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Large language models (LLMs) have demonstrated strong capabilities in language understanding and reasoning, yet they remain limited when tackling real-world tasks that require up-to-date knowledge, precise operations, or specialized tool…

Machine Learning · Computer Science 2025-09-17 Yabo Zhang , Yihan Zeng , Qingyun Li , Zhen Hu , Kavin Han , Wangmeng Zuo

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

Reasoning-focused large language models (LLMs) are rapidly evolving across various domains, yet their capabilities in handling complex legal problems remains underexplored. In this paper, we introduce Unilaw-R1, a large language model…

Computation and Language · Computer Science 2025-12-09 Hua Cai , Shuang Zhao , Liang Zhang , Xuli Shen , Qing Xu , Weilin Shen , Zihao Wen , Tianke Ban

Large Language Models (LLMs) exhibit remarkable capabilities but are prone to generating inaccurate or hallucinatory responses. This limitation stems from their reliance on vast pretraining datasets, making them susceptible to errors in…

Computation and Language · Computer Science 2024-04-02 Chi-Min Chan , Chunpu Xu , Ruibin Yuan , Hongyin Luo , Wei Xue , Yike Guo , Jie Fu

Argument mining (AM) is an interdisciplinary research field that integrates insights from logic, philosophy, linguistics, rhetoric, law, psychology, and computer science. It involves the automatic identification and extraction of…

Computation and Language · Computer Science 2025-07-25 Marcin Pietroń , Rafał Olszowski , Jakub Gomułka , Filip Gampel , Andrzej Tomski

The rapid advancement of Large Language Models (LLMs) in the realm of mathematical reasoning necessitates comprehensive evaluations to gauge progress and inspire future directions. Existing assessments predominantly focus on problem-solving…

Computation and Language · Computer Science 2024-06-05 Xiaoyuan Li , Wenjie Wang , Moxin Li , Junrong Guo , Yang Zhang , Fuli Feng

Large Language Models (LLMs) excel at generating synthetic data, but ensuring its quality and diversity remains challenging. We propose Genetic Prompt, a novel framework that combines genetic algorithms with LLMs to augment synthetic data…

Computation and Language · Computer Science 2025-09-03 Guangzeng Han , Weisi Liu , Xiaolei Huang

Large language models (LLMs), such as LLaMA, Alpaca, Vicuna, GPT-3.5 and GPT-4, have advanced the performance of AI systems on various natural language processing tasks to human-like levels. However, their generalisation and robustness when…

Computation and Language · Computer Science 2025-01-20 Qiming Bao , Gael Gendron , Alex Yuxuan Peng , Wanjun Zhong , Neset Tan , Yang Chen , Michael Witbrock , Jiamou Liu

Reinforcement Learning (RL) has demonstrated significant potential in certain real-world industrial applications, yet its broader deployment remains limited by inherent challenges such as sample inefficiency and unstable learning dynamics.…

Machine Learning · Computer Science 2025-07-03 Tom Maus , Asma Atamna , Tobias Glasmachers

Drug discovery is a complex and resource-intensive process, making early prediction of approval outcomes critical for optimizing research investments. While classical machine learning and deep learning methods have shown promise in drug…

Large language models (LLMs) have recently shown strong reasoning abilities in domains like mathematics, coding, and scientific problem-solving, yet their potential for ranking tasks, where prime examples include retrieval, recommender…

Information Retrieval · Computer Science 2025-10-17 Tao Feng , Zhigang Hua , Zijie Lei , Yan Xie , Shuang Yang , Bo Long , Jiaxuan You

In recent years, the development of Large Language Models (LLMs) has made significant breakthroughs in the field of natural language processing and has gradually been applied to the field of humanities and social sciences research. LLMs…

Computers and Society · Computer Science 2025-04-16 Peiran Gu , Fuhao Duan , Wenhao Li , Bochen Xu , Ying Cai , Teng Yao , Chenxun Zhuo , Tianming Liu , Bao Ge

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

The growing integration of vision-language models (VLMs) in medical applications offers promising support for diagnostic reasoning. However, current medical VLMs often face limitations in generalization, transparency, and computational…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Tan-Hanh Pham , Chris Ngo

The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…

Quantitative Methods · Quantitative Biology 2024-01-19 Jiayu Chang , Shiyu Wang , Chen Ling , Zhaohui Qin , Liang Zhao

Gene set analysis is a mainstay of functional genomics, but it relies on curated databases of gene functions that are incomplete. Here we evaluate five Large Language Models (LLMs) for their ability to discover the common biological…

Root Cause Analysis (RCA) in mobile networks remains a challenging task due to the need for interpretability, domain expertise, and causal reasoning. In this work, we propose a lightweight framework that leverages Large Language Models…

Artificial Intelligence · Computer Science 2025-07-30 Mohamed Sana , Nicola Piovesan , Antonio De Domenico , Yibin Kang , Haozhe Zhang , Merouane Debbah , Fadhel Ayed

Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

Genomics · Quantitative Biology 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

This paper introduces a reinforcement learning (RL) approach to address the challenges associated with configuring and optimizing genetic algorithms (GAs) for solving difficult combinatorial or non-linear problems. The proposed RL+GA method…