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We present the design and \textit{in-silico} evaluation of a closed-loop insulin delivery algorithm to treat type 1 diabetes (T1D) consisting in a data-driven multi-step-ahead blood glucose (BG) predictor integrated into a Linear…

Systems and Control · Electrical Eng. & Systems 2023-07-25 Eleonora Maria Aiello , Mehrad Jaloli , Marzia Cescon

Molecular communication (MC) enables information exchange at the nano- and microscale, with applications in areas like drug delivery and health monitoring. These event-driven scenarios often require alternatives to traditional transmission.…

Information Theory · Computer Science 2025-06-18 Yaning Zhao , Luca Miszewski , Christian Deppe , Massimiliano Pierobon

Driving fatigue is a major contributor to traffic accidents and poses a serious threat to road safety. Electroencephalography (EEG) provides a direct measurement of neural activity, yet EEG-based fatigue recognition is hindered by strong…

Other Computer Science · Computer Science 2026-03-06 Yip Tin Po , Jianming Wang , Yutao Miao , Jiayan Zhang , Yunxu Zhao , Xiaomin Ouyang , Zhihong Li , Nevin L. Zhang

One of the goals of neuroscience is to study interactions between different brain regions during rest and while performing specific cognitive tasks. The Multivariate Bayesian Autoregressive Decomposition (MBMARD) is proposed as an intuitive…

Methodology · Statistics 2023-05-16 Guillermo Granados-Garcia , Raquel Prado , Hernando Ombao

Wireless communication using electro-magnetic (EM) fields acts as the backbone for information exchange among wearable devices around the human body. However, for Implanted devices, EM fields incur high amount of absorption in the tissue,…

Neurons and Cognition · Quantitative Biology 2023-07-06 Baibhab Chatterjee , Mayukh Nath , Gaurav Kumar K , Shulan Xiao , Krishna Jayant , Shreyas Sen

Feedback optimization enables autonomous optimality seeking of a dynamical system through its closed-loop interconnection with iterative optimization algorithms. Among various iteration structures, model-based approaches require the…

Optimization and Control · Mathematics 2026-05-26 Zhiyu He , Saverio Bolognani , Michael Muehlebach , Florian Dörfler

Molecular communication (MC), one of the emerging techniques in the field of communication, is entering a new phase following several decades of foundational research. Recently, attention has shifted toward MC in liquid media, particularly…

Information Theory · Computer Science 2025-06-03 Yun-Feng Lo , Changmin Lee , Chan-Byoung Chae

Motor imagery (MI) based brain-computer interfaces (BCIs) hold significant potential for assistive technologies and neurorehabilitation. However, the precise and efficient decoding of MI remains challenging due to their non-stationary…

Human-Computer Interaction · Computer Science 2025-09-09 Yi Wang , Haodong Zhang , Hongqi Li

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

This paper analyzes a four-dimensional model of the hypothalamic-pituitary-adrenal (HPA) axis that includes the influence of the glucocorticoid receptor in the pituitary. Due to the spatial separation between the hypothalamus, pituitary and…

Optimization and Control · Mathematics 2017-01-31 Eva Kaslik , Dan Bogdan Navolan , Mihaela Neamtu

This paper contributes to the human-machine interface community in two ways: as a critique of the closed-loop AC (augmented cognition) approach, and as a way to introduce concepts from complex systems and systems physiology into the field.…

Human-Computer Interaction · Computer Science 2008-11-11 Bradly Alicea

This paper investigates the secrecy capacity of the binary beampointing (BBP) channel with block memory and feedback, a simplified yet insightful model for millimeter-wave (mmWave) systems with beamformed transmissions and backscatter…

Information Theory · Computer Science 2025-08-29 Siyao Li , Mingzhe Chen , Shuangyang Li , Giuseppe Caire

Presented with sensory challenges, living cells employ extensive noisy, fluctuating signalling and communication among themselves to compute a physiologically proper response which often results in symmetry breaking. We propose, based on…

Biological Physics · Physics 2022-06-17 Dean Korošak , Andraž Stožer , Marjan Slak Rupnik

Brain-Machine Interfacing (BMI) has greatly benefited from adopting machine learning methods for feature learning that require extensive data for training, which are often unavailable from a single dataset. Yet, it is difficult to combine…

Signal Processing · Electrical Eng. & Systems 2024-05-27 Jinpei Han , Xiaoxi Wei , A. Aldo Faisal

In this paper we consider the influence of intercellular communication on the development and progression of Glioblastoma Multiforme (GBM), a grade IV malignant glioma which is defined by an interplay Grow i.e. self renewal and Go i.e.…

Neurons and Cognition · Quantitative Biology 2021-05-03 Hamdan Awan , Andreani Odysseos , Niovi Nicolaou , Sasitharan Balasubramaniam

Animals move smoothly and reliably in unpredictable environments. Models of sensorimotor control have assumed that sensory information from the environment leads to actions, which then act back on the environment, creating a single,…

Neurons and Cognition · Quantitative Biology 2023-01-11 Jing Shuang Li , Anish A. Sarma , Terrence J. Sejnowski , John C. Doyle

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford

There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiome-gut-brain axis.…

Genomics · Quantitative Biology 2023-12-11 Thomaz F. S. Bastiaanssen , Thomas P. Quinn , Amy Loughman

Brain Computer Interface technologies are popular methods of communication between the human brain and external devices. One of the most popular approaches to BCI is Motor Imagery. In BCI applications, the ElectroEncephaloGraphy is a very…

Human-Computer Interaction · Computer Science 2021-06-03 Javier Fumanal-Idocin , Yu-Kai Wang , Chin-Teng Lin , Javier Fernández , Jose Antonio Sanz , Humberto Bustince