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Multimodal neuroimaging analysis often involves complex, modality-specific preprocessing workflows that require careful configuration, quality control, and coordination across heterogeneous toolchains. Beyond preprocessing, downstream…

Artificial Intelligence · Computer Science 2026-05-08 Lujia Zhong , Yihao Xia , Jianwei Zhang , Shuo huang , Jiaxin Yue , Mingyang Xia , Yonggang Shi

Agents based on large language models have shown great potential in accelerating scientific discovery by leveraging their rich background knowledge and reasoning capabilities. In this paper, we introduce BioDiscoveryAgent, an agent that…

Artificial Intelligence · Computer Science 2025-03-11 Yusuf Roohani , Andrew Lee , Qian Huang , Jian Vora , Zachary Steinhart , Kexin Huang , Alexander Marson , Percy Liang , Jure Leskovec

The advancement of Large Language Models (LLMs) enables flexible and interpretable automatic evaluations. In the field of machine translation evaluation, utilizing LLMs with translation error annotations based on Multidimensional Quality…

Computation and Language · Computer Science 2025-09-17 Shijie Zhang , Renhao Li , Songsheng Wang , Philipp Koehn , Min Yang , Derek F. Wong

In this paper, we consider a mixed-prompt scenario for a large language model (LLM) inference serving system that supports diverse applications with both short prompts and long prompts and heterogeneous SLOs for iteration time. To improve…

Computation and Language · Computer Science 2025-03-19 Haiying Shen , Tanmoy Sen

Predicting gene regulation responses to biological perturbations requires reasoning about underlying biological causalities. While large language models (LLMs) show promise for such tasks, they are often overwhelmed by the entangled nature…

Artificial Intelligence · Computer Science 2026-05-01 Hyomin Kim , Sang-Yeon Hwang , Jaechang Lim , Yinhua Piao , Yunhak Oh , Woo Youn Kim , Chanyoung Park , Sungsoo Ahn , Junhyeok Jeon

Emerging 6G networks rely on complex cross-layer optimization, yet manually translating high-level intents into mathematical formulations remains a bottleneck. While Large Language Models (LLMs) offer promise, monolithic approaches often…

Artificial Intelligence · Computer Science 2026-01-28 Haoyun Li , Ming Xiao , Kezhi Wang , Robert Schober , Dong In Kim , Yong Liang Guan

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

The latent class model is a widely used mixture model for multivariate discrete data. Besides the existence of qualitatively heterogeneous latent classes, real data often exhibit additional quantitative heterogeneity nested within each…

Methodology · Statistics 2025-01-23 Zhongyuan Lyu , Ling Chen , Yuqi Gu

The pace of scientific research, vital for improving human life, is complex, slow, and needs specialized expertise. Meanwhile, novel, impactful research often stems from both a deep understanding of prior work, and a cross-pollination of…

Computation and Language · Computer Science 2025-02-11 Jinheon Baek , Sujay Kumar Jauhar , Silviu Cucerzan , Sung Ju Hwang

Large language models (LLMs) show promise for healthcare question answering, but clinical use is limited by weak verification, insufficient evidence grounding, and unreliable confidence signalling. We propose a multi-agent medical QA…

Computation and Language · Computer Science 2026-02-17 Naeimeh Nourmohammadi , Md Meem Hossain , The Anh Han , Safina Showkat Ara , Zia Ush Shamszaman

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Alvaro Lopez Pellicer , Plamen Angelov , Marwan Bukhari , Yi Li , Eduardo Soares , Jemma Kerns

Reward Modeling is critical in evaluating and improving the generation of Large Language Models (LLMs). While numerous recent works have shown its feasibility in improving safety, helpfulness, reasoning, and instruction-following ability,…

Computation and Language · Computer Science 2025-11-13 Hanning Zhang , Juntong Song , Juno Zhu , Yuanhao Wu , Tong Zhang , Cheng Niu

Comprehending genomic information is essential for biomedical research, yet extracting data from complex distributed databases remains challenging. Large language models (LLMs) offer potential for genomic Question Answering (QA) but face…

Artificial Intelligence · Computer Science 2026-01-16 Kimia Abedini , Farzad Shami , Gianmaria Silvello

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

Artificial Intelligence · Computer Science 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be…

Artificial Intelligence · Computer Science 2024-07-16 Yihang Xiao , Jinyi Liu , Yan Zheng , Xiaohan Xie , Jianye Hao , Mingzhi Li , Ruitao Wang , Fei Ni , Yuxiao Li , Jintian Luo , Shaoqing Jiao , Jiajie Peng

Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures. However, annotating these signatures-especially those involving poorly characterized genes-remains a major challenge.…

In recent times, the emergence of Large Language Models (LLMs) has resulted in increasingly larger model size, posing challenges for inference on low-resource devices. Prior approaches have explored offloading to facilitate low-memory…

Performance · Computer Science 2024-03-05 Xuanlei Zhao , Bin Jia , Haotian Zhou , Ziming Liu , Shenggan Cheng , Yang You

In language processing, training data with extremely large variance may lead to difficulty in the language model's convergence. It is difficult for the network parameters to adapt sentences with largely varied semantics or grammatical…

Computation and Language · Computer Science 2022-05-26 Yunhao Yang , Zhaokun Xue

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

Tracking how data is mentioned and used in research papers provides critical insights for improving data discoverability, quality, and production. However, manually identifying and classifying dataset mentions across vast academic…

Computation and Language · Computer Science 2025-02-17 Aivin V. Solatorio , Rafael Macalaba , James Liounis