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Computer-assisted diagnosis (CAD) based on deep learning has become a crucial diagnostic technology in the medical industry, effectively improving diagnosis accuracy. However, the scarcity of brain tumor Magnetic Resonance (MR) image…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Panjian Huang , Xu Liu , Yongzhen Huang

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Score-based diffusion models demonstrate superior performance in generative tasks but encounter fundamental bottlenecks in inverse problems due to the analytical intractability of the time-dependent likelihood score. To bridge this gap, we…

Optimization and Control · Mathematics 2026-05-28 Boyang Zhang , Zhiguo Wang , Ya-Feng Liu

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Mengxiao Geng , Zijie Chen , Ran Hong , Bingxuan Li , Qiegen Liu

Demographic attributes such as age, sex, and race can be predicted from medical images, raising concerns about bias in clinical AI systems. In brain MRI, this signal may arise from anatomical variation, acquisition-dependent contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Mehmet Yigit Avci , Akshit Achara , Andrew King , Jorge Cardoso

Undersampling is a common method in Magnetic Resonance Imaging (MRI) to subsample the number of data points in k-space, reducing acquisition times at the cost of decreased image quality. A popular approach is to employ undersampling…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Tobias Weber , Michael Ingrisch , Bernd Bischl , David Rügamer

Denoising diffusion probabilistic models enable high-fidelity image synthesis and editing. In biomedicine, these models facilitate counterfactual image editing, producing pairs of images where one is edited to simulate hypothetical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Malek Ben Alaya , Daniel M. Lang , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

Artificial intelligence (AI) in healthcare, especially in medical imaging, faces challenges due to data scarcity and privacy concerns. Addressing these, we introduce Med-DDPM, a diffusion model designed for 3D semantic brain MRI synthesis.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-22 Zolnamar Dorjsembe , Hsing-Kuo Pao , Sodtavilan Odonchimed , Furen Xiao

Continuous Conditional Generative Modeling (CCGM) estimates high-dimensional data distributions, such as images, conditioned on scalar continuous variables (aka regression labels). While Continuous Conditional Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Xin Ding , Yongwei Wang , Kao Zhang , Z. Jane Wang

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Ptychography is a well-established coherent diffraction imaging technique that enables non-invasive imaging of samples at a nanometer scale. It has been extensively used in various areas such as the defense industry or materials science.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Semih Barutcu , Doğa Gürsoy , Aggelos K. Katsaggelos

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

Machine Learning · Statistics 2017-10-31 Dustin Tran , David M. Blei

The development of accurate medical image classification models is often constrained by privacy concerns and data scarcity for certain conditions, leading to small and imbalanced datasets. To address these limitations, this study explores…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Iman Khazrak , Shakhnoza Takhirova , Mostafa M. Rezaee , Mehrdad Yadollahi , Robert C. Green , Shuteng Niu

Cardiac Magnetic Resonance (CMR) imaging is a vital non-invasive tool for diagnosing heart diseases and evaluating cardiac health. However, the limited availability of large-scale, high-quality CMR datasets poses a major challenge to the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Ziyu Li , Yujian Hu , Zhengyao Ding , Yiheng Mao , Haitao Li , Fan Yi , Hongkun Zhang , Zhengxing Huang

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan

Corneal diseases are the most common eye disorders. Deep learning techniques are used to per-form automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-30 Samer Kais Jameel , Sezgin Aydin , Nebras H. Ghaeb , Jafar Majidpour , Tarik A. Rashid , Sinan Q. Salih , P. S. JosephNg

Counterfactual medical image generation enables clinicians to explore clinical hypotheses, such as predicting disease progression, facilitating their decision-making. While existing methods can generate visually plausible images from…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Chenglong Ma , Yuanfeng Ji , Jin Ye , Lu Zhang , Ying Chen , Tianbin Li , Mingjie Li , Junjun He , Hongming Shan

Due to the three-dimensional nature of CT- or MR-scans, generative modeling of medical images is a particularly challenging task. Existing approaches mostly apply patch-wise, slice-wise, or cascaded generation techniques to fit the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Paul Friedrich , Julia Wolleb , Florentin Bieder , Alicia Durrer , Philippe C. Cattin