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In computational chemistry, crystal structure prediction (CSP) is an optimization problem that involves discovering the lowest energy stable crystal structure for a given chemical formula. This problem is challenging as it requires…

Machine Learning · Computer Science 2023-10-17 Han Qi , Xinyang Geng , Stefano Rando , Iku Ohama , Aviral Kumar , Sergey Levine

Accurate and fast prediction of materials properties is central to the digital transformation of materials design. However, the vast design space and diverse operating conditions pose significant challenges for accurately modeling arbitrary…

We present a high-throughput, end-to-end pipeline for organic crystal structure prediction (CSP) -- the problem of identifying the stable crystal structures that will form from a given molecule based only on its molecular composition. Our…

Materials Science · Physics 2023-12-12 Amit Kadan , Kevin Ryczko , Andrew Wildman , Rodrigo Wang , Adrian Roitberg , Takeshi Yamazaki

Crystal Structure Prediction (CSP) aims to discover solid crystalline materials by optimizing periodic arrangements of atoms, ions or molecules. CSP takes weeks of supercomputer time because of slow energy minimizations for millions of…

Materials Science · Physics 2021-08-17 Jakob Ropers , Marco M Mosca , Olga Anosova , Vitaliy Kurlin , Andrew I Cooper

Crystalline materials can form different structural arrangements (i.e. polymorphs) with the same chemical composition, exhibiting distinct physical properties depending on how they were synthesized or the conditions under which they…

Materials Science · Physics 2025-06-16 Sadman Sadeed Omee , Lai Wei , Sourin Dey , Jianjun Hu

The ability to reliably predict the structures and stabilities of a molecular crystal and its polymorphs without any prior experimental information would be an invaluable tool for a number of fields, with specific and immediate applications…

Stress hotspots are regions of stress concentrations that form under deformation in polycrystalline materials. We use a machine learning approach to study the effect of preferred slip systems and microstructural features that reflect local…

Materials Science · Physics 2018-04-18 Ankita Mangal , Elizabeth A. Holm

Computational prediction of stable crystal structures has a profound impact on the large-scale discovery of novel functional materials. However, predicting the crystal structure solely from a material's composition or formula is a promising…

Materials Science · Physics 2024-04-09 Yuqi Song , Rongzhi Dong , Lai Wei , Qin Li , Jianjun Hu

Crystal Structure Prediction (CSP) is crucial in various scientific disciplines. While CSP can be addressed by employing currently-prevailing generative models (e.g. diffusion models), this task encounters unique challenges owing to the…

Materials Science · Physics 2024-03-08 Rui Jiao , Wenbing Huang , Peijia Lin , Jiaqi Han , Pin Chen , Yutong Lu , Yang Liu

Crystal structure prediction (CSP) has emerged as one of the most important approaches for discovering new materials. CSP algorithms based on evolutionary algorithms and particle swarm optimization have discovered a great number of new…

Materials Science · Physics 2022-04-06 Wenhui Yang , Edirisuriya M. Dilanga Siriwardane , Jianjun Hu

A thorough in situ characterization of materials at extreme conditions is challenging, and computational tools such as crystal structural search methods in combination with ab initio calculations are widely used to guide experiments by…

Materials Science · Physics 2018-11-14 Maximilian Amsler , Vinay I. Hegde , Steven D. Jacobsen , Chris Wolverton

The discovery of new materials using crystal structure prediction (CSP) based on generative machine learning models has become a significant research topic in recent years. In this paper, we study invariance and continuity in the generative…

Machine Learning · Computer Science 2025-02-05 Yuji Tone , Masatoshi Hanai , Mitsuaki Kawamura , Kenjiro Taura , Toyotaro Suzumura

Novel materials drive advancements in fields ranging from energy storage to electronics, with crystal structure characterization forming a crucial yet challenging step in materials discovery. In this work, we introduce \emph{deCIFer}, an…

Crystal plasticity (CP) simulations are a tool for understanding how microstructure morphology and texture affect mechanical properties and are an essential component of elucidating the structure-property relations. However, it can be…

Computational Engineering, Finance, and Science · Computer Science 2024-06-17 Junyan He , Deepankar Pal , Ali Najafi , Diab Abueidda , Seid Koric , Iwona Jasiuk

This work presents a machine learning approach to predict peak-stress clusters in heterogeneous polycrystalline materials. Prior work on using machine learning in the context of mechanics has largely focused on predicting the effective…

Analysis of PDEs · Mathematics 2024-05-10 Ankit Shrivastava , Jingxiao Liu , Kaushik Dayal , Hae Young Noh

Atomic-level modeling performed at large scales enables the investigation of mesoscale materials properties with atom-by-atom resolution. The spatial complexity of such cross-scale simulations renders them unsuitable for simple human visual…

Materials Science · Physics 2022-04-05 Heejung Chung , Rodrigo Freitas , Gowoon Cheon , Evan J. Reed

Crystalline materials are widely used in technological applications, yet their discovery remains a significant challenge. As their properties are driven by structure, crystal structure prediction (CSP) methods play a central role in…

Machine Learning · Computer Science 2026-04-28 Stavros Gerolymatos , J. Kyle Brubaker , Martin J. A. Schuetz , Vladimir V. Gusev

Understanding structure-property relationships is an essential yet challenging aspect of materials discovery and development. To facilitate this process, recent studies in materials informatics have sought latent embedding spaces of crystal…

Machine Learning · Computer Science 2025-06-23 Yuta Suzuki , Tatsunori Taniai , Ryo Igarashi , Kotaro Saito , Naoya Chiba , Yoshitaka Ushiku , Kanta Ono

Crystal structure forms the foundation for understanding the physical and chemical properties of materials. Generative models have emerged as a new paradigm in crystal structure prediction(CSP), however, accurately capturing key…

Materials Science · Physics 2025-02-14 Ziyi Chen , Yang Yuan , Siming Zheng , Jialong Guo , Sihan Liang , Yangang Wang , Zongguo Wang

In addressing the challenge of Crystal Structure Prediction (CSP), symmetry-aware deep learning models, particularly diffusion models, have been extensively studied, which treat CSP as a conditional generation task. However, ensuring…

Materials Science · Physics 2025-12-09 Peijia Lin , Pin Chen , Rui Jiao , Qing Mo , Jianhuan Cen , Wenbing Huang , Yang Liu , Dan Huang , Yutong Lu