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Related papers: Steering Protein Language Models

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With the rapid evolution of global autonomous driving technology, the demand for its core sensing hardware, Light Detection and Ranging (LiDAR), is escalating. As the light source part of the LiDAR system, lasers, particularly the…

Large Language Models (LLMs) and pre-trained Language Models (LMs) have achieved impressive success on many software engineering tasks (e.g., code completion and code generation). By leveraging huge existing code corpora (e.g., GitHub),…

Software Engineering · Computer Science 2025-01-16 Xin Yin , Chao Ni , Xiaodan Xu , Xinrui Li , Xiaohu Yang

Understanding protein sequences is vital and urgent for biology, healthcare, and medicine. Labeling approaches are expensive yet time-consuming, while the amount of unlabeled data is increasing quite faster than that of the labeled data due…

Computation and Language · Computer Science 2021-11-01 Liang He , Shizhuo Zhang , Lijun Wu , Huanhuan Xia , Fusong Ju , He Zhang , Siyuan Liu , Yingce Xia , Jianwei Zhu , Pan Deng , Bin Shao , Tao Qin , Tie-Yan Liu

Prompt engineering has proven to be a crucial step in leveraging pretrained large language models (LLMs) in solving various real-world tasks. Numerous solutions have been proposed that seek to automate prompt engineering by using the model…

Large Language Models (LLMs) have demonstrated great promise in generating code, especially when used inside an evolutionary computation framework to iteratively optimize the generated algorithms. However, in some cases they fail to…

Neural and Evolutionary Computing · Computer Science 2025-03-24 Niki van Stein , Anna V. Kononova , Lars Kotthoff , Thomas Bäck

Designing proteins with desired functions or properties represents a core goal in synthetic biology and drug discovery. Recent advances in protein language models (PLMs) have enabled the generation of highly designable protein sequences,…

Machine Learning · Computer Science 2026-05-12 Yulin Zhang , He Cao , Zihao Jiang , Chenyi Zi , Zhipeng Zhou , Zijing Liu , Yu Li , Jia Li , Ziqi Gao

Recent advancements in language models (LMs) have marked a shift toward the growing importance of post-training. Yet, post-training approaches such as supervised fine-tuning (SFT) do not guarantee the effective use of knowledge acquired…

Computation and Language · Computer Science 2025-10-30 Chunyuan Deng , Ruidi Chang , Hanjie Chen

This paper investigates the capabilities of large language models (LLMs) in formulating and solving decision-making problems using mathematical programming. We first conduct a systematic review and meta-analysis of recent literature to…

Artificial Intelligence · Computer Science 2025-08-26 Mohammad J. Abdel-Rahman , Yasmeen Alslman , Dania Refai , Amro Saleh , Malik A. Abu Loha , Mohammad Yahya Hamed

A Large Language Model (LLM) represents a cutting-edge artificial intelligence model that generates coherent content, including grammatically precise sentences, human-like paragraphs, and syntactically accurate code snippets. LLMs can play…

Software Engineering · Computer Science 2023-12-11 Robson Santos , Italo Santos , Cleyton Magalhaes , Ronnie de Souza Santos

Large-scale Protein Language Models (PLMs) have improved performance in protein prediction tasks, ranging from 3D structure prediction to various function predictions. In particular, AlphaFold, a ground-breaking AI system, could potentially…

Quantitative Methods · Quantitative Biology 2022-10-18 Mingyang Hu , Fajie Yuan , Kevin K. Yang , Fusong Ju , Jin Su , Hui Wang , Fei Yang , Qiuyang Ding

Methods for controlling large language models (LLMs), including local weight fine-tuning, LoRA-based adaptation, and activation-based interventions, are often studied in isolation, obscuring their connections and making comparison…

Computation and Language · Computer Science 2026-04-14 Ziwen Xu , Chenyan Wu , Hengyu Sun , Haiwen Hong , Mengru Wang , Yunzhi Yao , Longtao Huang , Hui Xue , Shumin Deng , Zhixuan Chu , Huajun Chen , Ningyu Zhang

Steering methods for language models (LMs) seek to provide fine-grained and interpretable control over model generations by variously changing model inputs, weights, or representations to adjust behavior. Recent work has shown that…

Computation and Language · Computer Science 2025-05-28 Zhengxuan Wu , Qinan Yu , Aryaman Arora , Christopher D. Manning , Christopher Potts

Steering language model generation toward desired textual properties is essential for practical deployment, and inference-time methods are particularly appealing because they enable controllable generation without retraining. Recent work…

Computation and Language · Computer Science 2026-05-29 Hyeseon An , Yo-Sub Han

Activation steering methods control large language model (LLM) behavior by modifying internal activations at inference time. However, most existing activation steering methods rely on a fixed steering strength, leading to either…

Computation and Language · Computer Science 2025-10-16 Arthur Vogels , Benjamin Wong , Yann Choho , Annabelle Blangero , Milan Bhan

Large Language Models (LLMs) have become extremely potent instruments with exceptional capacities for comprehending and producing human-like text in a wide range of applications. However, the increasing size and complexity of LLMs present…

Machine Learning · Computer Science 2024-06-18 Yingbing Huang , Lily Jiaxin Wan , Hanchen Ye , Manvi Jha , Jinghua Wang , Yuhong Li , Xiaofan Zhang , Deming Chen

Inspired by the exceptional general intelligence of Large Language Models (LLMs), researchers have begun to explore their application in pioneering the next generation of recommender systems - systems that are conversational, explainable,…

Information Retrieval · Computer Science 2024-08-06 Wensheng Lu , Jianxun Lian , Wei Zhang , Guanghua Li , Mingyang Zhou , Hao Liao , Xing Xie

Latent space steering methods provide a practical approach to controlling large language models by applying steering vectors to intermediate activations, guiding outputs toward desired behaviors while avoiding retraining. Despite their…

Machine Learning · Computer Science 2026-01-13 Shawn Im , Sharon Li

Vision Language Models (VLMs) have demonstrated impressive capabilities in integrating visual and textual information for understanding and reasoning, but remain highly vulnerable to adversarial attacks. While activation steering has…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Sihao Wu , Gaojie Jin , Wei Huang , Jianhong Wang , Xiaowei Huang

Controlling multiple behavioral attributes in large language models (LLMs) at inference time is a challenging problem due to interference between attributes and the limitations of linear steering methods, which assume additive behavior in…

Machine Learning · Computer Science 2026-04-07 Narmeen Oozeer , Luke Marks , Shreyans Jain , Fazl Barez , Amirali Abdullah

Adapting models to a language that was only partially present in the pre-training data requires fine-tuning, which is expensive in terms of both data and computational resources. As an alternative to fine-tuning, we explore the potential of…

Computation and Language · Computer Science 2024-11-28 Daniel Scalena , Elisabetta Fersini , Malvina Nissim