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Objective. Elevated intracranial pressure (ICP) is recognized as a biomarker of secondary brain injury, with a significant linear correlation observed between optic nerve sheath diameter (ONSD) and ICP. Frequent monitoring of ONSD could…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Renxing Li , Weiyi Tang , Peiqi Li , Qiming Huang , Jiayuan She , Shengkai Li , Haoran Xu , Yeyun Wan , Jing Liu , Hailong Fu , Xiang Li , Jiangang Chen

Detecting elevated intracranial pressure (ICP) is crucial in diagnosing and managing various neurological conditions. These fluctuations in pressure are transmitted to the optic nerve sheath (ONS), resulting in changes to its diameter,…

Accurate noninvasive estimation of intracranial pressure (ICP) remains a major challenge in critical care. We developed a bespoke machine learning algorithm that integrates system identification and ranking-constrained optimization to…

Precise management of patients with cerebral diseases often requires intracranial pressure (ICP) monitoring, which is highly invasive and requires a specialized ICU setting. The ability to noninvasively estimate ICP is highly compelling as…

Medical Physics · Physics 2019-08-27 Jian-Xun Wang , Xiao Hu , Shawn C. Shadden

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Accurate and continuous blood pressure (BP) monitoring is essential to the early prevention of cardiovascular diseases. Non-invasive and cuff-less BP estimation algorithm has gained much attention in recent years. Previous studies have…

Machine Learning · Computer Science 2023-11-27 Bufang Yang , Le Liu , Wenxuan Wu , Mengliang Zhou , Hongxing Liu , Xinbao Ning

This paper introduces a learning-based control framework for a soft robotic actuator system designed to modulate intracranial pressure (ICP) waveforms, which is essential for studying cerebrospinal fluid dynamics and pathological processes…

Robust and accurate pose estimation of a robotic platform, so-called sensor-based odometry, is an essential part of many robotic applications. While many sensor odometry systems made progress by adding more complexity to the ego-motion…

Computational fluid dynamics (CFD) studies have been increasingly used for blood flow simulations in intracranial aneurysms (ICAs). However, despite the continuous progress of body-fitted CFD solvers, generating a high quality mesh is still…

Computational Engineering, Finance, and Science · Computer Science 2020-07-28 D. S. Lampropoulos , G. C. Bourantas , B. F. Zwick , G. C. Kagadis , A. Wittek , K. Miller , V. C. Loukopoulos

Purpose: To evaluate a fully-automated deep-learning-based method for assessment of intracranial carotid artery calcification (ICAC). Methods: Two observers manually delineated ICAC in non-contrast CT scans of 2,319 participants (mean age…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Gerda Bortsova , Daniel Bos , Florian Dubost , Meike W. Vernooij , M. Kamran Ikram , Gijs van Tulder , Marleen de Bruijne

Intraoperative pathology is pivotal to precision surgery, yet its clinical impact is constrained by diagnostic complexity and the limited availability of high-quality frozen-section data. While computational pathology has made significant…

Chronic obstructive pulmonary disease (COPD) represents a significant global health burden, where precise severity assessment is particularly critical for effective clinical management in intensive care unit (ICU) settings. This study…

Machine Learning · Computer Science 2025-04-29 Akram Shojaei , Mehdi Delrobaei

The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses, which mainly depends on computational fluid dynamics (CFD). However, current segmentation methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Feiyang Xiao , Yichi Zhang , Xigui Li , Yuanye Zhou , Chen Jiang , Xin Guo , Limei Han , Yuxin Li , Fengping Zhu , Yuan Cheng

We present a novel framework for analyzing intracranial pressure monitoring data by applying interpretability principles. Intracranial pressure monitoring data was collected from 60 patients at Johns Hopkins. The data was segmented into…

Quantitative Methods · Quantitative Biology 2026-01-13 Jonathan D. Socha , Seyed F. Maroufi , Dipankar Biswas , Richard Um , Aruna S. Rao , Mark G. Luciano

Oscillometric monitors are the most common automated blood pressure (BP) measurement devices used in non-specialist settings. However, their accuracy and reliability vary under different settings and for different age groups and health…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Niloufar Delfan , Mohamad Forouzanfar

Coronary microvascular dysfunction (CMD), characterized by impaired regulation of blood flow in the coronary microcirculation, plays a key role in the pathogenesis of ischemic heart disease and is increasingly recognized as a contributor to…

Computational Engineering, Finance, and Science · Computer Science 2025-12-25 Haizhou Yang , Jiyang Zhang , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

This paper presents a visual-inertial odometry-enhanced geometrically stable Iterative Closest Point (ICP) algorithm for accurate mapping using aerial robots. The proposed method employs a visual-inertial odometry framework in order to…

Robotics · Computer Science 2018-01-30 Tung Dang , Shehryar Khattak , Christos Papachristos , Kostas Alexis

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

Imaging the brain vasculature can be critical for cerebral perfusion monitoring in the context of neurocritical care. Although ultrasensitive Doppler (UD) can provide good sensitivity to cerebral blood volume (CBV) in a large field of view,…

Neurons and Cognition · Quantitative Biology 2023-04-12 Anatole Jimenez , Bruno Osmanski , Denis Vivien , Mickael Tanter , Thomas Gaberel , Thomas Deffieux

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

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