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Medical image representations can be learned through medical vision-language contrastive learning (mVLCL) where medical imaging reports are used as weak supervision through image-text alignment. These learned image representations can be…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Mingjian Li , Mingyuan Meng , Michael Fulham , David Dagan Feng , Lei Bi , Jinman Kim

Accurate prognostication and risk estimation are essential for guiding clinical decision-making and optimizing patient management. While radiologist-assessed features from CT scans provide valuable indicators of disease severity and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Xixi Liu , Jorge Lazo , Andreas Hallqvist , Mikael Johansson , Åse Johnsson , Jonas S Andersson , Ella Äng Eklund , Patrik Sund , Nasser Hosseini , Jennifer Alvén , Ida Häggström

Contrastive Language-Image Pre-training (CLIP)~\citep{radford2021learning} has emerged as a pivotal model in computer vision and multimodal learning, achieving state-of-the-art performance at aligning visual and textual representations…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Shaoan Xie , Lingjing Kong , Yujia Zheng , Yu Yao , Zeyu Tang , Eric P. Xing , Guangyi Chen , Kun Zhang

Lung nodule malignancy prediction has been enhanced by advanced deep-learning techniques and effective tricks. Nevertheless, current methods are mainly trained with cross-entropy loss using one-hot categorical labels, which results in…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Yiming Lei , Zilong Li , Yan Shen , Junping Zhang , Hongming Shan

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

Recently, learning open-vocabulary semantic segmentation from text supervision has achieved promising downstream performance. Nevertheless, current approaches encounter an alignment granularity gap owing to the absence of dense annotations,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Yajie Liu , Pu Ge , Qingjie Liu , Di Huang

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Vision-language models (VLMs) show strong potential for complex diagnostic tasks in medical imaging. However, applying VLMs to multi-organ medical imaging introduces two principal challenges: (1) modality-specific vision-language alignment…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Haowen Zhu , Ning Yin , Xiaogen Zhou

Medical foundation models have the potential to revolutionize healthcare by providing robust and generalized representations of medical data. Medical vision-language pre-training has emerged as a promising approach for learning…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Qiao Deng , Zhongzhen Huang , Yunqi Wang , Zhichuan Wang , Zhao Wang , Xiaofan Zhang , Qi Dou , Yeung Yu Hui , Edward S. Hui

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

In recent years, Multimodal Large Language Models (MLLMs) have made significant progress in visual question answering tasks. However, directly applying existing fine-tuning methods to remote sensing (RS) images often leads to issues such as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Qigan Sun , Chaoning Zhang , Jianwei Zhang , Xudong Wang , Jiehui Xie , Pengcheng Zheng , Haoyu Wang , Sungyoung Lee , Chi-lok Andy Tai , Yang Yang , Heng Tao Shen

Self-supervised learning in vision-language processing exploits semantic alignment between imaging and text modalities. Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical…

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein functions. Recent sequence representation learning methods based on Protein Language Models (PLMs) excel in sequence-based…

Quantitative Methods · Quantitative Biology 2023-10-19 Zuobai Zhang , Chuanrui Wang , Minghao Xu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Cross-modal alignment is essential for vision-language pre-training (VLP) models to learn the correct corresponding information across different modalities. For this purpose, inspired by the success of masked language modeling (MLM) tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Yatai Ji , Rongcheng Tu , Jie Jiang , Weijie Kong , Chengfei Cai , Wenzhe Zhao , Hongfa Wang , Yujiu Yang , Wei Liu

Unsupervised 3D representation learning reduces the burden of labeling multimodal 3D data for fusion perception tasks. Among different pre-training paradigms, differentiable-rendering-based methods have shown most promise. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Runjian Chen , Hang Zhang , Avinash Ravichandran , Hyoungseob Park , Wenqi Shao , Alex Wong , Ping Luo

Contrastive Language-Image Pre-training (CLIP) demonstrates strong potential in medical image analysis but requires substantial data and computational resources. Due to these restrictions, existing CLIP applications in medical imaging focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Yuexi Du , John Onofrey , Nicha C. Dvornek

Machine learning methods have recently achieved high-performance in biomedical text analysis. However, a major bottleneck in the widespread application of these methods is obtaining the required large amounts of annotated training data,…

Machine Learning · Computer Science 2019-12-06 Xing Meng , Craig H. Ganoe , Ryan T. Sieberg , Yvonne Y. Cheung , Saeed Hassanpour

Pretraining molecular representations is crucial for drug and material discovery. Recent methods focus on learning representations from geometric structures, effectively capturing 3D position information. Yet, they overlook the rich…

Machine Learning · Computer Science 2024-11-19 Teng Xiao , Chao Cui , Huaisheng Zhu , Vasant G. Honavar

Automated radiology report generation has the potential to improve radiology reporting and alleviate the workload of radiologists. However, the medical report generation task poses unique challenges due to the limited availability of…

Computation and Language · Computer Science 2023-12-27 Ruoqing Zhao , Xi Wang , Hongliang Dai , Pan Gao , Piji Li

Vision-and-Language (V+L) pre-training models have achieved tremendous success in recent years on various multi-modal benchmarks. However, the majority of existing models require pre-training on a large set of parallel image-text data,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Mingyang Zhou , Licheng Yu , Amanpreet Singh , Mengjiao Wang , Zhou Yu , Ning Zhang