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High Performance Computing is notorious for its long and expensive software development cycle. To address this challenge, we present Bind: a "partitioned global workflow" parallel programming model for C++ applications that enables quick…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-16 Alex Kosenkov , Matthias Troyer

Modern cloud inference creates a two sided privacy problem where users reveal sensitive inputs to providers, while providers must execute proprietary model weights inside potentially leaky execution environments. Fully homomorphic…

Cryptography and Security · Computer Science 2026-03-24 Bernardo Magri , Benjamin Marsh , Paul Gebheim

With the continuous advancement of processors, modern micro-architecture designs have become increasingly complex. The vast design space presents significant challenges for human designers, making design space exploration (DSE) algorithms a…

Machine Learning · Computer Science 2024-12-17 Hanwei Fan , Ya Wang , Sicheng Li , Tingyuan Liang , Wei Zhang

Quantum algorithms for computational linear algebra promise up to exponential speedups for applications such as simulation and regression, making them prime candidates for hardware realization. But these algorithms execute in a model that…

Programming Languages · Computer Science 2026-05-14 Charles Yuan

We present PINNACLE, an open-source computational framework for physics-informed neural networks (PINNs) that integrates modern training strategies, multi-GPU acceleration, and hybrid quantum-classical architectures within a unified modular…

Machine Learning · Computer Science 2026-04-20 Shimon Pisnoy , Hemanth Chandravamsi , Ziv Chen , Aaron Goldgewert , Gal Shaviner , Boris Shragner , Steven H. Frankel

In cryptographic engineering, extensive attention has been devoted to ameliorating the performance and security of the algorithms within. Nonetheless, in the state-of-the-art, the approaches for increasing the reliability of the efficient…

Cryptography and Security · Computer Science 2018-04-19 Mehran Mozaffari Kermani , Reza Azarderakhsh , Siavash Bayat-Sarmadi

Integrating security into agile software development is an open issue for research and practice. Especially in strongly regulated industries, complexity increases not only when scaling agile practices but also when aiming for compliance…

Software Engineering · Computer Science 2021-05-31 Fabiola Moyón , Daniel Méndez Fernández , Kristian Beckers , Sebastian Klepper

Binary code analysis is widely used to assess a program's correctness, performance, and provenance. Binary analysis applications often construct control flow graphs, analyze data flow, and use debugging information to understand how machine…

Domain-specific software and hardware co-design is encouraging as it is much easier to achieve efficiency for fewer tasks. Agile domain-specific benchmarking speeds up the process as it provides not only relevant design inputs but also…

We propose a novel hardware and software co-exploration framework for efficient neural architecture search (NAS). Different from existing hardware-aware NAS which assumes a fixed hardware design and explores the neural architecture search…

Machine Learning · Computer Science 2020-01-14 Weiwen Jiang , Lei Yang , Edwin Sha , Qingfeng Zhuge , Shouzhen Gu , Sakyasingha Dasgupta , Yiyu Shi , Jingtong Hu

In order to mitigate the security threat of quantum computers, NIST is undertaking a process to standardize post-quantum cryptosystems, aiming to assess their security and speed up their adoption in production scenarios. Several hardware…

Hardware Architecture · Computer Science 2023-01-10 Gabriele Montanaro , Andrea Galimberti , Ernesto Colizzi , Davide Zoni

Co-design optimisation of autonomous systems has emerged as a powerful alternative to sequential approaches by jointly optimising physical design and control strategies. However, existing frameworks often neglect the robustness required for…

Robotics · Computer Science 2026-03-13 Adrian Andrei Buda , Xavier Chen , Nicolò Botteghi , Urban Fasel

The binary similarity problem consists in determining if two functions are similar by only considering their compiled form. Advanced techniques for binary similarity recently gained momentum as they can be applied in several fields, such as…

Cryptography and Security · Computer Science 2019-12-20 Luca Massarelli , Giuseppe Antonio Di Luna , Fabio Petroni , Leonardo Querzoni , Roberto Baldoni

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

Analog circuit design is a time-consuming, experience-driven task in chip development. Despite advances in AI, developing universal, fast, and stable gate sizing methods for analog circuits remains a significant challenge. Recent approaches…

Artificial Intelligence · Computer Science 2025-08-08 Xinyue Wu , Fan Hu , Shaik Jani Babu , Yi Zhao , Xinfei Guo

This paper addresses efficient hardware/software implementation approaches for the AES (Advanced Encryption Standard) algorithm and describes the design and performance testing algorithm for embedded system. Also, with the spread of…

Cryptography and Security · Computer Science 2009-09-15 Zine El Abidine Alaoui Ismaili , Ahmed Moussa

The in silico design of peptides and proteins as binders is useful for diagnosis and therapeutics due to their low adverse effects and major specificity. To select the most promising candidates, a key matter is to understand their…

Biomolecules · Quantitative Biology 2021-02-03 Rodrigo Ochoa , Miguel A. Soler , Alessandro Laio , Pilar Cossio

Fully Homomorphic Encryption (FHE) enables computation directly on encrypted data but incurs massive computational and memory overheads, often exceeding plaintext execution by several orders of magnitude. While custom ASIC accelerators can…

While many hardware accelerators have recently been proposed to address the inefficiency problem of fully homomorphic encryption (FHE) schemes, none of them is able to deliver optimal performance when facing real-world FHE workloads…

Hardware Architecture · Computer Science 2025-01-31 Junxue Zhang , Xiaodian Cheng , Gang Cao , Meng Dai , Yijun Sun , Han Tian , Dian Shen , Yong Wang , Kai Chen

This article presents an asynchronous FPGA architecture for implementing cryptographic algorithms secured against physical cryptanalysis. We discuss the suitability of asynchronous reconfigurable architectures for such applications before…