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The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

For computational efficiency, surrogate models have been used to emulate mathematical simulators for physical or biological processes. High-speed simulation is crucial for conducting uncertainty quantification (UQ) when the simulation is…

Machine Learning · Computer Science 2022-11-21 Lixiang Zhang , Jia Li

Many real-world systems are modelled using complex ordinary differential equations (ODEs). However, the dimensionality of these systems can make them challenging to analyze. Dimensionality reduction techniques like Proper Orthogonal…

Computational Engineering, Finance, and Science · Computer Science 2025-02-26 Abhishek Ajayakumar , Soumyendu Raha

Many applications, such as autonomous driving, heavily rely on multi-modal data where spatial alignment between the modalities is required. Most multi-modal registration methods struggle computing the spatial correspondence between the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Moab Arar , Yiftach Ginger , Dov Danon , Ilya Leizerson , Amit Bermano , Daniel Cohen-Or

Recent deep learning models can efficiently combine inputs from different modalities (e.g., images and text) and learn to align their latent representations, or to translate signals from one domain to another (as in image captioning, or…

Artificial Intelligence · Computer Science 2025-11-27 Benjamin Devillers , Léopold Maytié , Rufin VanRullen

Methods for medical image registration infer geometric transformations that align pairs/groups of images by maximising an image similarity metric. This problem is ill-posed as several solutions may have equivalent likelihoods, also…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Aisha L. Shuaibu , Ivor J. A. Simpson

Deformable image registration, estimating the spatial transformation between different images, is an important task in medical imaging. Many previous studies have used learning-based methods for multi-stage registration to perform 3D image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jian-Qing Zheng , Ziyang Wang , Baoru Huang , Ngee Han Lim , Tonia Vincent , Bartlomiej W. Papiez

The performance of machine learning surrogates is critically dependent on data quality and quantity. This presents a major challenge, as high-fidelity (HF) data is often scarce and computationally expensive to acquire, while low-fidelity…

Machine Learning · Computer Science 2026-02-03 Jice Zeng , David Barajas-Solano , Hui Chen

With computational models becoming more expensive and complex, surrogate models have gained increasing attention in many scientific disciplines and are often necessary to conduct sensitivity studies, parameter optimization etc. In the…

Methodology · Statistics 2023-07-24 Matthias Fischer , Carsten Proppe

Inverse modeling for computing a high-dimensional spatially-varying property field from indirect sparse and noisy observations is a challenging problem. This is due to the complex physical system of interest often expressed in the form of…

Computational Physics · Physics 2021-02-22 Govinda Anantha Padmanabha , Nicholas Zabaras

In the continual effort to improve product quality and decrease operations costs, computational modeling is increasingly being deployed to determine feasibility of product designs or configurations. Surrogate modeling of these computer…

Machine Learning · Statistics 2021-11-10 Nathan Wycoff , Mickaël Binois , Robert B. Gramacy

Medical image registration aims at identifying the spatial deformation between images of the same anatomical region and is fundamental to image-based diagnostics and therapy. To date, the majority of the deep learning-based registration…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Anna Reithmeir , Julia A. Schnabel , Veronika A. Zimmer

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

Self-supervised, multi-modal learning has been successful in holistic representation of complex scenarios. This can be useful to consolidate information from multiple modalities which have multiple, versatile uses. Its application in…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aniruddha Tamhane , Jie Ying Wu , Mathias Unberath

Developing surrogates for computer models has become increasingly important for addressing complex problems in science and engineering. This article introduces an artificial intelligent (AI) surrogate, referred to as the DeepSurrogate, for…

Deformable registration has been one of the pillars of biomedical image computing. Conventional approaches refer to the definition of a similarity criterion that, once endowed with a deformation model and a smoothness constraint, determines…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Enzo Ferrante , Puneet K. Dokania , Rafael Marini Silva , Nikos Paragios

Computer vision and machine learning are playing an increasingly important role in computer-assisted diagnosis; however, the application of deep learning to medical imaging has challenges in data availability and data imbalance, and it is…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Kai Ma , Siyuan He , Pengcheng Xi , Ashkan Ebadi , Stéphane Tremblay , Alexander Wong

We present recursive cascaded networks, a general architecture that enables learning deep cascades, for deformable image registration. The proposed architecture is simple in design and can be built on any base network. The moving image is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Shengyu Zhao , Yue Dong , Eric I-Chao Chang , Yan Xu

We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Julian Krebs , Tommaso Mansi , Boris Mailhé , Nicholas Ayache , Hervé Delingette

Foundation models trained as autoregressive PDE surrogates hold significant promise for accelerating scientific discovery through their capacity to both extrapolate beyond training regimes and efficiently adapt to downstream tasks despite a…