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Skin lesion is a severe disease in world-wide extent. Early detection of melanoma in dermoscopy images significantly increases the survival rate. However, the accurate recognition of melanoma is extremely challenging due to the following…

Computer Vision and Pattern Recognition · Computer Science 2017-11-23 Yuexiang Li , Linlin Shen

Due to morphological similarity at the microscopic level, making an accurate and time-sensitive distinction between blood cells affected by Acute Lymphocytic Leukemia (ALL) and their healthy counterparts calls for the usage of machine…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Sai Mattapalli , Rishi Athavale

Monitoring the effects of the chemotherapeutic agent Taxol at the cellular level is critical for both clinical evaluation and biomedical research. However, existing detection methods require specialized equipment, skilled personnel, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sean Fletcher , Gabby Scott , Douglas Currie , Xin Zhang , Yuqi Song , Bruce MacLeod

The evaluation of lymph node metastases plays a crucial role in achieving precise cancer staging, influencing subsequent decisions regarding treatment options. Lymph node detection poses challenges due to the presence of unclear boundaries…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Sofija Engelson , Jan Ehrhardt , Timo Kepp , Joshua Niemeijer , Heinz Handels

The poor contrast and the overlapping of cervical cell cytoplasm are the major issues in the accurate segmentation of cervical cell cytoplasm. This paper presents an automated unsupervised cytoplasm segmentation approach which can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-16 Pranav Kumar , S L Happy , Swarnadip Chatterjee , Debdoot Sheet , Aurobinda Routray

Digitization of histology images and the advent of new computational methods, like deep learning, have helped the automatic grading of colorectal adenocarcinoma cancer (CRA). Present automated CRA grading methods, however, usually use tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Neda Zamanitajeddin , Mostafa Jahanifar , Nasir Rajpoot

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among…

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

Classification of cancer cellularity within tissue samples is currently a manual process performed by pathologists. This process of correctly determining cancer cellularity can be time intensive. Deep Learning (DL) techniques in particular…

Image and Video Processing · Electrical Eng. & Systems 2022-11-10 Jacob D. Beckmann , Kosta Popovic

Comprehensive semantic segmentation on renal pathological images is challenging due to the heterogeneous scales of the objects. For example, on a whole slide image (WSI), the cross-sectional areas of glomeruli can be 64 times larger than…

Image and Video Processing · Electrical Eng. & Systems 2023-01-20 Ruining Deng , Quan Liu , Can Cui , Tianyuan Yao , Jun Long , Zuhayr Asad , R. Michael Womick , Zheyu Zhu , Agnes B. Fogo , Shilin Zhao , Haichun Yang , Yuankai Huo

Understanding a surgical scene is crucial for computer-assisted surgery systems to provide any intelligent assistance functionality. One way of achieving this scene understanding is via scene segmentation, where every pixel of a frame is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Alexander C. Jenke , Sebastian Bodenstedt , Fiona R. Kolbinger , Marius Distler , Jürgen Weitz , Stefanie Speidel

Foundation models are reshaping computational histopathology, yet their value for whole-slide image retrieval relative to strong patch-based and supervised aggregation baselines remains unclear. We benchmarked ten pipelines on 9,387…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tianhao Lei , Parsa Esmaeilkhani , Saghir Alfasly , Wataru Uegami , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Large-scale cell microscopy screens are used in drug discovery and molecular biology research to study the effects of millions of chemical and genetic perturbations on cells. To use these images in downstream analysis, we need models that…

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Data augmentation plays a crucial role in addressing the challenge of limited expert-annotated datasets in deep learning applications for retinal Optical Coherence Tomography (OCT) scans. This work exhaustively investigates the impact of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Markus Unterdechler , Botond Fazekas , Guilherme Aresta , Hrvoje Bogunović

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang