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Biophysical models of diffusion tailored to quantify gray matter microstructure are gathering increasing interest. The two-compartment Neurite EXchange Imaging ($NEXI$) model has been proposed recently to account for neurites,…

Biophysical models of diffusion in white matter are based on what is now commonly referred to as the "Standard Model" (SM) of non-exchanging anisotropic Gaussian compartments. In this work, we focus on diffusion MRI in gray matter, which…

Biophysical models in diffusion MRI (dMRI) hold promise for characterizing gray matter tissue microstructure. Yet, the reliability of their parameter estimates remains largely under-studied, especially in models that incorporate water…

Exchange between tissue compartments is crucial for interpretation of diffusion MRI measurements in brain gray matter. However, reported values of exchange time are broadly dispersed, about two orders of magnitude. We analyze the…

Biological Physics · Physics 2026-03-24 Valerij G. Kiselev , Jing-Rebecca Li

Diffusion MRI affords valuable insights into white matter microstructures, but suffers from low signal-to-noise ratio (SNR), especially at high diffusion weighting (i.e., b-value). To avoid time-intensive repeated acquisition,…

Medical Physics · Physics 2018-07-26 Geng Chen , Yafeng Wu , Dinggang Shen , Pew-Thian Yap

AI-native architectures are vital for 6G wireless communications. The black-box nature and high complexity of deep learning models employed in critical applications, such as channel estimation, limit their practical deployment. While…

Machine Learning · Computer Science 2026-02-27 Abdul Karim Gizzini , Yahia Medjahdi

Purpose: The clinical feasibility and translation of many advanced quantitative MRI (qMRI) techniques are inhibited by their restriction to 'research mode', due to resource-intensive, offline parameter estimation. This work aimed to achieve…

High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…

Applications · Statistics 2021-11-12 William Consagra , Arun Venkataraman , Zhengwu Zhang

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

Explainable artificial intelligence (XAI) enhances AI system transparency by framing interpretability as an optimization problem. However, this approach often necessitates numerous iterations of computationally intensive operations,…

Artificial Intelligence · Computer Science 2026-01-30 Ayesha Siddique , Khurram Khalil , Khaza Anuarul Hoque

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

Knowledge of the noise distribution in diffusion MRI is the centerpiece to quantify uncertainties arising from the acquisition process. Accurate estimation beyond textbook distributions often requires information about the acquisition…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Samuel St-Jean , Alberto De Luca , Chantal M. W. Tax , Max A. Viergever , Alexander Leemans

Currently, the X-ray detectors are widely used in medical imaging, industrial inspection, aerospace, and other fields, as the market demand for high-efficiency, flexible, and low-power detectors is increased. Although the traditional…

Instrumentation and Detectors · Physics 2025-12-09 Qiao Wang , Pengfei Li , Yushou Song , Jalu Li , Haiying Xiao , Yuqing Wang , Guoliang Ma , Hsu-Sheng Tsai , Ping-An Hu

Explainable AI (XAI) is an active research area to interpret a neural network's decision by ensuring transparency and trust in the task-specified learned models. Recently, perturbation-based model analysis has shown better interpretation,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Mahesh Sudhakar , Sam Sattarzadeh , Konstantinos N. Plataniotis , Jongseong Jang , Yeonjeong Jeong , Hyunwoo Kim

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

This paper presents a Physics-\textit{Explainable AI} (XAI) framework to validate and interpret neural networks for the constitutive modeling of solid materials. The study bridges the gap between data-driven models and continuum mechanics…

Materials Science · Physics 2025-12-03 Chandana Pati , S. M. Mallikarjunaiah

Explainable AI (XAI) methods are frequently applied to obtain qualitative insights about deep models' predictions. However, such insights need to be interpreted by a human observer to be useful. In this paper, we aim to use explanations…

Computer Vision and Pattern Recognition · Computer Science 2022-10-24 Sunsheng Gu , Vahdat Abdelzad , Krzysztof Czarnecki

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi
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