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Health data is a sensitive category of personal data. It might result in a high risk to individual and health information handling rights and opportunities unless there is a palatable defense. Reasonable security standards are needed to…

Cryptography and Security · Computer Science 2020-10-21 Ayan Chatterjee , Ali Shahaab , Martin W. Gerdes , Santiago Martinez , Pankaj Khatiwada

Electronic Health Records (EHRs) provide high-dimensional temporal data essential for patient modeling; however, conventional algorithmic approaches often rely on data aggregation or imputation, which distorts temporal disease trajectories.…

Machine Learning · Computer Science 2026-04-21 Pi-Ju Tsai , Charkkri Limbud , Kuan-Fu Chen , Yi-Ju Tseng

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

Legacy Electronic Health Records (EHRs) systems were not developed with the level of connectivity expected from them nowadays. Therefore, interoperability weakness inherent in the legacy systems can result in poor patient care and waste of…

Software Engineering · Computer Science 2018-08-24 Yilong Yang , Xiaoshan Li , Nafees Qamar , Wei Ke , Zhiming Liu

Electronic Health Records (EHRs) have been increasingly used as real-world evidence (RWE) to support the discovery and validation of new drug indications. This paper surveys current approaches to EHR-based drug repurposing, covering data…

Applications · Statistics 2025-11-21 Nabasmita Talukdar , Xiaodan Zhang , Shreya Paithankar , Hui Wang , Bin Chen

The same real-world entity (e.g., a movie, a restaurant, a person) may be described in various ways on different datasets. Entity Resolution (ER) aims to find such different descriptions of the same entity, this way improving data quality…

Databases · Computer Science 2025-03-18 Konstantinos Nikoletos , Vasilis Efthymiou , George Papadakis , Kostas Stefanidis

Patient datasets contain confidential information which is protected by laws and regulations such as HIPAA and GDPR. Ensuring comprehensive patient information necessitates privacy-preserving entity resolution (PPER), which identifies…

Computational Engineering, Finance, and Science · Computer Science 2024-05-29 Yixiang Yao , Joseph Cecil , Praveen Angyan , Neil Bahroos , Srivatsan Ravi

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Estimation of heterogeneous treatment effects is an essential component of precision medicine. Model and algorithm-based methods have been developed within the causal inference framework to achieve valid estimation and inference. Existing…

Methodology · Statistics 2021-05-10 Ruohong Li , Honglang Wang , Wanzhu Tu

Transformer-based models have improved predictive modeling on longitudinal electronic health records through large-scale self-supervised pretraining. However, most EHR transformer architectures treat each clinical encounter as an unordered…

Machine Learning · Computer Science 2026-03-17 Krish Tadigotla

Clinical Reasoning on Electronic Health Records (EHRs) is a fundamental yet challenging task in modern healthcare. While in-context learning (ICL) offers a promising inference-time adaptation paradigm for large language models (LLMs) in EHR…

Machine Learning · Computer Science 2026-04-09 Yue Fang , Weibin Liao , Yuxin Guo , Jiaran Gao , Hongxin Ding , Jinyang Zhang , Xinke Jiang , Zhibang Yang , Junfeng Zhao , Yasha Wang , Liantao Ma

Motivation: Electronic health record (EHR) data provides a new venue to elucidate disease comorbidities and latent phenotypes for precision medicine. To fully exploit its potential, a realistic data generative process of the EHR data needs…

Machine Learning · Computer Science 2021-05-05 Ziyang Song , Xavier Sumba Toral , Yixin Xu , Aihua Liu , Liming Guo , Guido Powell , Aman Verma , David Buckeridge , Ariane Marelli , Yue Li

Text classification tasks which aim at harvesting and/or organizing information from electronic health records are pivotal to support clinical and translational research. However these present specific challenges compared to other…

Computation and Language · Computer Science 2020-05-15 Aurelie Mascio , Zeljko Kraljevic , Daniel Bean , Richard Dobson , Robert Stewart , Rebecca Bendayan , Angus Roberts

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

Multi-institutional electronic health record (Multi-EHR) data have emerged as a powerful resource for developing predictive models to support clinical decisions and for generating reliable real-world evidence. By aggregating information…

Methodology · Statistics 2026-05-12 Yuming Zhang , Congyuan Duan , Dong Xia , Doudou Zhou , Tianxi Cai

Widespread adoption of electronic health records (EHRs) has fueled the development of using machine learning to build prediction models for various clinical outcomes. This process is often constrained by having a relatively small number of…

Computation and Language · Computer Science 2020-05-14 Ethan Steinberg , Ken Jung , Jason A. Fries , Conor K. Corbin , Stephen R. Pfohl , Nigam H. Shah

Electronic health records (EHRs) recorded in hospital settings typically contain a wide range of numeric time series data that is characterized by high sparsity and irregular observations. Effective modelling for such data must exploit its…

Clinical trials are a critical component of evaluating the effectiveness of new medical interventions and driving advancements in medical research. Therefore, timely enrollment of patients is crucial to prevent delays or premature…

Information Retrieval · Computer Science 2023-06-12 Georgios Peikos , Symeon Symeonidis , Pranav Kasela , Gabriella Pasi

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

Information Retrieval · Computer Science 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao
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