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Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

Enabling Large Language Models (LLMs) to comprehend the 3D physical world remains a significant challenge. Due to the lack of large-scale 3D-text pair datasets, the success of LLMs has yet to be replicated in 3D understanding. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Yuan Tang , Xu Han , Xianzhi Li , Qiao Yu , Jinfeng Xu , Yixue Hao , Long Hu , Min Chen

Training Artificial Intelligence (AI) models on 3D images presents unique challenges compared to the 2D case: Firstly, the demand for computational resources is significantly higher, and secondly, the availability of large datasets for…

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Multi-modal large language models (MLLMs) have rapidly advanced in visual tasks, yet their spatial understanding remains limited to single images, leaving them ill-suited for physical-world applications that require multi-frame reasoning.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Runsen Xu , Weiyao Wang , Hao Tang , Xingyu Chen , Xiaodong Wang , Fu-Jen Chu , Matt Feiszli , Kevin J. Liang

Recent advances in 3D generation have improved the fidelity and geometric details of synthesized 3D assets. However, due to the inherent ambiguity of single-view observations and the lack of robust global structural priors caused by limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wenyue Chen , Wenjue Chen , Peng Li , Qinghe Wang , Xu Jia , Heliang Zheng , Rongfei Jia , Yuan Liu , Ronggang Wang

Recent advancements in multi-modal 3D pre-training methods have shown promising efficacy in learning joint representations of text, images, and point clouds. However, adopting point clouds as 3D representation fails to fully capture the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Haoyuan Li , Yanpeng Zhou , Tao Tang , Jifei Song , Yihan Zeng , Michael Kampffmeyer , Hang Xu , Xiaodan Liang

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

The development of 3D medical vision-language models holds significant potential for disease diagnosis and patient treatment. However, compared to 2D medical images, 3D medical images, such as CT scans, face challenges related to limited…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Haoran Lai , Zihang Jiang , Qingsong Yao , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Wei Wei , Weifu Lv , S. Kevin Zhou

Large Language Models(LLMs) have revolutionized text generation and multimodal perception,but their capabilities in 3D content generation remain underexplored. Existing methods compromise by producing either low-resolution meshes or coarse…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Junming Huang , Chi Wang , Letian Li , Guangkai Xu , Donglin Huang , Hao Chen , Qiang Dai , Weiwei Xu

In this paper, we introduce ILLUME, a unified multimodal large language model (MLLM) that seamlessly integrates multimodal understanding and generation capabilities within a single large language model through a unified next-token…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chunwei Wang , Guansong Lu , Junwei Yang , Runhui Huang , Jianhua Han , Lu Hou , Wei Zhang , Hang Xu

Large vision-language models (VLMs) show strong multimodal understanding but still struggle with 3D spatial reasoning, such as distance estimation, size comparison, and cross-view consistency. Existing 3D-aware methods either depend on…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Ruosen Zhao , Zhikang Zhang , Jialei Xu , Jiahao Chang , Dong Chen , Lingyun Li , Weijian Sun , Zizhuang Wei

Current medical vision-language models (VLMs) process volumetric brain MRI using 2D slice-based approximations, fragmenting the spatial context required for accurate neuroradiological interpretation. We developed \textbf{Brain3D}, a staged…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mariano Barone , Francesco Di Serio , Giuseppe Riccio , Antonio Romano , Marco Postiglione , Antonino Ferraro , Vincenzo Moscato

This paper introduces an innovative approach to Medical Vision-Language Pre-training (Med-VLP) area in the specialized context of radiograph representation learning. While conventional methods frequently merge textual annotations into…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Hanqi Jiang , Xixuan Hao , Yuzhou Huang , Chong Ma , Jiaxun Zhang , Yi Pan , Ruimao Zhang

Large Vision-Language Models (LVLMs) have shown impressive capabilities across a range of tasks that integrate visual and textual understanding, such as image captioning and visual question answering. These models are trained on large-scale…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Xiaomei Zhang , Hanyu Zheng , Xiangyu Zhu , Jinghuan Wei , Junhong Zou , Zhen Lei , Zhaoxiang Zhang

In the real world, a molecule is a 3D geometric structure. Compared to 1D SMILES sequences and 2D molecular graphs, 3D molecules represent the most informative molecular modality. Despite the rapid progress of autoregressive-based language…

Computational Engineering, Finance, and Science · Computer Science 2025-08-15 Lei Jiang , Shuzhou Sun , Biqing Qi , Yuchen Fu , Xiaohua Xu , Yuqiang Li , Dongzhan Zhou , Tianfan Fu

We introduce InternVL3, a significant advancement in the InternVL series featuring a native multimodal pre-training paradigm. Rather than adapting a text-only large language model (LLM) into a multimodal large language model (MLLM) that…

Images in the medical domain are fundamentally different from the general domain images. Consequently, it is infeasible to directly employ general domain Visual Question Answering (VQA) models for the medical domain. Additionally, medical…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Yash Khare , Viraj Bagal , Minesh Mathew , Adithi Devi , U Deva Priyakumar , CV Jawahar

Multimodal large language models (MLLMs) combine visual and textual data for tasks such as image captioning and visual question answering. Proper uncertainty calibration is crucial, yet challenging, for reliable use in areas like healthcare…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Zijun Chen , Wenbo Hu , Guande He , Zhijie Deng , Zheng Zhang , Richang Hong

The recent integration of artificial intelligence into medical imaging has driven remarkable advances in automated organ segmentation. However, most existing 3D segmentation frameworks rely exclusively on visual learning from large…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Hasan Faraz Khan , Noor Fatima , Muzammil Behzad