data. PINNs for control (PINCs) of dynamical systems are gaining interest due to their prediction…

Systems and Control · Electrical Eng. & Systems 2024-08-29 Henrik Krauss , Tim-Lukas Habich , Max Bartholdt , Thomas Seel , Moritz Schappler

We introduce an optimized physics-informed neural network (PINN) trained to solve the problem of identifying and characterizing a surface breaking crack in a metal plate. PINNs are neural networks that can combine data and physics in the…

Machine Learning · Computer Science 2020-05-09 Khemraj Shukla , Patricio Clark Di Leoni , James Blackshire , Daniel Sparkman , George Em Karniadakis

Turbulence remains a problem that is yet to be fully understood, with experimental and numerical studies aiming to fully characterise the statistical properties of turbulent flows. Such studies require huge amount of resources to capture,…

Fluid Dynamics · Physics 2022-05-31 Vijay Kag , Kannabiran Seshasayanan , Venkatesh Gopinath

Physics-Informed Neural Networks (PINNs) are a class of deep learning neural networks that learn the response of a physical system without any simulation data, and only by incorporating the governing partial differential equations (PDEs) in…

Machine Learning · Computer Science 2023-12-19 Rini J. Gladstone , Mohammad A. Nabian , N. Sukumar , Ankit Srivastava , Hadi Meidani

Physics-informed neural networks (PINNs) effectively embed physical principles into machine learning, but often struggle with complex or alternating geometries. We propose a novel method for integrating geometric transformations within…

Machine Learning · Computer Science 2023-11-30 Samuel Burbulla

Physics-informed neural networks (PINNs) were recently proposed in [1] as an alternative way to solve partial differential equations (PDEs). A neural network (NN) represents the solution while a PDE-induced NN is coupled to the solution NN,…

Computational Physics · Physics 2019-10-22 Xiaoli Chen , Jinqiao Duan , George Em Karniadakis

Physics-informed neural networks (PINNs) have garnered significant interest for their potential in solving partial differential equations (PDEs) that govern a wide range of physical phenomena. By incorporating physical laws into the…

Machine Learning · Computer Science 2026-04-24 Jian Cheng Wong , Isaac Yin Chung Lai , Pao-Hsiung Chiu , Chin Chun Ooi , Abhishek Gupta , Yew-Soon Ong

Physics-informed neural networks (PINNs) have emerged as a powerful approach for solving partial differential equations (PDEs) by training neural networks with loss functions that incorporate physical constraints. In this work, we introduce…

Machine Learning · Computer Science 2026-01-29 Madison Cooley , Robert M. Kirby , Shandian Zhe , Varun Shankar

Physics-informed neural networks (PINNs) have shown promising potential for solving partial differential equations (PDEs) using deep learning. However, PINNs face training difficulties for evolutionary PDEs, particularly for dynamical…

Neural and Evolutionary Computing · Computer Science 2023-12-25 Siqi Chen , Bin Shan , Ye Li