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We present a continuous-wave, post selection-free implementation of a widefield optical multipass microscope. It can be operated with a spatially and temporally incoherent light source, and requires no active outcoupling or exotic detection…

Optics · Physics 2021-07-13 Brannon B. Klopfer , Mark A. Kasevich

Reactive flows in porous media play an important role in our life and are crucial for many industrial, environmental and biomedical applications. Very often the concentration of the species at the inlet is known, and the so-called…

Fluid Dynamics · Physics 2023-01-13 Daria Fokina , Pavel Toktaliev , Oleg Iliev , Ivan Oseledets

In this letter, we describe the capillary sorting of particles by size based on dip coating. A substrate withdrawn from a liquid bath entrains a coating whose thickness depends on the withdrawal speed and the liquid properties. If the…

Soft Condensed Matter · Physics 2020-11-04 Brian M. Dincau , Martin Z. Bazant , Emilie Dressaire , Alban Sauret

Inspired by the capability of structured illumination microscopy in subwavelength imaging, many researchers devoted themselves to investigating this methodology. However, due to the free propagating feature of the traditional structured…

Uncovering the heterogeneity of cell populations is a long-standing goal in fields ranging from antimicrobial resistance to cancer research. Emerging technology platforms such as droplet microfluidics hold the promise to decipher cellular…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Vasileios Anagnostidis , Benjamin Sherlock , Jeremy Metz , Philip Mair , Florian Hollfelder , Fabrice Gielen

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

This paper provides a mathematical analysis of ultrafast ultrasound imaging. This newly emerging modality for biomedical imaging uses plane waves instead of focused waves in order to achieve very high frame rates. We derive the point spread…

Numerical Analysis · Mathematics 2017-01-09 Giovanni S. Alberti , Habib Ammari , Francisco Romero , Timothée Wintz

Using the complementary wave- and particle-like natures of photons, it is possible to make ``interaction-free'' measurements where the presence of an object can be determined with no photons being absorbed. We investigated several…

Quantum Physics · Physics 2009-10-31 Andrew G. White , Jay R. Mitchell , Olaf Nairz , Paul G. Kwiat

As the frontline data for cancer diagnosis, microscopic pathology images are fundamental for providing patients with rapid and accurate treatment. However, despite their practical value, the deep learning community has largely overlooked…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Sungrae Hong , Hyeongmin Park , Youngsin Ko , Sol Lee , Bryan Wong , Mun Yong Yi

We introduce a new image cytometer design for detection of very small particulate and demonstrate its capability in water analysis. The device is a compact microscope composed of off the shelf components, such as a light emitting diode…

Optics · Physics 2016-02-17 Juan Miguel Pérez , Marc Jofre , Pedro Martínez , Valerio Pruneri

Recent ultrasound imaging modalities based on ultrasound computed tomography indicate a huge potential to detect pathologies is tissue due to altered biomechanical properties. Especially the imaging of speed-of-sound (SoS) distribution in…

Medical Physics · Physics 2021-07-05 Richard Rau , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

Scanning transmission electron microscopy (STEM) is a powerful tool to reveal the morphologies and structures of materials, thereby attracting intensive interests from the scientific and industrial communities. The outstanding spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Hanlei Zhang , Jincheng Bai , Xiabo Chen , Can Li , Chuanjian Zhong , Jiye Fang , Guangwen Zhou

Polarisation imaging is used to distinguish objects and surface characteristics that are otherwise not visible with black-and-white or colour imaging. Full-Stokes polarisation imaging allows complex image processing like water glint…

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

Phase imaging is widely used in biomedical imaging, sensing, and material characterization, among other fields. However, direct imaging of phase objects with subwavelength resolution remains a challenge. Here, we demonstrate subwavelength…

Optical investigations on the dynamics of dense suspensions are challenging due to reduced optical accessibility. Furthermore, the suspension particle image size can strongly deviate from the optimal particle image size for PIV…

Fluid Dynamics · Physics 2021-09-22 Sebastian Blahout , Simon R. Reinecke , Harald Kruggel-Emden , Jeanette Hussong

Accelerating imaging speed in optical microscopy is often realized at the expense of image contrast, image resolution, and detection sensitivity- a common predicament for advancing high-speed and high-throughput cellular imaging. We here…

Quantitative analysis of the dynamics of tiny cellular and sub-cellular structures, known as particles, in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-07-24 Seyed Hamid Rezatofighi , Stephen Gould , Ba Tuong Vo , Ba-Ngu Vo , Katarina Mele , Richard Hartley

Imaging of surface adsorbed molecules is investigated as a novel detection method for matter wave interferometry with fluorescent particles. Mechanically magnified fluorescence imaging turns out to be an excellent tool for recording quantum…

Quantum Physics · Physics 2009-11-13 Alexander Stibor , Andre Stefanov , Fabienne Goldfarb , Elisabeth Reiger , Markus Arndt

Three-dimensional particle tracking is an essential tool in studying dynamics under the microscope, namely, fluid dynamics in microfluidic devices, bacteria taxis, cellular trafficking. The 3d position can be determined using 2d imaging…

Computer Vision and Pattern Recognition · Computer Science 2015-09-08 Eldad Afik