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Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…

Populations and Evolution · Quantitative Biology 2026-01-27 Alex Viguerie , Malú Grave , Alvaro L. G. A. Coutinho , Alessandro Veneziani , Thomas J. R. Hughes

In this work, a hepatitis B virus infection dynamics model is proposed including the spatial dependence of viruses. The existence of traveling waves for the proposed model is established through the application of the celebrated Gersgorin…

Dynamical Systems · Mathematics 2024-02-06 Rupchand Sutradhar , D C Dalal

Understanding interactions between the spread of multiple pathogens during an epidemic is crucial to assessing the severity of infections in human communities. In this paper, we introduce two new Multiplex Bi-Virus Reaction-Diffusion models…

Physics and Society · Physics 2025-08-22 Alyssa Yu , Laura P. Schaposnik

This paper investigates a class of reaction-diffusion population models defined on a bounded domain, characterized by a general time-delayed per capita growth rate and a general advection term. Notably, the growth rate encompasses both…

Dynamical Systems · Mathematics 2025-12-04 Jingxiao Song , Chengwei Ren , Shaofen Zou

Robustness of spatial pattern against perturbations is an indispensable property of developmental processes for organisms, which need to adapt to changing environments. Although specific mechanisms for this robustness have been extensively…

Adaptation and Self-Organizing Systems · Physics 2017-04-05 Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

This paper is concerned with the robustness of the sustained oscillations predicted by an epidemic ODE model defined on contact networks. The model incorporates the spread of awareness among individuals and, moreover, a small inflow of…

Populations and Evolution · Quantitative Biology 2020-11-11 David Juher , David Rojas , Joan Saldaña

In this work we have investigated the evolutionary dynamics of a generalist pathogen, e.g. a virus population, that evolves towards specialisation in an environment with multiple host types. We have particularly explored under which…

Dynamical Systems · Mathematics 2020-06-24 Anel Nurtay , Matthew G. Hennessy , Lluís Alsedà , Santiago F. Elena , Josep Sardanyés

The paper introduces an approach to identify a set of spatially constrained homogeneous areas maximally homogeneous in terms of epidemic trends. The proposed hierarchical algorithm is based on the Dynamic TimeWarping distances between…

Applications · Statistics 2020-06-08 Roberto Benedetti , Federica Piersimoni , Giacomo Pignataro , Francesco Vidoli

Interactions between commuting individuals can lead to large-scale spreading of rumors, ideas, or disease, even though the commuters have no net displacement. The emergent dynamics depend crucially on the commuting distribution of a…

Populations and Evolution · Quantitative Biology 2023-05-30 Aaron Winn , Adam Konkol , Eleni Katifori

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

The COVID-19 outbreak has stimulated the interest in the proposal of novel epidemiological models to predict the course of the epidemic so as to help planning effective control strategies. In particular, in order to properly interpret the…

Machine Learning · Computer Science 2021-01-29 Andrea Zugarini , Enrico Meloni , Alessandro Betti , Andrea Panizza , Marco Corneli , Marco Gori

A ternary reaction-diffusion model for early HIV infection dynamics, incorporating logistic growth of target cells, is introduced. According to in vitro and in vivo studies, random movement of target cells, infected cells, and virions and a…

Populations and Evolution · Quantitative Biology 2024-10-21 Florinda Capone , Roberta De Luca , Vincenzo Luongo

We study the tipping point collective dynamics of an adaptive susceptible-infected-susceptible (SIS) epidemiological network in a data-driven, machine learning-assisted manner. We identify a parameter-dependent effective stochastic…

Machine Learning · Computer Science 2023-11-14 Nikolaos Evangelou , Tianqi Cui , Juan M. Bello-Rivas , Alexei Makeev , Ioannis G. Kevrekidis

We focus on the modeling and simulation of an infectious disease spreading in a medium size population occupying a confined environment, such as an airport terminal, for short periods of time. Because of the size of the crowd and venue, we…

Physics and Society · Physics 2021-07-27 Daewa Kim , Annalisa Quaini

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

We analyze four models of epidemic spreading using a stochastic approach in which the primary stochastic variables are the numbers of individuals in each class. The stochastic approach is described by a master equation and the transition…

Statistical Mechanics · Physics 2020-10-28 Tânia Tomé , Mário J. de Oliveira

The annual occurrence of many infectious diseases remains a constant burden to public health systems. The seasonal patterns in respiratory disease incidence observed in temperate regions have been attributed to the impact of environmental…

Populations and Evolution · Quantitative Biology 2013-11-13 Marguerite Robinson , Yannis Drossinos , Nikolaos I. Stilianakis

The temporal dynamics of social interactions were shown to influence the spread of disease. Here, we model the conditions of progression and competition for several viral strains, exploring various levels of cross-immunity over temporal…

Physics and Society · Physics 2022-06-14 Alex Abbey , Yuval Shahar , Osnat Mokryn

We study a PDE model for dynamics of susceptible-infected interactions. The dispersal of susceptibles is via diffusion and repellent taxis as they move away from the increasing density of infected. The diffusion of infected is a nonlinear,…

Analysis of PDEs · Mathematics 2019-02-07 Chiganga Samson Ruoja , Christina Surulescu , Anna Zhigun

Statistical models used to estimate the spatio-temporal pattern in disease risk from areal unit data represent the risk surface for each time period with known covariates and a set of spatially smooth random effects. The latter act as a…

Applications · Statistics 2016-04-19 Alastair Rushworth , Duncan Lee , Christophe Sarran